Enstitüler
Recent Submissions
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Smooth Muscle Cells Isolated from Thoracic Aortic Aneurysms Exhibit Increased Genomic Damage, but Similar Tendency for Apoptosis
(Mary Ann Liebert Inc, 2012)Aortic aneurysms (AA) are characterized by structural deterioration leading to progressive dilation. During the development of AA, two key structural changes are pronounced, one being degradation of extracellular matrix ... -
Smoking Induces Coordinated Dna Methylation and Gene Expression Changes in Adipose Tissue with Consequences for Metabolic Health
(Springer Nature, 2018)Background: Tobacco smoking is a risk factor for multiple diseases, including cardiovascular disease and diabetes. Many smoking-associated signals have been detected in the blood methylome, but the extent to which ... -
Smoking Habits of Relatives of Patients with Cancer: Cancer Diagnosis in the Family is an Important Teachable Moment for Smoking Cessation
(Asian Pacific Organization Cancer Prevention, 2013)Background: In this study we aimed to determine the rate and habitual patterns of smoking, intentions of cessation, dependence levels and sociodemographic characteristics of relatives of patients with a diagnosis of cancer. ... -
Single Institution Experience on Cancer Among Adolescents 15-19 Years of Age
(Turkish J Pediatrics, 2017)Adolescent cancers differ from other age groups in terms of cancer types, treatment and outcome. We aimed to present our institutional data on survival of certain types of cancer in adolescents. Hospital files were ... -
Short-Hairpin Rna Silencing Of Endogenous Fibroblast Growth Factor 2 In Rat Hippocampus Increases Anxiety Behavior
(Elsevier Science Inc, 2011)Background: The fibroblast growth factor system has been implicated in the pathophysiology of mood disorders in humans and in affective behavior in animal models. However, the studies have been either correlative or involved ... -
The Neurophysiologic Frequency Of Hereditary Neuropathy With Liability To Pressure Palsy In Entrapment Neuropathies
(Türk Nöroloji Derneği, 2016)"Objective: Hereditary neuropathy with liability to pressure palsy (HNPP) needs to be differentiated from entrapment neuropathies due to differences in the treatment management. Materials and Methods: Among 5075 patients ... -
Serum 25-Hydroxy Vitamin D Status Is Not Related To Osteopenia/Osteoporosis Risk In Colorectal Cancer Survivors
(Asian Pacific Organization Cancer Prevention, 2014)Background: The incidence of colorectal cancer increases with vitamin D deficiency as shown in recently published studies. In addition, prospective investigations have indicated that low vitamin D levels may be associated ... -
The Relationship of Agmatine Deficiency with the Lung Cancer
(Akad Doktorlar Yayınevi, 2016)The polyamines are essential for rapidly growing cells. Polyamines is synthesized by two reactions which begin from arginine. The aim of this study is to examine the serum levels of the enzymes located in the putrescine ... -
MEZENKİMAL KÖK HÜCRE ÜRETİMİNDE İN VİTRO TEMELLİ METABOLOMİK VE ANALİZLER
(Sağlık Bilimleri Enstitüsü, 2020-02-12)Karaağaç Akyol, T. Metabolomic And Analyzes In In-Vitro Based On The Production Of Mesenchimal Stem Cells, Hacettepe University Graduate School of Health Sciences Stem Cells Program Doctor of Philosophy Thesis, Ankara, ... -
Thrombotic Distal Middle Cerebral Artery Occlusion Produced By Topical Fecl3 Application: A Novel Model Suitable For Intravital Microscopy And Thrombolysis Studies
(Nature Publishing Group, 2011)Intravital or multiphoton microscopy and laser-speckle imaging have become popular because they allow live monitoring of several processes during cerebral ischemia. Available rodent models have limitations for these ... -
Transfection Of Myeloid Leukaemia Cell Lines Is Distinctively Regulated By Fibronectin Substratum
(Springer, 2009)Gene transfer into haematopoietic cells is a challenging approach. The extracellular matrix component fibronectin has been known to modulate the cell cycle dynamics, viability and differentiation of leukaemia cells. Thus, ... -
Çağın Devleti ve Şiddet
(Sosyal Bilimler Enstitüsü, 2020-01)This dissertation aims to question an important promise that the modern state guarantees the protection of human rights, in return of a voluntary transfer of natural rights of people to the sovereign power, for the sake ... -
Ubiquitination And Regulation Of Aurka Identifies A Hypoxia-Independent E3 Ligase Activity Of Vhl
(Nature Publishing Group, 2017)The hypoxia-regulated tumor-suppressor von Hippel-Lindau (VHL) is an E3 ligase that recognizes its substrates as part of an oxygen-dependent prolyl hydroxylase (PHD) reaction, with hypoxia-inducible factor α (HIFα) being ... -
Vaccination Attitudes Among Patients With Cancer Receiving Chemotherapy
(Akad Doktorlar Yayınevi, 2016)Immunization against vaccine preventable diseases is an essential but mostly overlooked issue in oncology practice. We aimed to investigate the utilization of adult immunization recommendations and the perception of the ... -
What is a Pericyte?
(International Society for Cerebral Blood Flow & Metabolism, 2016)Pericytes, spatially-isolated contractile cells on capillaries, have been reported to control cerebral blood flow physiologically, and to limit blood flow after ischaemia by constricting capillaries and then dying. ... -
Retinitis Pigmentosa Caused By Mutations In The Ciliary Mak Gene Is Relatively Mild And Is Not Associated With Apparent Extra-Ocular Features
(Wiley, 2015)Purpose: Defects in MAK, encoding a protein localized to the photoreceptor connecting cilium, have recently been associated with autosomal recessive retinitis pigmentosa (RP). The aim of this study is to describe our ... -
Prevalence And Risk Factors of Helicobacter Pylori In Turkey: A Nationally-Representative, Cross-Sectional, Screening With The 13C-Urea Breath Test
(Biomed Central, 2013)Background Helicobacter pylori is an important global pathogen infecting approximately 50% of the world’s population. This study was undertaken in order to estimate the prevalence rate of Helicobacter pylori infections ... -
Refractory Lesional Parietal Lobe Epilepsy: Clinical, Electroencephalographic And Neurodiagnostic Findings
(Aves, 2016)Introduction: Specialized centers, in the management and surgical treatment of medically refractory epilepsy, emphasize the importance of differentiating the varieties of localization related epilepsies. There has been ... -
Long-Term Survival Of Patients With Cll After Allogeneic Transplantation: A Report From The European Society For Blood And Marrow Transplantation
(Macmillan Publishers Limited, 2017)Even with the availability of targeted drugs, allogeneic hematopoietic cell transplantation (allo-HCT) is the only therapy with curative potential for patients with CLL. Cure can be assessed by comparing long-term survival ... -
Health-Related Quality Of Life With Regard To Smoking, Consumption Of Alcohol, And Sports Participation
(Kowsar Medical Institute, 2016)Background Health-related quality of life (HRQoL) is an important determinant in a person’s life. Objectives In this study aimed at physical education students, alcohol consumption and smoking as risk factors and sports ...
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