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dc.contributor.authorÖzdemir, H.
dc.contributor.authorDevelioǧlu, H.
dc.contributor.authorYamalik, N.
dc.contributor.authorAydin, H.
dc.contributor.authorEren, K.
dc.date.accessioned2020-01-21T07:21:26Z
dc.date.available2020-01-21T07:21:26Z
dc.date.issued2014
dc.identifier.issn1302-5805
dc.identifier.urihttps://doi.org/10.7126/cdj.58140.5000004490
dc.identifier.urihttps://www.scopus.com/inward/record.url?eid=2-s2.0-84905985885&partnerID=40&md5=c29dd199daa5e4aaf7f79346646386e0
dc.identifier.urihttp://hdl.handle.net/11655/21852
dc.description.abstractObjectives: To evaluate the effect of periodontal therapy on clinical parameters as well as on myeloperoxidase (MPO) activity in the gingival crevicular fluid (GCF) of patients with type 2 diabetes mellitus and of systemically healthy individuals. Materials and Methods: 24 type 2 DM patients subjects, and 21 systemically healthy individuals, both groups with chronic periodontitis, and systemically and periodontally healthy individuals were enrolled. Periodontal clinical parameters, namely periodontal probing depth (PD), plaque index (PI), gingival index (GI), clinical attachment level (CAL), and gingival bleeding time index (GBI), as well as GCF MPO activity, were assessed before and 3 months after non-surgical periodontal therapy. GCF enzyme activity was spectrophotometrically analyzed. Possible correlation between clinical periodontal status and MPO activity was also evaluated. Results: Despite the relatively stable clinical measures and GCF MPO content in the periodontally-healthy subjects, the clinical periodontal status improved, as significant reductions were observed in all of the clinical parameters in periodontitis patients with and without diabetes (p<0.05). GCF MPO activity presented with significant reductions in both of the periodontally-diseased groups after phase I treatment (p<0.05), however it could not reach to the level of periodontal health (p<0.05). Conclusions: Periodontal inflammation is likely to play the major role in the higher MPO activity observed at diseased sites, while diabetes mellitus do not seem to further increase the production of this enzyme. Periodontal treatment can provide successful improvement in clinical periodontal parameters and reduction in enzyme profile of GCF in diabetics.tr_TR
dc.language.isoentr_TR
dc.publisherCumhuriyet Universitytr_TR
dc.relation.isversionof10.7126/cdj.58140.5000004490tr_TR
dc.rightsinfo:eu-repo/semantics/openAccesstr_TR
dc.subjectMyeloperoxidasetr_TR
dc.subjectDiabetes mellitustr_TR
dc.subjectCronic periodontitistr_TR
dc.subjectGingival crevicular fluidtr_TR
dc.subject.lcshPeriodontolojitr_TR
dc.titleComparative Analysis of The Potential Effect of Phase I Therapy on Gingival Crevicular Fluid Myeloperoxidase Levels In Non-Diabetic And Diabetic Patients With Periodontitistr_TR
dc.typeinfo:eu-repo/semantics/articletr_TR
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.relation.journalCumhuriyet Dental Journaltr_TR
dc.contributor.departmentPeriodontolojitr_TR
dc.identifier.volume17tr_TR
dc.identifier.issue3tr_TR
dc.identifier.startpage256tr_TR
dc.identifier.endpage266tr_TR
dc.indexingScopustr_TR
dc.fundingYoktr_TR


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