Antibacterial Chitosan/Silk Sericin 3D Porous Scaffolds As A Wound Dressing Material
Denkbas, Emir Baki
Üst veriTüm öğe kaydını göster
Antimicrobial mixed dressings have traditionally been used to minimize bacterial infection of burns and other wounds. This study presents the advancement of biocompatible chitosan/silk sericin (CHT/SS) scaffolds combined with lauric acid (LA) and zinc oxide nanoparticles (nZnO) for the successful wound dressing applications. Antibacterial assay results showed that the diameters of the inhibition zone increased from 2 +/- 0.4 to 7 +/- 0.1mm for Escherichia coli, as well as from 2.5 +/- 0.2 to 6 +/- 0.4mm for Staphylococcus aureus while CHTS/SS/100nZnO compared to CHT/SS/0.01LA. The results not only showed excellent inhibition against Gram-positive and Gram-negative bacterial growth but also revealed improved proliferation and extended viability for HaCaT cells.