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Nuclear Expansion And Pore Opening Are Instant Signs Of Neuronal Hypoxia And Can Identify Poorly Fixed Brains 

Dehghani, Anisa; Karataş, Hülya; Can, Alp; Erdemli, Esra; Yemişci, Müge; Eren Koçak, Emine; Dalkara, Turgay (Nature Publishing Group, 2018)
The initial phase of neuronal death is not well characterized. Here, we show that expansion of the nuclear membrane without losing its integrity along with peripheralization of chromatin are immediate signs of neuronal ...

Refractory Lesional Parietal Lobe Epilepsy: Clinical, Electroencephalographic and Neurodiagnostic Findings 

Kurşun, Oğuzhan; Karataş, Hülya; Dericioğlu, Neşe; Saygı, Serap (Aves, 2016)
Introduction: Specialized centers, in the management and surgical treatment of medically refractory epilepsy, emphasize the importance of differentiating the varieties of localization related epilepsies. There has been ...

Thrombotic Distal Middle Cerebral Artery Occlusion Produced By Topical Fecl3 Application: A Novel Model Suitable For Intravital Microscopy And Thrombolysis Studies 

Karataş, Hülya; Erdener, Şefik Evren; Gürsoy Özdemir, Yasemin; Gürer, Günfer; Söylemezoğlu, Figen; Dunn, Andrew K.; Dalkara, Turgay (Nature Publishing Group, 2011)
Intravital or multiphoton microscopy and laser-speckle imaging have become popular because they allow live monitoring of several processes during cerebral ischemia. Available rodent models have limitations for these ...

Improving Microcirculatory Reperfusion Reduces Parenchymal Oxygen Radical Formation And Provides Neuroprotection 

Taşkıran, Aslıhan; Yemişçi Özkan, Müge; Özdemir, Yasemin; Erdener, Sefik Evren; Karataş, Hülya; Yüce, Deniz; Dalkara, Turgay (Lippincott Williams & Wilkins, 2018)
Background and Purpose-Reperfusion is the most significant determinant of good outcome after ischemic stroke. However, complete reperfusion often cannot be achieved, despite satisfactory recanalization. We hypothesized ...

Inadequate Brain Glycogen Or Sleep Increases Spreading Depression Susceptibility 

Kılıç, Kıvılcım; Karataş, Hülya; Dönmez Demir, Buket; Eren Koçak, Emine; Gürsoy Özdemir, Yasemin; Can, Alp; Petit, Jean-Marie; Magistretti, Pierre J.; Dalkara, Turgay (Wiley, 2018)
Objective: Glycogen in astrocyte processes contributes to maintenance of low extracellular glutamate and K+ concentrations around excitatory synapses. Sleep deprivation (SD), a common migraine trigger, induces transcriptional ...

Inhibiting 12/15-Lipoxygenase To Treat Acute Stroke In Permanent And Tpa Induced Thrombolysis Models 

Karataş, Hülya; Leyen, Klaus van; |Jung, Joo Eun; Lo, E. H. (Elsevier Science Bv, 2018)
12/15-Lipoxygenase (12/15-LOX) contributes to the brain damage after middle cerebral artery occlusion (MCAO) in the acute phase of stroke. The aim of this study was to investigate the effects of a 12/15-LOX inhibitor, ...
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Karataş, Hülya (6)
Dalkara, Turgay (4)Can, Alp (2)Eren Koçak, Emine (2)Gürsoy Özdemir, Yasemin (2)Dehghani, Anisa (1)Dericioğlu, Neşe (1)Dunn, Andrew K. (1)Dönmez Demir, Buket (1)Erdemli, Esra (1)... View MoreSubjectNöroloji (4)Neurosciences & neurology (3)Tıp (2)Aura (1)Cardiovascular system & cardiology (1)EEG (1)Epilepsy (1)Focal ischemia (1)Intravital microscopy (1)Laser-speckle imaging (1)... View MoreDate Issued2018 (4)2011 (1)2016 (1)Has File(s)Yes (6)

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