Show simple item record

dc.contributor.authorHizarcioglu-Gulsen, Hayriye
dc.contributor.authorYüce, Aysel
dc.contributor.authorAkcoren, Zuhal
dc.contributor.authorBerberoglu-Ates, Burcu
dc.contributor.authorAydemir, Yusuf
dc.contributor.authorSag, Erdal
dc.contributor.authorCeylaner, Serdar
dc.date.accessioned2019-12-10T10:42:35Z
dc.date.available2019-12-10T10:42:35Z
dc.date.issued2014
dc.identifier.issn2192-8304
dc.identifier.urihttps://doi.org/10.1007/8904_2014_335
dc.identifier.urihttp://hdl.handle.net/11655/14243
dc.description.abstractHuman chitinolytic enzyme named "chitotriosidase" takes part in the defense mechanism against pathogens and the homeostasis of innate immunity. Chitotriosidase was firstly reported to be markedly high in plasma of patients with Gaucher disease. Abnormal lipid laden macrophages are thought to be responsible for stimulating the secretion of chitotriosidase in Gaucher disease. Subsequently, various disorders have also been found to be associated with elevated levels of chitotriosidase. Chronic liver diseases that are also related with macrophage activation may have elevated chitotriosidase activity. We report the second case of the literature with glycogen storage disease (GSD) type IV that presented with high chitotriosidase levels. GSD type IV should be taken into consideration in case of elevated chitotriosidase levels, stigmas of chronic liver disease, and inconsistency of lysosomal storage diseases.
dc.language.isoen
dc.publisherSpringer-Verlag Berlin
dc.relation.isversionof10.1007/8904_2014_335
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectEndocrinology & Metabolism
dc.subjectGenetics & Heredity
dc.titleA Rare Cause of Elevated Chitotriosidase Activity: Glycogen Storage Disease Type IV
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/bookPart
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.relation.journalJimd Reports, Vol 17
dc.contributor.departmentÇocuk Sağlığı ve Hastalıkları
dc.identifier.volume17
dc.identifier.startpage63
dc.identifier.endpage66
dc.indexingWoS


Files in this item

This item appears in the following Collection(s)

Show simple item record