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dc.contributor.advisorDemiryürek, M.Deniz
dc.contributor.advisorSürücü, H.Selçuk
dc.contributor.authorİsmayılov, Turab
dc.date.accessioned2020-01-17T07:01:02Z
dc.date.issued2020
dc.date.submitted2019-12-06
dc.identifier.citation1. Bechara FG, Georgas D, Sand M, Stücker M, Othlinghaus N, Altmeyer P, Gambichler T: Effects of a long-pulsed 800-nm diode laser on axillary hyperhidrosis: a randomized controlled half-side comparison study, Dermatol Surg. 2012 May;38(5):736-40. 2. Gray H, Williams P.L, Bannister L.H. Gray's Anatomy: The Anatomical Basis of Clinical Practice, 40 ed. United States of America: Churchill Livingstone. Bölüm: 50, 2008. 3. Aydin F, Pancar GS, Senturk N, Bek Y, Yuksel EP, Canturk T, Turanli AY:Axillary hair removal with 1064nm Nd:YAG laser increases sweat production, Clin Exp Dermatol. 2010 Aug;35(6):588-92. 4. Beer GM, Baumuller S, Zech N, Wyss P, Strasser D, Varga Z, Seifert B, Hafner J, Mihic-Probst D: Immunohistochemical differentiation and localization analysis of sweat glands in the adult human axilla, Plast Reconstr Surg. 2006;117(6): 2043–2049. 5. Laubach HJ, Makin IR, Barthe PG, Slayton MH, Manstein D:Intense focused ultrasound: evaluation of a new treatment modality for precise microcoagulation within the skin, Dermatol Surg. 2008 May;34(5):727-34. 6. White WM, Makin IR, Barthe PG, Slayton MH, Gliklich RE:Selective creation of thermal injury zones in the superficial musculoaponeurotic system using intense ultrasound therapy: a new target for noninvasive facial rejuvenation, Arch Facial Plast Surg. 2007 Jan-Feb;9(1):22-9. 7. Gliklich RE, White WM, Slayton MH, Barthe PG, Makin IR:Clinical pilot study of intense ultrasound therapy to deep dermal facial skin and subcutaneous tissues, Arch Facial Plast Surg. 2007 Mar-Apr;9(2):88-95. 8. Strutton DR, Kowalski JW, Glaser DA, Stang PE: Us prevalence of hyperhidrosis and impact on individuals with axillary hyperhidrosis: Results from a national survey, J Am Acad Dermatol. 2004;51(2):241–248. 9. Johnson JE, O'Shaughnessy KF, Kim S: Microwave thermolysis of sweat glands, Lasers Surg Med. 2012 Jan;44(1):20-5 10. Leclère FM, Moreno-Moraga J, Alcolea JM, Vogt PM, Royo J, Cornejo P, Casoli V, Mordon S, Trelles MA: Efficacy and safety of laser therapy on axillary hyperhidrosis after one year follow-up: a randomized blinded controlled trial, Lasers Surg Med. 2015 Feb;47(2):173-9 11. Serge R. Mordon, Mario A Trelles, Franck Marie Leclère, Nacim B: New treatment techniques for axillary hyperhidrosis, J Cosmet Laser Ther. 2014 Oct;16(5):230-5 12. A New Technique Kota Ichikawa, M.D.Muneo Miyasaka, M.D.Yoshiyuki Aikawa: Subcutaneous Laser Treatment of AxillaryOsmidrosis, Plast Reconstr Surg. 2006 Jul;118(1):170-4 13. Park, Y. J., and Shin, M. S.: What is the best method for treating osmidrosis? Ann. Plast. Surg. 47: 303, 2001. 14. Kim, I. H., Seo, S. L., and Oh, C. H.: Minimally invasive surgery for axillary osmidrosis: Combined operation with CO2 laser and subcutaneous tissue remover, Dermatol. Surg. 25: 875, 1999. 15. LakrajAA, MoghimiN, JabbariB:Hyperhidrosis: anatomy, pathophysiology and treatment with emphasis on the role of botulinum toxins, Toxins (Basel). 2013 Apr 23;5(4):821-40 16. Davarian S., Kalantari K.K., Rezasoltani A., Rahimi A.:Effect and persistency of botulinum toxin iontophoresis in the treatment of palmar hyperhidrosis, Australas. J. Dermatol. 2008;49:75–79. doi: 10.1111/j.1440-0960.2008.00441.x. 17. Montaser-Kouhsari L., Zartab H., Fanian F., Noorian N., Sadr B., Nassiri-Kashani M., Firooz A.: Comparison of intradermal injection with iontophoresis of abobotulinum toxin a for the treatment of primary axillary hyperhidrosis: A randomized, controlled trial, J. Dermatolog. Treat. 2013 18. Kavanagh G.M., Shams K.: Botulinum toxin type a by iontophoresis for primary palmar hyperhidrosis, J. Am. Acad. Dermatol. 2006;55:S115–S117. doi: 10.1016/j.jaad.2005.07.017. 19. Leung A.K.C., Chan P.Y.H., Choi M.C.K.: Hyperhidrosis, Int. J. Dermatol. 1999;38:561–567. 20. Stolman L.P. Hyperhidrosis: Medical and surgical treatment, Eplasty. 2008;8:e22. 21. Del Sorbo F., Brancati F., de Joanna G., Valente E.M., Lauria G., Albanese A.: Primary focal hyperhidrosis in a new family not linked to known loci, Dermatology. 2011;223:335–342. 22. RomeroFR, HaddadGR, MiotHA, CataneoDC:Palmar hyperhidrosis: clinical, pathophysiological, diagnostic and therapeutic aspects, An Bras Dermatol. 2016 Nov-Dec;91(6):716-725tr_TR
dc.identifier.urihttp://hdl.handle.net/11655/21728
dc.description.abstractİsmayilov.T. Microscopic Evaluation of The Treatment of Sweating Therapies In Experimental Animal Model. Hacettepe University, Graduate School of Health Sciences, Ph.D. Thesis in Anatomy, Ankara, 2019. In this study, in experimental animal model LASER and ultrasonic energy source was compared. Comparison of LASER in different wave and energy dimensions was also performed. All the results were analyzed with electron microscopy. Because of the high tissue damage in the examination results, we included the plastic reconstructive surgeon's frequently used high focus ultrasonography device (ultrasonic sound wave ablation) in our experiment. In this study, three different skin layer efficient high focus ultrasonography device were used. Control biopsies were taken after the application of each experimental animal to the hands and feet. These biopsies were histologically examined. As a result of the study, the number of sweat glands decreased significantly in the microscopically used 3 and 4.5 mm high focus ultrasonography headings, and the total accumulation of lymphocyte infiltration and fibroblast in the deep dermis layer was also observed in the 4.5 mm title. As a result, in the microscopic examination of samples taken after applications of 3.0 mm and 4.5 mm titles in this experiment, we can say that the headings used are more targeted and less tissue damage.tr_TR
dc.language.isoturtr_TR
dc.publisherTıp Fakültesitr_TR
dc.rightsinfo:eu-repo/semantics/openAccesstr_TR
dc.rights.urihttp://creativecommons.org/publicdomain/zero/1.0/*
dc.subjectLASER, ultrasonik enerji, terleme tedavisi, fokuslu ultrason, hiperhidrozistr_TR
dc.titleDENEYSEL HAYVAN MODELİNDE EKSTEMİTELERDE TERLEME TEDAVİLERİNİN MİKROSKOBİK OLARAK DEĞERLENDİRİLMESİtr_TR
dc.typeinfo:eu-repo/semantics/doctoralThesistr_TR
dc.description.ozetİsmayılov, T. Deneysel Hayvan Modelinde Terleme Tedavilerinin Mikroskopik Olarak Değerlendirilmesi. Hacettepe Üniversitesi Sağlık Bilimleri Enstitüsü Anatomi Programı Doktora Tezi, Ankara, 2019. Bu çalışmada, deneysel hayvan modelinde LASER ve ultrasonik enerji kaynağı ile karşılaştırılmalı olarak uygulandı. LASER’in farklı dalga ve enerji boyutunda karşılaştırılması yapıldı. Bütün sonuçlar elektron mikroskopla incelendi. İnceleme sonuçlarında oluşan yüksek doku hasarı nedeniyle, deneyimize plastik rekonstruktif cerrahin sık kullanılan fokuslu ultrasonografi cihazını (ultrasonik ses dalgası ile ablasyon) dahil ettik. Çalışmada cihazının farklı deri katmanlarında etkili olan 3 başlığı kullanıldı. Her deney hayvanında el ve ayak bölgelerine uygulamalardan sonra kontrol biopsiler alındı. Bu biopsiler histolojik olarak incelendi. İnceleme sonucunda 3,0 mm ve 4,5 mm lik fokuslu ultrasonografi başlıkları kullanılan mikroskobik incelemede ter bezlerinin sayısının ciddi şekilde azaldığı ve ayrıca 4,5 mm lik başlık kullanılan incelemede derin dermis tabakasında lenfosit infiltrasyonu ve fibroblast birikimi saptandı. Sonuç olarak bu deneyde 3,0 mm ve 4,5 mm başlık kullanılan uygulamalar sonrası alınan örneklerin mikroskopik incelemelerinde, kullanılan başlıkların daha hedefe yönelik olduğu ve daha az doku hasarı oluşturduğunu söyleyebiliriz.tr_TR
dc.contributor.departmentAnatomitr_TR
dc.embargo.termsAcik erisimtr_TR
dc.embargo.lift2020-01-17T07:01:02Z
dc.fundingYoktr_TR


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