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dc.contributor.authorSonmezler, Merve
dc.contributor.authorOzgur, Erdogan
dc.contributor.authorYavuz, Handan
dc.contributor.authorDenizli, Adil
dc.date.accessioned2021-06-09T06:47:08Z
dc.date.available2021-06-09T06:47:08Z
dc.date.issued2019
dc.identifier.issn2169-1401
dc.identifier.urihttp://dx.doi.org/10.1080/21691401.2018.1548474
dc.identifier.urihttp://hdl.handle.net/11655/24856
dc.description.abstractHerein, quartz crystal microbalance (QCM) biosensor is prepared for the detection of L-histidine by attachment of L-histidine imprinted poly(EGDMA-MAH/Cu(II)) nanoparticles on QCM electrode. The imprinted nanoparticles with the size of 86.43 nm were synthesized via miniemulsion polymerization reaction. Prepared QCM sensors were characterized with ellipsometer, contact angle measurements and FTIR. The thickness measurements demonstrated that the particle thin films were almost mono-layer. L-histidine solutions with a concentration range between 6.44 mu M and 225.6 mu M were introduced to QCM system to determine the adsorption kinetics. Selectivity of the L-histidine imprinted nanoparticles were examined using D-histidine and L-tryptophan as competitor molecules. L-histidine imprinted QCM biosensors was also used for RNAase, lysozyme, cytochrome-C and BSA to investigate the competitive adsorption of surface histidine exposed proteins.
dc.language.isoen
dc.relation.isversionof10.1080/21691401.2018.1548474
dc.rightsAttribution 4.0 United States
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectmolecular imprinting
dc.subjectquartz crystal microbalance
dc.subjectamino acid detection
dc.subjectL-histidine
dc.titleQuartz Crystal Microbalance Based Histidine Sensor
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.relation.journalArtificial Cells Nanomedicine And Biotechnology
dc.contributor.departmentKimya
dc.identifier.volume47
dc.identifier.issue1
dc.description.indexWoS
dc.description.indexScopus


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Attribution 4.0 United States
Except where otherwise noted, this item's license is described as Attribution 4.0 United States