Hacettepe University Institutional Repository
Hacettepe University Institutional Repository is a growing collection of Hacettepe University’s research that includes peer-reviewed articles, technical reports, working papers, theses and more.
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Yoğun Bakım Hemşirelerinin Sepsis Belirti Bulguları ile Yönetimine İlişkin Bilgi Düzeylerinin İncelenmesi (Sağlık Bilimleri Enstitüsü, 2020-02-25)Research was conducted as a descriptive study to determine the knowledge level and management interventions of intensive care nurses about the symptoms and signs of sepsis management. The sample of the study consists of ...
The Association of Various Social Capital Indicators and Physical Activity Participation Among Turkish Adolescents (Elsevier, 2018)Background Physical activity participation (PAP) has been proven to improve health and promote optimal growth among adolescents. However, most adolescents do not meet the current physical activity (PA) recommendations in ...
(Elsevier, 2017)Background:Body mass index (BMI) is defined as a poor prognostic factor in patients with breast cancer(BC). However, there are controversial results regarding the various effects of BMI on BC, hence the exactpathophysiology ...
Targeting Plk1 Overcomes T-Dm1 Resistance Via Cdk1-Dependent Phosphorylation and Inactivation Of Bcl-2/Xl In Her2-Positive Breast Cancer (Nature Publishing Group, 2018)Trastuzumab-refractory, HER2 (human epidermal growth factor receptor 2)-positive breast cancer is commonly treated with trastuzumab emtansine (T-DM1), an antibody-drug conjugate of trastuzumab and the microtubule-targeting ...
(Baishideng Publishing Group Inc, 2016)Advanced gastric cancer (AGC) is associated with a high mortality rate and, despite multiple new chemotherapy options, the survival rates of patients with AGC remains poor. After the discovery of targeted therapies, research ...
Tamoxifen-Induced Tissue Factor Pathway Inhibitor Reduction: A Clue For An Acquired Thrombophilic State? (Oxford Univ Press, 2004)Background: Current understanding of hemostatic systems enables us to better explore the enigmatic pathobiology of tamoxifen (TAM)-induced thrombotic diathesis. We have therefore aimed to assess the hemostatic changes in ...
Synthesis, Characterization And Optical Limiting Properties Of Novel Ball-Type Four Tert-ButylcalixArene Bridged Double-Decker Lutetium(Iii) And Indium(Iii) Phthalocyanines (Scimago, 2008)Novel ball type four tert-butylcalixarene bridged double-decker lutetium(III) phthalocyanine [LuPc2(tbca)4] 2 which exhibit nonlinear optical limiting behaviour and indium(III) phthalocyanine [InPc2(tbca)4] 3 were ...
(Amer Assoc Cancer Research, 2018)Mounting clinical and preclinical evidence supports a key role for sustained adrenergic signaling in the tumor microenvironment as a driver of tumor growth and progression. However, the mechanisms by which adrenergic ...