Browsing Nörolojik Bilimler ve Psikiyatri Enstitüsü by Title
Now showing items 20-35 of 35
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Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis In Two Pairs Of Identical Twins
(Comenius Univ, 2012)The most common pathology in adult patients with temporal lobe epilepsy is hippocampal sclerosis (HS), the etiology of which is not clear. There is a conflicting evidence in literature regarding whether HS is genetic or ... -
Mitochondrial Dna Analysis In The Turkish Leber'S Hereditary Optic Neuropathy Population
(Royal Coll Ophthalmologists, 2001)Purpose To define the prevalence of a panel of mitochondrial DNA (mtDNA) mutations associated with Leber's hereditary optic neuropathy (LHON) in the Turkish LHON population. LHON-associated mtDNA mutations have been found ... -
MOLECULAR MOTOR CONTRACTILE MECHANISM OF RETINAL PERICYTES
(Nörolojik Bilimler ve Psikiyatri Enstitüsü, 2020)Although it is known that capillary pericytes function in the regulation of capillary tone and blood flow, the contractile proteins involved in these processes are unidentified. It is likely that α-SMA functions as a part ... -
Mutation Analysis Of The Pink1 Gene In 391 Patients With Parkinson Disease
(Amer Medical Assoc, 2008)Objectives: To determine the frequency, distribution, and clinical features of Parkinson disease (PD) with PINK1 mutations. Design: Retrospective clinical and genetic review. Setting: University hospital. Patients: We ... -
Mutations In A Human Robo Gene Disrupt Hindbrain Axon Pathway Crossing And Morphogenesis
(Amer Assoc Advancement Science, 2004)The mechanisms controlling axon guidance are of fundamental importance in understanding brain development. Growing corticospinal and somatosensory axons cross the midline in the medulla to reach their targets and thus form ... -
Neuro-Ophthalmologic Findings In Humans With Quadrupedal Locomotion
(Informa Healthcare, 2012)Purpose: To report the neuro-ophthalmologic findings in four patients from the same family with cerebellar ataxia, mental retardation, and dysequilibrium syndrome (CAMRQ) 2 associated with quadrupedal locomotion. Method: ... -
Nuclear Expansion And Pore Opening Are Instant Signs Of Neuronal Hypoxia And Can Identify Poorly Fixed Brains
(Nature Publishing Group, 2018)The initial phase of neuronal death is not well characterized. Here, we show that expansion of the nuclear membrane without losing its integrity along with peripheralization of chromatin are immediate signs of neuronal ... -
Parenchymal Neuroinflammation in Familial Hemiplegic Migraine Type 1 Transgenic Mouse Model After Cortical Spreading Depression
(Nörolojik Bilimler ve Psikiyatri Enstitüsü, 2019-01)Cortical spreading depression (CSD) is the likely cause of the migraine aura. CSD causes a signaling pathway between stressed neurons and trigeminal afferents via transient opening of neuronal Pannexin-1 (Panx1) mega-channels ... -
Plasma Glycine and Serine Levels in Schizophrenia Compared to Normal Controls and Major Depression: Relation to Negative Symptoms
(Oxford Univ Press, 2004)Previous Studies have suggested decreased N-methyl-D-aspartate (NMDA)-type glutamate receptor function may contribute to increased negative symptoms in patients with schizophrenia. Consistent with this hypothesis, glycine, ... -
Prefrontal Kortekste NUDT6 İfadesindeki Değişikliklerin Sıçanda Depresyon-Benzeri ve Anksiyete-Benzeri Davranışa Etkileri
(Nörolojik Bilimler ve Psikiyatri Enstitüsü, 2018-06-12)Hökelekli, F.Ö. The Effects of NUDT6 Expression Changes in Prefrontal Cortex on Depression- and Anxiety-like Behaviour in Rats, Hacettepe University, Graduate School of Health Sciences PhD thesis in Basic Neurological ... -
Psikolojik Stres İle Kortikal Yayılan Depresyon Uyarılma Eşiği İlişkisi ve İlgili Mekanizmaları
(Nörolojik Bilimler ve Psikiyatri Enstitüsü, 2013)Migraine is suggested to belinked to cortical spreading depression (CSD), thus CSD is used to model migraine inexperimental animals. Migraine is frequently comorbid with depression and anxiety,two disorders that are ... -
Refractory Lesional Parietal Lobe Epilepsy: Clinical, Electroencephalographic and Neurodiagnostic Findings
(Aves, 2016)Introduction: Specialized centers, in the management and surgical treatment of medically refractory epilepsy, emphasize the importance of differentiating the varieties of localization related epilepsies. There has been ... -
Short-Hairpin Rna Silencing Of Endogenous Fibroblast Growth Factor 2 In Rat Hippocampus Increases Anxiety Behavior
(Elsevier Science Inc, 2011)Background: The fibroblast growth factor system has been implicated in the pathophysiology of mood disorders in humans and in affective behavior in animal models. However, the studies have been either correlative or involved ... -
The Neurophysiologic Frequency Of Hereditary Neuropathy With Liability To Pressure Palsy In Entrapment Neuropathies
(Türk Nöroloji Derneği, 2016)"Objective: Hereditary neuropathy with liability to pressure palsy (HNPP) needs to be differentiated from entrapment neuropathies due to differences in the treatment management. Materials and Methods: Among 5075 patients ... -
Thrombotic Distal Middle Cerebral Artery Occlusion Produced By Topical Fecl3 Application: A Novel Model Suitable For Intravital Microscopy And Thrombolysis Studies
(Nature Publishing Group, 2011)Intravital or multiphoton microscopy and laser-speckle imaging have become popular because they allow live monitoring of several processes during cerebral ischemia. Available rodent models have limitations for these ... -
What is a Pericyte?
(International Society for Cerebral Blood Flow & Metabolism, 2016)Pericytes, spatially-isolated contractile cells on capillaries, have been reported to control cerebral blood flow physiologically, and to limit blood flow after ischaemia by constricting capillaries and then dying. ...
