In model organisms and animal experiments, it has been shown that hematopoietic stem cells (HSC) in bone marrow have special organizations and they provide this organization through special microenvironment called niche. ...

Malignant infantile osteopetrosis is an autosomal recessive disorder. The only available treatment is allogeneic hematopoietic stem cell transplantation. The objective of this study was to model hematopoietic niche in ...

ABSTRACT Yigit, B., The Effects of Early Proprioceptive Training on Reaction Time and Balance in Ankle Inversion Trauma. Institute of Health Sciences, Prostheses- Orthoses and Biomechani Program, Ph.D. Dissertation, ...

Griscelli type 2 Syndrome (GS-2) is a rare, autosomal recessive immune deficiency syndrome. The RAB27A gene mutation in GS-2 patients results in the loss of function of T and NK cells. Induced pluripotent stem cells ...

Mesenchymal Stem Cells (MSC) have therapeutic importance because of their multipotency and immune modulation potentials. Erythropoietin is responsible for erytropoesis. However, EPO treatment of cells including mesenchymal ...

AML heterogeneity show evidence of hierarchical cellular organization and at the top of this hierarchical structure there is a rare group of LSCs. It was mentioned that there is an association between LSCs and disease ...

In the treatment of wounds, the application of cells or decellularized matrices with antimicrobial effects to the wound area has attracted attention in recent years. The aim of this thesis is to evaluate CD146+ stem cells ...

Donmez, N., Investigation of PKNOX2 Protein Interactions with ATM and RNF8 in Bone Marrow Derived Mesenchymal Stem Cells, Hacettepe University Graduate School Health Sciences Stem Cell Program Master Thesis, Ankara, 2019. ...

In this thesis, the molecular etiology of Diamond Blackfan Anemia is tried to be enlightened. For this purpose, bone marrow mesenchymal and hematopoietic stem cells from the patients were comparatively analyzed with healthy ...

Mesenchymal Stem Cells (MSCs) are multipotent cells with self-renewal ability and form the basis for regenerative treatments. CD271 antigen is an effective marker for isolation of pure populations of MSCs from bone marrow ...