Tıp Fakültesi
Recent Submissions
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Targeting Plk1 Overcomes T-Dm1 Resistance Via Cdk1-Dependent Phosphorylation and Inactivation Of Bcl-2/Xl In Her2-Positive Breast Cancer
(Nature Publishing Group, 2018)Trastuzumab-refractory, HER2 (human epidermal growth factor receptor 2)-positive breast cancer is commonly treated with trastuzumab emtansine (T-DM1), an antibody-drug conjugate of trastuzumab and the microtubule-targeting ... -
KOLESTAZ HASTALARINDA SAFRA ASİTLERİNİN LC-MS/MS İLE ARAŞTIRILMASI VE OLASI BİYOBELİRTEÇLERİN BELİRLENMESİ
(Sağlık Bilimleri Enstitüsü, 2020-02-18)Inborn errors of bile acid synthesis (IEBAS) are autosomal recessively inherited disorders that are resulted from the deficiencies in the structure or function of the enzymes involved in the synthesis of bile acids, causing ... -
Measuring Progress From 1990 To 2017 And Projecting Attainment To 2030 Of The Health-Related Sustainable Development Goals For 195 Countries And Territories: A Systematic Analysis For The Global Burden Of Disease Study 2017
(Elsevier Science Inc, 2018)Background Efforts to establish the 2015 baseline and monitor early implementation of the UN Sustainable Development Goals (SDGs) highlight both great potential for and threats to improving health by 2030. To fully deliver ... -
Rapid Determination Of Rifampin Resistance In Clinical Isolates Of Mycobacterium Tuberculosis By Real-Time Pcr
(Amer Soc Microbiology, 2005)Real-time PCR was used to determine rifampin resistance in clinical isolates of Mycobacterium tuberculosis. Ninety-six rifampin-resistant isolates and 23 rifampin-susceptible isolates were included in the study. A 305-bp ... -
Unsupervised Segmentation And Classification Of Cervical Cell Images
(Elsevier Sci Ltd, 2012)The Pap smear test is a manual screening procedure that is used to detect precancerous changes in cervical cells based on color and shape properties of their nuclei and cytoplasms. Automating this procedure is still an ... -
FAKTÖR ANALİZİNDE BELİRLİ KOŞULLAR ALTINDA FAKTÖR SAYISI BELİRLEME YÖNTEMLERİNİN KARŞILAŞTIRILMASI
(Sağlık Bilimleri Enstitüsü, 2020-02-14)Factor analysis is one of the multivariate statistical techniques used in the field of health, sport, education, and social sciences about especially scale development studies. In this technique, determining of retained ... -
Validation of the Eortc Qlq-Oes18 Questionnaire in Patients Treated with Radiotherapy
(Akad Doktorlar Yayınevi, 2017)Esophagitis is a very common toxicity of radiotherapy (RT). European Organization for the Research and Treatment of Cancer (EORTC) quality of life questionnaire (QLQ)-OES18 can be used to measure the quality of life (QoL) ... -
Central Nervous System Infections In The Absence Of Cerebrospinal Fluid Pleocytosis
(Elsevier Science Bv, 2017)Previous multicenter/multinational studies were evaluated to determine the frequency of the absence of cerebrospinal fluid pleocytosis in patients with central nervous system infections, as well as the clinical impact of ... -
BİLİNEN METABOLİK HASTALIKLAR VE SENDROMLAR İLE İLİŞKİLENDİRİLEMEYEN KONJENİTAL/GELİŞİMSEL KATARAKTLARDA YENİ NESİL DİZİLEME İLE MOLEKÜLER ETİYOLOJİNİN ARAŞTIRILMASI
(Sağlık Bilimleri Enstitüsü, 2020)The aim of the study was to identify the molecular etiology in patients with congenital/developmental cataract which can not be attributed to known metabolic diseases or syndromes by next generation sequencing. A total of ... -
Typing Of Urinary Jc Virus Dna Offers A Novel Means Of Tracing Human Migrations
(Natl Acad Sciences, 1997)Although polyomavirus JC (JCV) is the proven pathogen of progressive multifocal leukoencephalopathy, the fatal demyelinating disease, this virus is ubiquitous as a usually harmless symbiote among human beings. JCV propagates ... -
Unusual Extramedullary Recurrence And Renal Relapse Despite Complete Chimerysm After Allografting In Ph+ All
(Akad Doktorlar Yayınevi, 2012)Extramedullary recurrences with or without bone marrow involvement are reported in up to a half of leukemic relapses after bone marrow transplantation. Extramedullary relapse of acute lymphoblastic leukemia (ALL) in the ... -
Upper Extremity Function In Elderly Patients With Breast Cancer-Related Lymphedema: A Descriptive Study
(Gunes Kitabevi Ltd Sti, 2018)Introduction: Lymphedema is a common complication following breast cancer treatment with physical and pyschosocial consequences. The detrimental effects of lymphedema may become more disabiling in conjuction with the aging ... -
Uzamış Öksürüğü Olan Erişkinlerde Bordetella pertussis Enfeksiyonunun Serolojik Olarak Değerlendirilmesi
(Ankara Microbiology Soc, 2016)Aşı ile önlenebilen bir hastalık olan boğmaca, enfekte bireylerden duyarlı kişilere solunum yolu ile bulaşmaktadır. Bordetella pertussis enfeksiyonuna karşı, aşı veya doğal enfeksiyon sonucu gelişen immün yanıt ömür boyu ... -
Results From The Survey Of Antibiotic Resistance (Soar) 2002-09 In Turkey
(Oxford Univ Press, 2016)Objectives: To investigate changes in antibiotic susceptibility of Streptococcus pneumoniae and Haemophilus influenzae from the Survey of Antibiotic Resistance (SOAR) in community-acquired respiratory tract infections ... -
Riboflavin-Responsive And -Non-Responsive Mutations In Fad Synthase Cause Multiple Acyl-Coa Dehydrogenase And Combined Respiratory-Chain Deficiency
(Cell Press, 2016)Multiple acyl-CoA dehydrogenase deficiencies (MADDs) are a heterogeneous group of metabolic disorders with combined respiratory-chain deficiency and a neuromuscular phenotype. Despite recent advances in understanding the ... -
Risk Factors For Breast Cancer In Turkish Women With Early Pregnancies And Long-Lasting Lactation - A Case-Control Study
(Taylor & Francis As, 2002)A hospital-based case-control study was carried out among 504 women with breast cancer and 610 controls to analyse the risk factors for breast cancer in Turkey. Adjusted odds ratios (ORs) and 95% confidence intervals (CIs) ... -
Results From The Survey Of Antibiotic Resistance (Soar) 2011-13 In Turkey
(Oxford Univ Press, 2016)Objectives: Data are presented from the Survey of Antibiotic Resistance (SOAR) for respiratory tract infection pathogens collected in 2011-13 from Turkey. Methods: MICs were determined using Etest (R). Susceptibilitywas ... -
Reversible Expression Of Flagella In Campylobacter Spp.
(Oxford Academic, 1992)The in vitro phase variation of flagella and the transition rates between flagellate and aflagellate phenotypes in Campylobacter species including C. jejuni, C. coli, C. lari (thermophilic campylobacters), C. fetus subsp. ... -
Primer Hiperparatiroidizm Cerrahisinde Preoperatif Lokalizasyon
(Ortadogu Ad Pres & Publ Co, 2011)Objective: Primary hyperparathyroidism is the disturbance of calcium metabolism as the result of excessive parathormone secretion. The most common cause is parathyroid adenoma. The need for localization methods and preference ... -
Sandfly Fever Virus Activity In Central/Northern Anatolia, Turkey: First Report Of Toscana Virus Infections
(Wiley-Blackwell, 2011)Sandfly fever viruses (SFVs) cause febrile diseases as well as aseptic meningitis/encephalitis and include serotypes sandfly fever Sicilian virus (SFSV), sandfly fever Naples virus (SFNV) and Toscana virus (TOSV). Infections ...
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