Corticospinal excitability may be affected by various sensory inputs under physiological conditions. Studies about the connection and interaction between the primary motor cortex and these cortical sensory areas indicate ...

Migraine is suggested to belinked to cortical spreading depression (CSD), thus CSD is used to model migraine inexperimental animals. Migraine is frequently comorbid with depression and anxiety,two disorders that are ...

Hökelekli, F.Ö. The Effects of NUDT6 Expression Changes in Prefrontal Cortex on Depression- and Anxiety-like Behaviour in Rats, Hacettepe University, Graduate School of Health Sciences PhD thesis in Basic Neurological ...

Cortical spreading depression (CSD) is not just an experimental phenomenon, but also seen in the conditions such as migraine aura, ischemic stroke, acute brain trauma, intracranial hemorrhage and epilepsy in people. It has ...

Neuroinflammation has been shown to be involved in pathological conditions like cortical spreading depression, seizures and ischemia. Its involvement in physiological processes like neurogenesis, learning and memory has ...

Cortical spreading depression (CSD) is the likely cause of the migraine aura. CSD causes a signaling pathway between stressed neurons and trigeminal afferents via transient opening of neuronal Pannexin-1 (Panx1) mega-channels ...

Migraine is an episodic neurological disorder that affects 10-20 % of general population. Cortical spreading depression (CSD) is proposed as the mechanism of migraine aura and the downstream trigeminal activation as the ...

Migraine is a primary headache disorder with an annual prevalence of 12-15% in the general population, causing considerable disability and productivity loss. Migraine aura is associated with cortical spreading depression (CSD) ...

For most of the neurological diseases, new theurapeutic targets and drugs are needed. During the last several years one of the large pore channels, Pannexin (Panx) channels have emerged as an important target for neurological ...