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Glikojen Döngüsünün Bozulmasının Kortikal Yayılan Depolarizasyon Oluşumu ve Panneksin 1 Kanalları Üzerine Etkisinin Araştırılması
(Nörolojik Bilimler ve Psikiyatri Enstitüsü, 2013)
Migraine is an episodic neurological disorder that affects 10-20 % of general population. Cortical spreading depression (CSD) is proposed as the mechanism of migraine aura and the downstream trigeminal activation as the ...
Capillary Pericytes Express Α-Smooth Muscle Actin, Which Requires Prevention of Filamentous-Actin Depolymerization For Detection
(eLife Sciences, 2018)
Recent evidence suggests that capillary pericytes are contractile and play a crucial role in the regulation of microcirculation. However, failure to detect components of the contractile apparatus in capillary pericytes, ...
Inadequate Brain Glycogen Or Sleep Increases Spreading Depression Susceptibility
Objective: Glycogen in astrocyte processes contributes to maintenance of low extracellular glutamate and K+ concentrations around excitatory synapses. Sleep deprivation (SD), a common migraine trigger, induces transcriptional ...