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dc.contributor.authorOzdogan, Selcuk
dc.contributor.authorNurhat, Raziye Handan
dc.contributor.authorDuzkalir, Ali Haluk
dc.contributor.authorYuce, Deniz
dc.contributor.authorSabuncuoglu, Hakan
dc.contributor.authorGokcil, Zeki
dc.contributor.authorErdogan, Ersin
dc.date.accessioned2019-12-12T06:48:29Z
dc.date.available2019-12-12T06:48:29Z
dc.date.issued2016
dc.identifier.issn1019-5149
dc.identifier.urihttps://doi.org/10.5137/1019-5149.JTN.8534-13.2
dc.identifier.urihttp://hdl.handle.net/11655/17094
dc.description.abstractAIM: The aim of this study was to find out if vagal nerve stimulation (VNS) affect the generalized-partial seizure count and medical treatment in adult drug resistant epilepsy patients. MATERIAL and METHODS: Twenty adult patients who were diagnosed with drug-resistant epilepsy were investigated retrospectively for vagal nerve stimulator implantation between 2001 and 2010 at the Neurosurgery Departments of Ufuk University and Gulhane Military Medical Academy. The effects of vagal nerve stimulation on generalized-partial seizures and medical treatment was scored and if a significant difference was found, a comparison was made by Wilcoxon Signed Ranks test and Pairwise. For all the group analyses, the statistical significant rank was accepted as a p value <0.05. Bonferroni correction was made when it was needed during pairwise comparisons. RESULTS: VNS significantly decreased the scores of generalized-partial seizures. There was no decrease in the doses of anti epileptic drugs and the medical treatment was resumed as before the implantation. The results were correlated with the relevant literature. CONCLUSION: VNS is an alternative treatment option for drug resistant epilepsy for patients who are not ideal candidates for surgery or are not healed after epilepsy surgery.
dc.language.isoen
dc.publisherTurkish Neurosurgical Soc
dc.relation.isversionof10.5137/1019-5149.JTN.8534-13.2
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectNeurosciences & Neurology
dc.subjectSurgery
dc.titleVagal Nerve Stimulation Effects On Generalized-Partial Seizures And Medication In Adult Drug-Resistant Epilepsy Patients
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.relation.journalTurkish Neurosurgery
dc.contributor.departmentBeyin ve Sinir Cerrahisi
dc.identifier.volume26
dc.identifier.issue3
dc.identifier.startpage347
dc.identifier.endpage351
dc.indexingWoS
dc.indexingScopus


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