Uzay B. Investigation of the Subcortical Spreading Mechanisms of the Optogenetically Induced Cortical Spreading Depression in Mice, Hacettepe University Graduate School of Health Sciences Basic Neurological Sciences ...

Hökelekli, F.Ö. The Effects of NUDT6 Expression Changes in Prefrontal Cortex on Depression- and Anxiety-like Behaviour in Rats, Hacettepe University, Graduate School of Health Sciences PhD thesis in Basic Neurological ...

Neuroinflammation has been shown to be involved in pathological conditions like cortical spreading depression, seizures and ischemia. Its involvement in physiological processes like neurogenesis, learning and memory has ...

Migraine is an episodic neurological disorder that affects 10-20 % of general population. Cortical spreading depression (CSD) is proposed as the mechanism of migraine aura and the downstream trigeminal activation as the ...

For most of the neurological diseases, new theurapeutic targets and drugs are needed. During the last several years one of the large pore channels, Pannexin (Panx) channels have emerged as an important target for neurological ...

Migraine is a primary headache disorder with an annual prevalence of 12-15% in the general population, causing considerable disability and productivity loss. Migraine aura is associated with cortical spreading depression (CSD) ...

Migraine is suggested to belinked to cortical spreading depression (CSD), thus CSD is used to model migraine inexperimental animals. Migraine is frequently comorbid with depression and anxiety,two disorders that are ...

Background and Purpose For stroke prevention, patients with atrial fibrillation typically receive oral anticoagulation. The commonly used anticoagulant warfarin increases the risk of hemorrhagic transformation (HT) when a ...

Background: Changes in the default mode network (DMN) activity are early features of Alzheimer's disease (AD) and may be linked to AD-specific A beta pathology. Methods: Cognitive profiles; DMN connectivity alterations; ...

The role of the fibroblast growth factor (FGF) system in brain-related disorders has received considerable attention in recent years. To understand the role of this system in neurological and psychiatric disorders, it is ...