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Kanser Hastalarında Tromboz Riskinin ve Antikoagülan Tedavinin Rehbere Uygunluğunun Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2020-01-15)Cancer patients are at high risk for venous thromboembolism (VTE) and cancer-associated VTE is a major health problem due to its effects on deterioration of disease prognosis, increased treatment costs and delayed cancer ... -
Kanser Hastalarının Opioid Analjezik Kullanımına İlişkin Görüşlerinin Değerlendirilmesi ve Hasta Eğitiminde Klinik Eczacının Rolü
(Sağlık Bilimleri Enstitüsü, 2020)Pain is a common syndrome among cancer patients that has a negative impact on the physiological functions, psychological well-being, quality of life of patients, and that also requires a good management. Patients and their ... -
Farelerde lipopolisakkarit ile indüklenen solunum yolu inflamasyonunda mitokondriye hedeflendirilmiş yavaş hidrojen sülfür salıveren AP39'un ve nitrik oksit sentaz inhibitörü asimetrik dimetil arjinin (ADMA)'nın etkilerinin araştırılması
(Sağlık Bilimleri Enstitüsü, 2019)In this study, the effects of mitochondria-targeted slow H2S releasing donor AP39 on lipopolysaccharide (LPS)-induced airway inflammation were investigated in in vitro and in vivo models. In in vitro model tracheal rings ... -
Nandrolonun Genotoksisitesinin Tek Hücre Jel Elektroforez Tekniği İle İn Vitro İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2019)Nandrolone decanoate is among the most widely used anabolic androgenic steroids (AAS) that are often abused by young people and athletes to improve muscle strength and performance. It is a subjected to control in many ... -
TOTAL PARENTERAL BESLENME (TPN) ÇÖZELTİLERİNİ HAZIRLAMAK İÇİN KULLANILAN BİLEŞENLERDE VE TPN ÇÖZELTİLERİNDE OLASI ALÜMİNYUM KONTAMİNASYONUNUN ARAŞTIRILMASI
(Sağlık Bilimleri Enstitüsü, 2019)Inorganic toxicity awareness and research has been increasingly echoed in the scientific world with increasing exposure to metals. Aluminum (Al), which is one of the most known metals, has attracted attention with its ... -
SIKLIKLA KULLANILAN BİTKİSEL ÜRÜNLERİN İLAÇLAR İLE OLASI ETKİLEŞMELERİNİN ECZACILAR TARAFINDAN FARKINDALIKLARININ DEĞERLENDİRİLMESİ
(Sağlık Bilimleri Enstitüsü, 2019-09-19)The use of herbal medicines and nutritional supplements has been increased dramatically in many parts of the world. Since many herbal products has been sold over the internet. It is difficult to evaluate the extent of the ... -
İnsan Mide Adenokarsinoma Hücrelerinde Helicobacter Pylori'nin Neden Olduğu DNA Çift Sarmal Kırıkları ve Oksidatif Stresin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2019-09-27)Didem, O. Evaluation of DNA Double-Strand Breaks and Oxidative Stress caused by Helicobacter pylori in Human Adenogastric Carcinoma Cells. Hacettepe University Graduate School of Health Sciences, Pharmaceutical Toxicology ... -
Kondanse 1,4-Dihidropiridin Türevlerinin Sentezi ile Antimikrobiyal ve Antioksidan Etkileri Üzerinde Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2019)BAYDAR, E. The Studies on Synthesis of Condensed 1,4-Dihydropyridine Derivatives and Their Antimicrobial and Antioxidant activities, Hacettepe University, Graduate School of Health Sciences, Master Thesis in Pharmaceutical ... -
Kondanse 1,4-Dihidropiridin Türevlerinin Sentezi ve L-/T-Tipi Kalsiyum Kanalları Üzerine Etkileri
(Sağlık Bilimleri Enstitüsü, 2019)1,4-Dihydropyridines (DHPs) are crucial blockers of different calcium channel subtypes and have great therapeutic value against cardiovascular and neurophysiologic conditions. In this thesis, the design and the synthesis ... -
Demans Hastalarında Tedaviye Uyunç Ve Klinik Eczacının Rolü
(Sağlık Bilimleri Enstitüsü, 2019)Due to the increase in the elderly population in the world and in our country, the prevalence of dementia, which is one of the most common diseases in this age group, is rapidly increasing. Early diagnosis and treatment ... -
İnme Geçiren Hastalarda Yaşam Kalitesi ve Tedaviye Uyunç Üzerine Klinik Eczacının Katkısı
(Sağlık Bilimleri Enstitüsü, 2019)Stroke is defined as the sudden onset of a focal neurological problem lasting more than 24 hours, is one of the leading causes of repetitive and disability, affecting the quality of life of the patients negatively, causing ... -
Kojik Asit Türevi Bileşiklerin Tasarımı, Sentezi ve Melanoma Hücresine Karşı Sitotoksisiteleri ile Tirozinaz İnhibisyonu Etkilerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2019)Tyrosinase is an enzyme that acts as a catalyst in the biosynthesis of melanin pigment, which is found in fungi, in plants and in animals. Overproduction and accumulation of this pigment causes hyperpigmentation, post ... -
Bazı 2-Sübstitüe-1H-Benzimidazol Türevleri Üzerinde Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2019)In this study, 12 (1 of registered in the literature) 2-(1H-benzo[d]imidazol-2-yl)-3-(4-(4-substitutedpiperazin-1- yl)phenyl)acrylonitrile (3a-l) and 3 2-(1H-benzo[d]imidazol-2-yl)-3-(4-(4- substitutedpiperazin-1-yl)p ... -
Afyonkarahisar İli Jeotermal Su Kaynaklarından İzole Edilen Mikroalgal Türler Üzerinde Farmakognozik Araştırmalar
(Sağlık Bilimleri Enstitüsü, 2019)Sensoy, M., Pharmacognosic Researches on Isolated Microalgal Species from Geothermal Springs of Afyonkarahisar Province, Hacettepe University, Graduate School of Health Sciences, Pharmacognosy Programme Master of Science ... -
Tiroid Hücrelerinde Bisfenol A’nın Toksik Etkileri ve Selenyum Bileşiklerinin Koruyucu Rolünün Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2019)Bisphenol A (BPA) is a chemical compound that is used in the production of polycarbonates and epoxy resins. Humans are widely exposed to this compound by oral, inhalation and dermal routes in daily life. It is known to ... -
Türkiye'de Yetişen Bazı Acanthus L. Türlerinden İlaç Adayı Bileşiklerin İzolasyonu
(Sağlık Bilimleri Enstitüsü, 2019)Sarikaya Aydin, S., Isolation of Drug Candidate Compounds from Some Acanthus L. Species Growing in Turkey, Hacettepe University, Graduate School of Health Sciences, Pharmacognosy Program, Doctor of Philosophy Thesis, ... -
İnsan Nöroblastoma Hücre Kültüründe Amiloid Beta ile Oluşturulan Alzheimer Hastalığı Modelinde Atorvastatinin Sestrin-2, Sirtuin-1, TPP1 ve LC3B Ekspresyonuna Etkisi.
(Sağlık Bilimleri Enstitüsü, 2019-02)Çelik, H. The Effect of Atorvastatin on Sestrin-2, Sirtuin-1, TPP1 and LC3B in Amyloid Beta Induced Alzheimer’s Disease Model in Human Neuroblastoma Cell Culture. Hacettepe University Graduate School of Health Sciences, ... -
Yağ Asidi Amid Hidrolaz (Faah) ve Monoaçil Gliserol Lipaz (Magl) İnhibitörlerinin Farede Deneysel Solunum Yolu İnflamasyonu Üzerindeki Etkileri
(Sağlık Bilimleri Enstitüsü, 2019-01-15)The endocannabinoid system is a modulator of physiological functions in various biological systems including the airways. In the present study the effects of treatment with the inhibitors of endocannabinoid-degrading enzymes ... -
Flurbiprofenin Sitotoksik, Genotoksik ve Apoptotik Etkilerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2018-11-02)B Bakir, E., Evaluation of Cytotoxic, Genotoxic and Apoptotic Effect of Flurbiprofen, Hacettepe Un¬vers¬ity Graduate School Health Sciences Pharmacy Department of Pharmaceutical Toxicology Doctor of Phi¬losophy Thes¬is, ... -
Türkiye'de Faaliyet Gösteren İlaç Firmalarının Web Siteleri Üzerine Bir Araştırma
(Sağlık Bilimleri Enstitüsü, 2018-10-17)Kayıran, B., A Study on Web Sites of Drug Companies in Turkey, Hacettepe University Graduate School of Health Sciences Master Thesis in Pharmacy Management and Legislation. Ankara, 2018. The Internet, which has been in use ...
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