Browsing Kanser Enstitüsü by Title
Now showing items 1-20 of 43
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3 Boyutlu Baskı Teknolojisi Kullanılarak Hastaya Özgün Konturlarla Oluşturulan Fantom Tasarımı ve Üretimi ile Mikro-Çok Yapraklı Kolimatör Tabanlı Beyin ve Başboyun Yoğunluk Ayarlı Radyoterapi Planlarının Kalite Kontrolü
(Sağlık Bilimleri Enstitüsü, 2017)SUNEL, S. Quality control of micro-multileaf collimator based brain and head-and-neck intensity modulated radiotherapy plans with patient-specific phantom design and production using 3D printing technology. Hacettepe ... -
3′End Maturation of Human Telomerase Rna Component (Terc) and Its Effects on Telomere Dynamics
(Sağlık Bilimleri Enstitüsü, 2017-09-15)Telomerase RNA Component (TERC) is the non-coding RNA template and scaffold of the telomerase holoenzyme. TERC level has been shown to be a limiting factor for telomerase activity, lower levels resulting in telomere diseases ... -
Adjuvan Radyoterapi Planlanan Jinekolojik Kanserli Olgularda Radyoterapi Sırasındaki Kilo Değişiklikleri ve Organ Hareketlerine Bağlı Dozimetrik Değişikliklerin İncelenmesi
(Kanser Enstitüsü, 2014)In this study, planned curative surgery and postoperative adjuvant radiotherapy (RT), 10 patient with gynecological tumors taken for planning purposes at the beginning of treatment with computed tomography (CT) taken in ... -
Akciğer Kanserlerinde Stereotaktik Ablatif Beden Radyoterapisinin Toksisite ve Doz - Yanıt İlişkisinin Matematiksel Model ile Görüntü ve Dozimetrik Analizi
(Kanser Enstitüsü, 2017-02-17)In conventional radiotherapy applications, clinicians and physicist rely upon mathematical dose - response models for applied doses to tumor and periphery healthy tissues. However in stereotactic ablative body radiotherapy ... -
All-Trans Retinoik Asit (Atra) ve 1Α,25-Dihidroksivitamin D3 (Vitamin D3) ile Uyarılan Akut Miyeloid Lösemi Hücrelerinin T Hücre Yanıtları Üzerine Etkisi
(Kanser Enstitüsü, 2014)ATRA and D3 are the active metabolites of vitamin A and D, respectively. In this study, HL-60 myeloid leukemia cells were progressed through different maturation stages with ATRA, D3, LPS, and IFN-γ. For the determination ... -
CXCL KEMOKİN ÖNCÜL DİZELERİNDEN TÜREVLENEN KÜÇÜK PEPTİT MOLEKÜLLERİNİN İMMÜN DÜZENLEYİCİ ETKİSİNİN DEĞERLENDİRİLMESİ
(Kanser Enstitüsü, 2019-03-12)Peptide structured small molecules function in the regulation of a variety of physiological processes and intercellular communication. In this study, precursor sequences of known 17 CXCL chemokine molecules were analyzed ... -
Cyberknife Synchrony® Solunum Takip Sisteminin Polimer Jel Dozimetre ile Üç Boyutlu Performans Analizi
(Kanser Enstitüsü, 2017-02-20)ŞAHİN, M. C. Three Dimensional Performance Analysis Of Cyberknife Synchrony® Respiratory Tracking System Using Polymer Gel Dosimeter. Hacettepe University Institute of Health Sciences, Thesis in Radiotherapy Physics ... -
CyberKnife® Robotik Radyocerrahi Cihazında MAGIC Polimer Jel Dozimetre İle Küçük Alan Dozimetrisinin İncelenmesi
(Kanser Enstitüsü, 2018)ENKAVİ, M.F. Investigation of Small Field Dosimetry with MAGIC Polymer Gel Dosimeter in CyberKnife® Robotic Radiosurgery Device. Hacettepe University Institute of Health Sciences, MSc. Thesis in Radiotherapy Physics Program, ... -
Cyberknife® X-Sight® Vertebra Takip Sisteminin Vertebra Dışı Lezyonlarda Uygulanabilirliğinin Araştırılması
(Kanser Enstitüsü, 2017-03-25)One of devices which uses the ablative dose for the Stereotactik body radiation theraphy (SBRT) is CyberKnife® Stereotactic Radiosurgery System. This device, has different tracking system from other devices. This systems ... -
Çinko Katkılanmış Hidroksiapatit Nanoparçacıklarının Kanser Hücrelerinin Radyoduyarlılığına Etkisi
(Sağlık Bilimleri Enstitüsü, 2019-04-09)Yedekçi, F.Y., Effect Of Zinc Doped Hydroxyapatite Nanoparticles On Radiosensitivity Of Cancer Cells, Hacettepe University, Graduate School of Health Sciences, Radiation Therapy Physics, Doctor of Philosophy Thesis, Ankara, ... -
Effect of Calcıum Carbonate Encapsulatıon on the Oral Actıvıty of Cpg Olıgodeoxynucleotıdes and Assessment of the Response of Human Monocytes to Tlr Lıgands
(Sağlık Bilimleri Enstitüsü, 2018-03)Toll-like receptor (TLR) ligands modulate immune responses and have been used in immunotherapy. Clinical trials designed to evaluate the utility of CpG ODN, a synthetic TLR9 ligand, relied on parenteral routes of administration. ... -
Evaluation of Metadherin Expression in Breast Cancer
(Sağlık Bilimleri Enstitüsü, 2018)Metadherin gene (MTDH/ AEG-1/ Lyric) encodes a 582- aminoacid protein, metadherin (MTDH), which is almost undetectable by immunohistochemistry in normal breast tissue. MTDH expression is markedly increased in breast cancer ... -
Evaluation of T Cell Responses In The Co-Cultures Establıshed Wıth Neutrophıls, Monocytes, and Lung Adenocarcınoma Cells
(Kanser Enstitüsü, 2019)CD4+ and CD8+ T cells are critical mediators in anti-tumor immunity. Together with neutrophils, they have been shown to dominate the immune landscape of the non-small cell lung cancer (NSCLC). A number of studies have ... -
Expressıon and Functıonal Analysıs of Ccrl2 Atypıcal Chemokıne Receptor Varıants on Breast Cancer Cells
(Kanser Enstitüsü, 2014)The complex network of chemokines and chemokine receptors is regulated by atypical (decoy) chemokine receptors. Atypical chemokine receptors play role in the termination of inflammatory responses and CCRL2 is the newest ... -
Expressıon of Toll Lıke Receptors in Lung Cancer and Investıgatıng Theır Effect on Apoptosıs
(Kanser Enstitüsü, 2014)Members of the Toll like receptors (TLRs) family play key roles in both innate and adoptive immune responses. TLRs proteins enable host to recognize a large number of pathogen associated molecular patterns such as bacterial ... -
Gastrointestinal Sistem Kanserli Hastalarda Mide Doluluğunun Radyoterapiye Etkisi
(Kanser Enstitüsü, 2017)In the treatment of gastrointestinal system (GIS) cancers, radiotherapy (RT) is frequently applied as three dimensional conformal RT (3BKRT) or intensity adjusted RT (YART). GIS tumors are very sensitive to environmental ... -
GENİŞLETİLMİŞ BİLGİSAYARLI TOMOGRAFİ SKALASI VE METAL ARTEFAKT AZALIMI YÖNTEMLERİNİN İMPLANTLI HASTALARDA DOZ DAĞILIMINA ETKİSİNİN BİREYSELLEŞTİRİLMİŞ FANTOMLAR KULLANILARAK ANALİZ EDİLMESİ
(Kanser Enstitüsü, 2019-09)Analysis of The Effects of Extended Computed Tomography Scale and Metal Artefact Reduction Methods on Dose Distribution of Patient with Implant by Using Individualized Fantoms. Hacettepe University Graduated School of ... -
Helikal Tomoterapi ile Prostat Işınlamalarında Kritik Organ Dozlarının Cihaz İçi Parametrelere göre Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2017)The treatment planning of Tomotherapy depends on three device parameters, i.e. field width (FW), pitch (P) and modulation factor (MF). Various treatment plans can be generated with different combinations of these parameters. ... -
Inhibition of Serum and Glucocortıcoıd Inducible Kinase 1 (Sgk1) in Triple Negative Breast Cancer
(Kanser Enstitüsü, 2018-07-18)Glucocorticoid receptor overexpression leads to poor prognosis in breast cancer, particularly in triple negative phenotype. This poor prognosis has been shown to be due to the activation of SGK1 (serum and glucocorticoid ... -
INTERACTION MECHANISMS BETWEEN SMALL CELL LUNG CANCER CELLS AND T LYMPHOCYTES
(Kanser Enstitüsü, 2019-08)Tumors are capable of reshaping their microenvironment to escape from immune destruction. For this purpose, tumor cells initiate an immune regulatory program that is typically used by the normal cells to mitigate ...
