Browsing by Department "Nöroloji"
Now showing items 1-20 of 152
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A Nanomedicine Transports A Peptide Caspase-3 Inhibitor Across The Blood-Brain Barrier And Provides Neuroprotection
(Soc Neuroscience, 2009)Caspases play an important role as mediators of cell death in acute and chronic neurological disorders. Although peptide inhibitors of caspases provide neuroprotection, they have to be administered intracerebroventricularly ... -
A Novel De Novo Mutation Involving the Mll2 Gene in a Kabuki Syndrome Patient Presenting with Seizures
(Turkish J Pediatrics, 2016)Kabuki syndrome is a rare multiple congenital anomaly disorder. Although mental retardation is one of the main features, various neurological symptoms such as hypotonia and seizures can occur. Here we report on a 18-year-old ... -
A Rare Cause of Carpal Tunnel Syndrome in Childhood: Benign Recurrent Intrahepatic Cholestasis
(De Gruyter Poland Sp Zoo, 2010)Carpal tunnel syndrome and benign recurrent intrahepatic cholestasis are rare conditions in childhood. Benign intrahepatic cholestasis is characterized by repeated self-limited attacks of cholestasis that can start at any ... -
Acute Disseminated Encephalomyelitis After Oral Therapy With Herbal Extracts: A Case Report
(Aves, 2016)Background: Acute disseminated encephalomyelitis (ADEM) is a rare demyelinating disease of the central nervous system, commonly attributed to infections or vaccinations. Toxic or allergenic compounds can also trigger a ... -
Alpha-Synuclein Aggregation Induced By Brief Ischemia Negatively Impacts Neuronal Survival in Vivo: A Study in [A30P] Alpha-Synuclein Transgenic Mouse
(Sage Publications Inc, 2011)Alpha-synuclein oligomerization and aggregation are considered to have a role in the pathogenesis of neurodegenerative diseases. However, despite numerous in vitro studies, the impact of aggregates in the intact brain is ... -
Amiyotrofik Lateral Skleroz Hastalarının Deri Biyopsilerinde Epidermal Büyüme Faktörü (Egf) ve Keratinosit Büyüme Faktörünün (Kgf) Ekspresyonunun Değerlendirilmesi
(Tıp Fakültesi, 2017-09-13)Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that causes immobility. Bed sores are an important problem in immobile patients. However, in ALS, it is known that bed sores are less common ... -
Antibiotherapy with and without Bone Debridement in Diabetic Foot Osteomyelitis: A Retrospective Cohort Study
(Professional Medical Publications, 2014)Background and Objective: The treatment of diabetic foot osteomyelitis (DFO) is a controversial issue, with disagreement regarding whether the best treatment is surgical or conservative. The purpose of this study was to ... -
Antiplatelet Resistance in Stroke
(Expert Reviews, 2011)Although the exact prevalence of antiplatelet resistance in ischemic stroke is not known, estimates about the two most widely used antiplatelet agents aspirin and clopidogrel suggest that the resistance rate is high, ... -
Assessment of Citrullinated Myelin By H-1-Mr Spectroscopy in Early-Onset Multiple Sclerosis
(Amer Soc Neuroradiology, 2009)BACKGROUND AND PURPOSE: Myelin instability and citrullinated myelin basic protein have been demonstrated in the brains of patients with chronic and fulminating forms of multiple sclerosis (MS). Our aim was to trace citrulline ... -
Assessment of the Predictive Validity of Etiologic Stroke Classification
(Amer Medical Assoc, 2017)IMPORTANCE The ability of present-day etiologic stroke classification systems to generate subtypes with discrete stroke characteristics is not known. OBJECTIVE To test the hypothesis that etiologic stroke subtyping identifies ... -
Atypical Aicardi-Goutieres Syndrome: Is the Wrn Locus a Modifier?
(Wiley-Blackwell, 2014)We describe a 28-year-old Turkish man with consanguineous parents who presented with an aged appearance with prematurely gray hair and scleroderma-like skin, spastic paraplegia, and apparent disability. The proband and ... -
Benefit Of High-Dose Methylprednisolone In Comparison With Conventional-Dose Prednisolone During Remission Induction Therapy In Childhood Acute Lymphoblastic Leukemia For Long-Term Follow-Up
(Nature Publishing Group, 2003)Eight-year event-free survival (EFS) was evaluated in 205 patients with acute lymphoblastic leukemia (ALL), to consider the efficacy of high-dose methylprednisolone (HDMP) given during remission induction chemotherapy ... -
Blockade of Gaba Synthesis Only Affects Neural Excitability Under Activated Conditions in Rat Hippocampal Slices
(Pergamon-Elsevier Science Ltd, 2008)The primary goal of this study was to establish whether inhibition of GABA synthesis was sufficient to induce network hyperexcitability in a rat hippocampal slice model comparable to that seen with GABA receptor blockade. ... -
Bright and Dark Vessels on Stroke Imaging: Different Sides of The Same Coin?
(Aves, 2016)PURPOSE Prominent hypointense cerebral vessels on susceptibility-weighted imaging (SWI) and the hyperintense vessel sign (HVS) on fluid-attenuated inversion recovery (FLAIR) imaging are considered as markers of compromised ...
