Sağlık Bilimleri Enstitüsü
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KEMİK İLİĞİ YAĞ TABAKASINDAN ELDE EDİLEN MEZENKİMAL KÖK HÜCRELERİN KARAKTERİZASYONU VE SUBKUTAN YAĞ VE KEMİK İLİĞİ KÖKENLİ MEZENKİMAL KÖK HÜCRELERİ İLE KARŞILAŞTIRILMASI
(Sağlık Bilimleri Enstitüsü, 2020-09)Bone marrow adipose tissue (BMAT) has different properties than other adipose tissues. Recent studies have shown the effects of bone marrow adipose tissue on development / progression of acute myeloblastic leukemia (AML), ... -
The Effect of Melatonın on Hıppo Sıgnallıng Pathway in Dental Pulp Stem Cells
(Sağlık Bilimleri Enstitüsü, 2020)Dental pulp stem cells (DPSCs) are heterogeneous multipotent adult stem cells with high capacity to differentiate to both neuronal and non-neuronal cell lineage. Hippo pathway regulates diverse cellular processes, including ... -
Uyarılmış Pluripotent Kök Hücrelerin Araştırma Amaçlı Bankalanmasında Standardizasyon ve Kalite Süreci - Bir Uygulama Modeli: “Pedı-Stem”
(Sağlık Bilimleri Enstitüsü, 2020-06-18)Induced pluripotent stem cell (iPSC) is generated by genetic modification of any cell type of the body in laboratory conditions by transferring of embryonic stem cell-like pluripotent properties. iPSC is a cell model that ... -
Spontaneous Thrombosis of Significant Aneurysm Recanalization in the Long Term Follow-Up of Coiled Aneurysms - Observation in Two Cases
(Edizioni Centauro, 2005)Endovascular treatment of cerebral aneurysms with detachable coils has now been proved to be a superior alternative to open microsurgery in terms of survival free of disability at one year according to the recently published ... -
Smoking Induces Coordinated Dna Methylation and Gene Expression Changes in Adipose Tissue with Consequences for Metabolic Health
(Springer Nature, 2018)Background: Tobacco smoking is a risk factor for multiple diseases, including cardiovascular disease and diabetes. Many smoking-associated signals have been detected in the blood methylome, but the extent to which ... -
Mezenkimal Kök Hücre Üretiminde İn Vitro Temelli Metabolomik ve Analizler
(Sağlık Bilimleri Enstitüsü, 2020-02-12)Karaağaç Akyol, T. Metabolomic And Analyzes In In-Vitro Based On The Production Of Mesenchimal Stem Cells, Hacettepe University Graduate School of Health Sciences Stem Cells Program Doctor of Philosophy Thesis, Ankara, ... -
Effects Of Dietary Sepiolite On Performance, Egg Quality And Some Blood Parameters In Laying Hens
(Ankara Univ Press, 2016)The aim of this study was to determine the effects of dietary sepiolite on performance, egg quality, egg yolk cholesterol content and some blood parameters of laying hens during 22 weeks period. For this purpose a total ... -
Effect of Sex on Carcass and Meat Characteristics of New Zealand White Rabbits Aged 11 Weeks
(Assaciation of Animal Production Societies, 2006)This experiment was conducted to determine and compare some characteristics of the meat and carcass of rabbits aged 11 weeks according to sex. In the experiment thirty male and thirty female New Zealand White rabbits were ... -
Fındık Alerjeninin Çapraz Kontaminasyon Yolaklarının Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2020-01-28)Cross-contamination is a major source of hidden allergens in foods and can occur at all food processing stages. The aim of this study was to investigate contamination pathways and the contamination levels of hazelnut ... -
Functionally Conserved Effects of Rapamycin Exposure on Zebrafish
(Spandıdos Publications, 2016)Mechanistic target of rapamycin (mTOR) is a conserved serine/threonine kinase important in cell proliferation, growth and protein translation. Rapamycin, a well‑known anti‑cancer agent and immunosuppressant drug, inhibits ... -
Factors That Influence Recurrent Lumbar Disc Herniation
(Hong Kong Acad Medicine Press, 2017)Introduction: The most common cause of poor outcome following lumbar disc surgery is recurrent herniation. Recurrence has been noted in 5% to 15% of patients with surgically treated primary lumbar disc herniation. There ... -
Archaeogenomic Analysis of The First Steps of Neolithization in Anatolia and The Aegean
(Royal Soc, 2017)The Neolithic transition in west Eurasia occurred in two main steps: the gradual development of sedentism and plant cultivation in the Near East and the subsequent spread of Neolithic cultures into the Aegean and across ... -
Geriatrik Vakalarda Yüksek Frekanslarda İzlenen Hava Kemik Aralığın Geniş Bant Timpanometri ve DPOAE Yanıtlarına Etkisi
(Sağlık Bilimleri Enstitüsü, 2020)Some anatomical, histological, and physiological changes occur in the external and middle ear depending on aging. In this study, we investigated the wideband tympanometry results of elderly people and different old age ... -
Non-Segmental Vitiligo ile HLA Genotipi Ve Oksidatif Stres Arasındaki İlişki
(Sağlık Bilimleri Enstitüsü, 2019)Vitiligo is an autoimmune skin diseases characterized by acquired loss of functional melanocytes. Although the pathogenesis of vitiligo remains poorly understood, oxidative stress and autoimmune disregulations are considered ... -
Ayak Bileği İnversiyon Yaralanmalarında Erken Proprioseptif Eğitimin Reaksiyon Zamanı ve Denge Üzerine Etkisi
(Sağlık Bilimleri Enstitüsü, 2015-10-14)ABSTRACT Yigit, B., The Effects of Early Proprioceptive Training on Reaction Time and Balance in Ankle Inversion Trauma. Institute of Health Sciences, Prostheses- Orthoses and Biomechani Program, Ph.D. Dissertation, ... -
İnfantil Osteopetrozisli Hasta Uyarılmış Pluripotent Kök Hücreleri ile Osteoklast Defektinin Modellenmesi,Osteoklast ve Hematopoietik Niş İlişkisi
(Sağlık Bilimleri Enstitüsü, 2019)Malignant infantile osteopetrosis is an autosomal recessive disorder. The only available treatment is allogeneic hematopoietic stem cell transplantation. The objective of this study was to model hematopoietic niche in ... -
Volumetrik Rinoplasti Konsepti Ve Düşük İle Yüksek Başlangıçlı Lateral Osteotomi Uygulanan Redüksiyon Rinoplasti Hastalarında Karşılaştırılması
(2019-09-18)Burun estetiğinin burundan nefes alma üzerine etkisi, literatürde onlarca yıldır tartışılan bir konudur. Bu konuyu aydınlatmak adına randomize prospektif kontrol bir klinik çalışma planlanmıştır. Burundan nefes alma problemi ... -
Kemik İliği Mezenkimal Kök Hücrelerinde PKNOX2 Proteinin ATM ve RNF8 Proteinleri ile Etkileşimlerinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2019)Donmez, N., Investigation of PKNOX2 Protein Interactions with ATM and RNF8 in Bone Marrow Derived Mesenchymal Stem Cells, Hacettepe University Graduate School Health Sciences Stem Cell Program Master Thesis, Ankara, 2019. ... -
İnsan Göbek Kordon Veni CD146+ Hücrelerin ve Bu Hücrelerden Elde Edilen Matriks Proteinlerinin in vitro Biyofilm Modellerinde Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2019)In the treatment of wounds, the application of cells or decellularized matrices with antimicrobial effects to the wound area has attracted attention in recent years. The aim of this thesis is to evaluate CD146+ stem cells ... -
Characterization of Acute Myeloid Leukemia Stem Cells By Niche-Like Coculture System
(Sağlık Bilimleri Enstitüsü, 2019)AML heterogeneity show evidence of hierarchical cellular organization and at the top of this hierarchical structure there is a rare group of LSCs. It was mentioned that there is an association between LSCs and disease ...