Enstitüler: Recent submissions
Now showing items 1-20 of 395
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Prognostic Significance of Notch1 and Fbxw7 Mutations in Pediatric T-All
(Hindawi Ltd, 2010)The NOTCH signaling pathway plays important role in the development of multicellular organisms, as it regulates cell proliferation, survival, and differentiation. In adults, it is essential for the T- or B-lymphocyte lineage ... -
COMPARATIVE ANALYSIS OF NONCOMMUNICABLE DISEASES AND THEIR RISK FACTORS AMONG SYRIAN REFUGEES IN TURKEY AND TURKISH POPULATION
(Nüfus Etütleri Enstitüsü, 2020-02-25)Turkey is the host to the highest number of refugees hosted by a country. This huge number of refugee population, fleeing from ongoing conflict in their country of origin to Turkey, brought together the concern for ... -
The Association Between Body Mass Index and Immunohistochemical Subtypes in Breast Cancer
(Elsevier, 2017)Background:Body mass index (BMI) is defined as a poor prognostic factor in patients with breast cancer(BC). However, there are controversial results regarding the various effects of BMI on BC, hence the exactpathophysiology ... -
Targeted Therapies in Gastric Cancer and Future Perspectives
(Baishideng Publishing Group Inc, 2016)Advanced gastric cancer (AGC) is associated with a high mortality rate and, despite multiple new chemotherapy options, the survival rates of patients with AGC remains poor. After the discovery of targeted therapies, research ... -
Tamoxifen-Induced Tissue Factor Pathway Inhibitor Reduction: A Clue for an Acquired Thrombophilic State?
(Oxford Univ Press, 2004)Background: Current understanding of hemostatic systems enables us to better explore the enigmatic pathobiology of tamoxifen (TAM)-induced thrombotic diathesis. We have therefore aimed to assess the hemostatic changes in ... -
Successful Treatment of Intracaval and Atrial Extension of Wilms' Tumour by Chemotherapy
(British Med Journal Publ Group, 1996)A patient presenting with advanced Wilms' tumour was diagnosed as having inferior vena cava involvement with tumour thrombus extending up to the right atrium, and was treated with preoperative chemotherapy (vincristine, ... -
Stereotactic Re-Irradiation For Recurrent Or Second Primary Head-And-Neck Cancer
(The Official Journal of Turkish Society for Radiation Oncology, 2018)Local recurrence after definitive radiotherapy for advanced head-and-neck cancer is observed in 30%– 60% of the patients. Surgical resection is possible in only about 25% of the cases. Re-irradiation for local recurrence ... -
Spontaneous Thrombosis of Significant Aneurysm Recanalization in the Long Term Follow-Up of Coiled Aneurysms - Observation in Two Cases
(Edizioni Centauro, 2005)Endovascular treatment of cerebral aneurysms with detachable coils has now been proved to be a superior alternative to open microsurgery in terms of survival free of disability at one year according to the recently published ... -
Türkiye’ye Eğitim Amaçlı Gelen Uluslararası Çinli Öğrencilerin Sosyal Bütünleşmeleri
(Sosyal Bilimler Enstitüsü, 2020-01-24)In recent years, between Turkey and China economic and trade relations have been increasing. It can be said that Turkey's "Central Corridor initiative’’ and China's "Silk Road Economic Belt and 21. Century sea route Silk ... -
Smooth Muscle Cells Isolated from Thoracic Aortic Aneurysms Exhibit Increased Genomic Damage, but Similar Tendency for Apoptosis
(Mary Ann Liebert Inc, 2012)Aortic aneurysms (AA) are characterized by structural deterioration leading to progressive dilation. During the development of AA, two key structural changes are pronounced, one being degradation of extracellular matrix ... -
Smoking Induces Coordinated Dna Methylation and Gene Expression Changes in Adipose Tissue with Consequences for Metabolic Health
(Springer Nature, 2018)Background: Tobacco smoking is a risk factor for multiple diseases, including cardiovascular disease and diabetes. Many smoking-associated signals have been detected in the blood methylome, but the extent to which ... -
Smoking Habits of Relatives of Patients with Cancer: Cancer Diagnosis in the Family is an Important Teachable Moment for Smoking Cessation
(Asian Pacific Organization Cancer Prevention, 2013)Background: In this study we aimed to determine the rate and habitual patterns of smoking, intentions of cessation, dependence levels and sociodemographic characteristics of relatives of patients with a diagnosis of cancer. ... -
Single Institution Experience on Cancer Among Adolescents 15-19 Years of Age
(Turkish J Pediatrics, 2017)Adolescent cancers differ from other age groups in terms of cancer types, treatment and outcome. We aimed to present our institutional data on survival of certain types of cancer in adolescents. Hospital files were ... -
Short-Hairpin Rna Silencing Of Endogenous Fibroblast Growth Factor 2 In Rat Hippocampus Increases Anxiety Behavior
(Elsevier Science Inc, 2011)Background: The fibroblast growth factor system has been implicated in the pathophysiology of mood disorders in humans and in affective behavior in animal models. However, the studies have been either correlative or involved ... -
The Neurophysiologic Frequency Of Hereditary Neuropathy With Liability To Pressure Palsy In Entrapment Neuropathies
(Türk Nöroloji Derneği, 2016)"Objective: Hereditary neuropathy with liability to pressure palsy (HNPP) needs to be differentiated from entrapment neuropathies due to differences in the treatment management. Materials and Methods: Among 5075 patients ... -
Serum 25-Hydroxy Vitamin D Status Is Not Related To Osteopenia/Osteoporosis Risk In Colorectal Cancer Survivors
(Asian Pacific Organization Cancer Prevention, 2014)Background: The incidence of colorectal cancer increases with vitamin D deficiency as shown in recently published studies. In addition, prospective investigations have indicated that low vitamin D levels may be associated ... -
The Relationship of Agmatine Deficiency with the Lung Cancer
(Akad Doktorlar Yayınevi, 2016)The polyamines are essential for rapidly growing cells. Polyamines is synthesized by two reactions which begin from arginine. The aim of this study is to examine the serum levels of the enzymes located in the putrescine ... -
MEZENKİMAL KÖK HÜCRE ÜRETİMİNDE İN VİTRO TEMELLİ METABOLOMİK VE ANALİZLER
(Sağlık Bilimleri Enstitüsü, 2020-02-12)Karaağaç Akyol, T. Metabolomic And Analyzes In In-Vitro Based On The Production Of Mesenchimal Stem Cells, Hacettepe University Graduate School of Health Sciences Stem Cells Program Doctor of Philosophy Thesis, Ankara, ... -
Thrombotic Distal Middle Cerebral Artery Occlusion Produced By Topical Fecl3 Application: A Novel Model Suitable For Intravital Microscopy And Thrombolysis Studies
(Nature Publishing Group, 2011)Intravital or multiphoton microscopy and laser-speckle imaging have become popular because they allow live monitoring of several processes during cerebral ischemia. Available rodent models have limitations for these ... -
Transfection Of Myeloid Leukaemia Cell Lines Is Distinctively Regulated By Fibronectin Substratum
(Springer, 2009)Gene transfer into haematopoietic cells is a challenging approach. The extracellular matrix component fibronectin has been known to modulate the cell cycle dynamics, viability and differentiation of leukaemia cells. Thus, ...
