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Transfection Of Myeloid Leukaemia Cell Lines Is Distinctively Regulated By Fibronectin Substratum
(Springer, 2009)Gene transfer into haematopoietic cells is a challenging approach. The extracellular matrix component fibronectin has been known to modulate the cell cycle dynamics, viability and differentiation of leukaemia cells. Thus, ... -
Ubiquitination And Regulation Of Aurka Identifies A Hypoxia-Independent E3 Ligase Activity Of Vhl
(Nature Publishing Group, 2017)The hypoxia-regulated tumor-suppressor von Hippel-Lindau (VHL) is an E3 ligase that recognizes its substrates as part of an oxygen-dependent prolyl hydroxylase (PHD) reaction, with hypoxia-inducible factor α (HIFα) being ... -
Vaccination Attitudes Among Patients With Cancer Receiving Chemotherapy
(Akad Doktorlar Yayınevi, 2016)Immunization against vaccine preventable diseases is an essential but mostly overlooked issue in oncology practice. We aimed to investigate the utilization of adult immunization recommendations and the perception of the ... -
Long-Term Survival Of Patients With Cll After Allogeneic Transplantation: A Report From The European Society For Blood And Marrow Transplantation
(Macmillan Publishers Limited, 2017)Even with the availability of targeted drugs, allogeneic hematopoietic cell transplantation (allo-HCT) is the only therapy with curative potential for patients with CLL. Cure can be assessed by comparing long-term survival ... -
Psoriasiste Lipocalin 2 Spesifik Reseptörünün Immünohistokimyasal Olarak Saptanması
(2015)Amaç: Serum Lipokalin 2 (LCN2) seviyelerinin psoriasiste artmış inflamasyon için bir genel belirteç olduğu bilinmektedir. Bu çalışmada, LCN2’nin psoriatik lezyonlardaki reseptör düzeyini araştırmayı amaçladık. Yöntemler: ... -
Immunohistochemical Expression of Insulin-Like Growth Factor-1, Transforming Growth Factor-Beta1, and Vascular Endothelial Growth Factor In Parathyroid Adenoma and Hyperplasia
(Medknow Publications & Media Pvt Ltd, 2014)Background: Insulin-like growth factor (IGF), transforming growth factor-beta1 (TGF-beta 1), and vascular endothelial growth factor (VEGF) are commonly studied growth factors, but little data are available on the ... -
Good Outcomes Of Patients With Stage Ib Endometrial Cancer With Surgery Alone
(Asian Pacific Organization Cancer Prevention, 2014)Background: Most patients with endometrial cancer have stage I disease. Adjuvant therapy in stage IB (formerly IC) endometrial cancer is controversial, treatment options including observation or brachytherapy/radiotherapy ... -
Higher Ki67 Expression Is Associates With Unfavorable Prognostic Factors And Shorter Survival In Breast Cancer
(Asian Pacific Organization Cancer Prevention, 2014)Background: The prognostic value of the Ki67 expression level is yet unclear in breast cancer. The aim of this study was to investigate the association between Ki67 expression levels and prognostic factors such as grade, ... -
Impact Of Adjuvant Chemoradiotherapy For Rectal Cancer On The Long-Term Quality Of Life And Late Side Effects: A Multicentric Clinical Evaluation By The Turkish Oncology Group
(Asian Pacific Organization Cancer Prevention, 2012)Aim: Although preoperative chemoradiatherapy (CRT) has proven its benefits in terms of decreased toxicity, there is still a considerable amount of cases that do not receive postoperative CRT. Oncologists at different ... -
Impact Of Acetylsalicylic Acid On The Clinicopathological Characteristics And Prognosis Of Patients With Invasive Breast Cancer
(Karger, 2014)Background: The impact of acetylsalicylic acid (ASA) on the clinicopathological characteristics of breast cancer has not yet been elucidated in detail; we therefore aimed to investigate the effects of ASA on the ... -
Metastatic Germ Cell Tumor Presenting With Renovascular Hypertension
(Karger, 1996) -
Deep Vein Thrombosis Following Non-Myeloablative Allogeneic Stem Cell Transplantation: Presentation of Three Cases and Literature Review
(Galenos Yayınevi, 2013)The incidence of deep vein thrombosis (DVT) after non-myeloablative (NMA) allogeneic stem cell transplantation (allo-SCT) is unknown. In addition, very few studies on the predisposing factors for DVT post SCT have been ... -
Cytoreductive Surgery For Intestinal Cancer Patients Metastatic To Ovaries Presenting As Primary Ovarian Cancer
(Akad Doktorlar Yayinevi, 2016)Colorectal cancer accounts for one third of non-genital tumors metastasize to the ovaries. We aimed to investigate the role of cytoreductive surgery in colon and small intestinal cancer patients with adnexal metastases, ... -
Obesity Is An Independent Prognostic Factor Of Decreased Pathological Complete Response To Neoadjuvant Chemotherapy In Breast Cancer Patients
(Elsevier, 2017)PURPOSE: The relation between higher body mass index (BMI) and pathological complete response (pCR) to neoadjuvant chemotherapy (NAC) in breast cancer (BC) is a controversial issue according to the data of Western and ... -
Efficacy of Sorafenib In Advanced Differentiated and Medullary Thyroid Cancer: Experience In A Turkish Population
(Dove Press, 2014)Purpose: Chronic otitis media with effusion (OME) is the leading cause of hearing loss during childhood. In bacterial etiology of OME, the most frequent pathogens responsible are Haemophilus influenzae followed by Streptococcus ... -
Mean Esophageal Radiation Dose Is Predictive of The Grade of Acute Esophagitis in Lung Cancer Patients Treated with Concurrent Radiotherapy And Chemotherapy
(Oxford University, 2012)The intention of this research was to define the predictive factors for acute esophagitis (AE) in lung cancer patients treated with concurrent chemotherapy and three-dimensional conformal radiotherapy. The data for 72 lung ... -
Efficacy of Adjuvant Aromatase Inhibitor In Hormone Receptor-Positive Postmenopausal Breast Cancer Patients According To The Body Mass Index
(Cancer Research UK, 2012)Background: Increased adiposity may trigger signalling pathways that induce aromatase expression. As aromatase inhibitors exert their effects by blocking the aromatase enzyme, higher body mass index (BMI) can reduce the ... -
Molecular Demultiplexer As A Terminator Automaton
(Nature Communication, 2018)Molecular logic gates are expected to play an important role on the way to information processing therapeutic agents, especially considering the wide variety of physical and chemical responses that they can elicit in ... -
Determinants of New-Onset Atrial Fibrillation in Patients Receiving Crt Mechanistic Insights From Speckle Tracking Imaging
(Elsevier Science Inc, 2016)OBJECTIVES The aim of this study was to investigate the factors associated with the development of atrial fibrillation (AF) and to examine the impact of these factors for long-term outcome after cardiac resynchronization ... -
Lack Of Relationships Between Fgf19 Staining Pattern, Lymph Node Metastasis And Locally Invasive Characteristics Of The Tumor In Colorectal Cancers
(Asian Pacific Organization Cancer Prevention, 2013)Introduction: Colorectal cancers are in the top of the cancer-related causes of death in the world and lymph node metastasis is accepted as the primary prognostic factor. In this study, correlations of FGF19 staining pattern ...
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