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Metabolom ve Transkriptom Profillemesi ile İnsan Kemik İliğinde Hematopoetik Niş Karakterizasyonu
(Çocuk Sağlığı Enstitüsü, 2015)
In model organisms and animal experiments, it has been shown that hematopoietic stem cells (HSC) in bone marrow have special organizations and they provide this organization through special microenvironment called niche. ...
İnfantil Osteopetrozisli Hasta Uyarılmış Pluripotent Kök Hücreleri ile Osteoklast Defektinin Modellenmesi,Osteoklast ve Hematopoietik Niş İlişkisi
(Sağlık Bilimleri Enstitüsü, 2019)
Malignant infantile osteopetrosis is an autosomal recessive disorder. The only available treatment is allogeneic hematopoietic stem cell transplantation. The objective of this study was to model hematopoietic niche in ...
Ayak Bileği İnversiyon Yaralanmalarında Erken Proprioseptif Eğitimin Reaksiyon Zamanı ve Denge Üzerine Etkisi
(Sağlık Bilimleri Enstitüsü, 2015-10-14)
ABSTRACT
Yigit, B., The Effects of Early Proprioceptive Training on Reaction Time and
Balance in Ankle Inversion Trauma. Institute of Health Sciences, Prostheses-
Orthoses and Biomechani Program, Ph.D. Dissertation, ...
Griscelli Sendromu Uyarılmış Pluripotent Kök Hücre Geliştirilmesi, Karakterizasyonu ve İn Vitro Hematopoetik Farklılaşması
(Sağlık Bilimleri Enstitüsü, 2018-04-04)
Griscelli type 2 Syndrome (GS-2) is a rare, autosomal recessive
immune deficiency syndrome. The RAB27A gene mutation in GS-2 patients results in
the loss of function of T and NK cells. Induced pluripotent stem cells ...
Eritropoetin Uygulamasının Mezenkimal Kök Hücre Gen ifade Profiline Etkisi
(Sağlık Bilimleri Enstitüsü, 2018)
Mesenchymal Stem Cells (MSC) have therapeutic importance because of their multipotency and immune modulation potentials. Erythropoietin is responsible for erytropoesis. However, EPO treatment of cells including mesenchymal ...
Characterization of Acute Myeloid Leukemia Stem Cells By Niche-Like Coculture System
(Sağlık Bilimleri Enstitüsü, 2019)
AML heterogeneity show evidence of hierarchical cellular organization and at the top of this hierarchical structure there is a rare group of LSCs. It was mentioned that there is an association between LSCs and disease ...
İnsan Göbek Kordon Veni CD146+ Hücrelerin ve Bu Hücrelerden Elde Edilen Matriks Proteinlerinin in vitro Biyofilm Modellerinde Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2019)
In the treatment of wounds, the application of cells or decellularized matrices with antimicrobial effects to the wound area has attracted attention in recent years. The aim of this thesis is to evaluate CD146+ stem cells ...
Kemik İliği Mezenkimal Kök Hücrelerinde PKNOX2 Proteinin ATM ve RNF8 Proteinleri ile Etkileşimlerinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2019)
Donmez, N., Investigation of PKNOX2 Protein Interactions with ATM and RNF8 in Bone Marrow Derived Mesenchymal Stem Cells, Hacettepe University Graduate School Health Sciences Stem Cell Program Master Thesis, Ankara, 2019. ...
Mezenkimal Kök Hücrelerin Diamond Blackfan Anemisi Hastalığındaki Rolünün Aydınlatılması
(Sağlık Bilimleri Enstitüsü, 2018-07)
In this thesis, the molecular etiology of Diamond Blackfan Anemia is tried to be enlightened. For this purpose, bone marrow mesenchymal and hematopoietic stem cells from the patients were comparatively analyzed with healthy ...
Değişik Kaynaklı MKH’lerin Detaylı Karakterizasyonu, Lenfohematopoezi Destekleyici Özellikleri ve İzolasyonunda CD271 Antijeninin Önemi
(Sağlık Bilimleri Enstitüsü, 2018)
Mesenchymal Stem Cells (MSCs) are multipotent cells with self-renewal ability and form the basis for regenerative treatments. CD271 antigen is an effective marker for isolation of pure populations of MSCs from bone marrow ...