Browsing Eczacılık Meslek Bilimleri Bölümü Tez Koleksiyonu by Title
Now showing items 60-79 of 94
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Obez Çocuklarda Tiroid Işlev Bozuklukları ve Oksidan Antioksidan Statü Arasındaki Ilişkinin Metabolik Risk Etmenleri ile Birlikte Değerlendirilmesi.
(Sağlık Bilimleri Enstitüsü, 2013)Obesity has been defined as “abnormal or excessive fat accumulation that may impair health” by World Health Organization. Obesity is a chronic illness the prevalence of which has increased in both developed and developing ... -
Perflorooktanoik Asitin Sitotoksisite Ve Oksidatif Stres Indükleyici Etkilerinin In Vivo Ve In Vitro Sistemlerde Araştırılması
(Sağlık Bilimleri Enstitüsü, 2015)Perfluorooctanoic acid (PFOA) is a persistent environmental pollutant of toxicological importance. However, its mechanism of toxicity was not well-characterized. The aim of this study was to investigate the possible ... -
Pharmacognostıcal Investıgatıons Oprunus Mahaleb Oıl and Its Kernels
(Sağlık Bilimleri Enstitüsü, 2014)Medicinal plants are getting worthy all over the world due to their therapeutic usage. Among medicinal plants in Turkey, Prunus mahaleb L. ( syn. Cerasus mahaleb L. Mill.) is commonly known as mahlep, mehlep, idris agac, ... -
Phytochemıcal and Pharmacologıcal Studıes on Some Papaver Specıes in Turkey
(Sağlık Bilimleri Enstitüsü, 2017-08-14)Papaver species have been used for treating varieties of diseases including depression for centuries in Anatolia. We screened five Papaver species plant extracts for their antidepressant-like activity in vivo and their ... -
Piknogenol ve Kurkuminin Çeşitli Kanser Hücre Hatlarında Sisplatin Sitotoksisitesine Etkilerinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2017-01-13)Pycnogenol from Pinus pinaster and curcumin from Curcuma longa L., are poliphenolic compounds and commonly used in many diseases traditionally due to their high antioxidant properties. Cisplatin, an antineoplastic agent, ... -
Pitavastatin Sitotoksisitesinin Serviks Kanser Hücre (Hela) Hattında Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2018)Cervical cancer which is one of the most common cancer types in women throughout the world. Investigation of possible and alternative treatment methods of cervical cancer will lead to the discovery of new effective treatment ... -
Plantago holosteum Scop. Üzerinde Farmakognozik Araştırmalar
(Sağlık Bilimleri Enstitüsü, 2017)ABSTRACT Genç, Y., Pharmacognostical Investigations on Plantago holosteum Scop., Hacettepe University, Institute of Health Sciences, Pharmacognosy Program, Doctor of Philosophy Thesis, Ankara, 2017. The genus Plantago ... -
Potentilla speciosa Willd. var. speciosa Willd. ve sekonder metabolitlerinin α-glukozidaz ve tirosinaz inhibitör etkilerinin araştırılması
(Sağlık Bilimleri Enstitüsü, 2021)Özgünseven, A., Investigation of α-glucosidase and tyrosinase inhibitory effects of Potentilla speciosa Willd. var. speciosa Willd. and its secondary metabolites, Hacettepe University, Graduate School Health Sciences, ... -
Prenatal Bisfenol A ve/veya Di-2-Etil Hekzil Ftalat Maruziyetinin Erkek Üreme Sistemi Üzerine Etkilerinin İncelenmesi.
(Sağlık Bilimleri Enstitüsü, 2018-01)Bisphenol A (BPA) and di (2-ethylhexyl) phthalate (DEHP) are chemical substances that are used in a wide variety of industrial products, with proven endocrine disrupting properties. Today, with the increasing use of these ... -
Prenatal Bisfenol A ve/veya Di-2-Etil Hekzil Ftalat Maruziyetinin Nöroendokrin Bozucu Etkilerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2018)Bisphenol A (BPA) and di(2-ethylhexyl) phthalate (DEHP) are chemical substances that are widely present in the environment and known to have endocine disrupting properties. In the recent years, studies have been conducted ... -
Pterjiumda Neopterin Düzeylerinin ve Kinürenin Yolağının Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2018)Kilicarslan B., Evaluation of Neopterin Levels and Kynurenine Pathway in Pterygium, Hacettepe University Institute of Health Sciences Ph.D. Thesis in Pharmaceutical Toxicology, Ankara, 2018. Pterjium is an inflammatory and ... -
Rosa damascena Mill. Farmakope Standartlarının Belirlenmesi, Matriks Metalloproteinaz (MMP) İnhibitör Etkinliklerinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2018-03-08)This thesis is summarized as botanical, phytochemical, analytical and biological activity titles. The morphological and anatomical characteristics of Rosa damascena Mill. (Rosaceae) petals have been described in the botanical ... -
Rumex Crıspus L. Ekstreleri ve Sekonder Metabolitlerinin Mmps İnhibitör Aktiviteleri, Antioksidan Kapasiteleri ve Spf Değerlerinin Araştırılarak, Ciltteki Kollajen Dokuyu Onarıcı Fitokozmetik Ürün Geliştirilmesi
(Sağlık Bilimleri Enstitüsü, 2017)Uzun, M., Development of Collagenous Tissue Restorative Phytocosmetics on Skin by Investigation of MMPs Inhibitory Activities, Antioxidant Capacities and Spf Values of Rumex crispus L. Extracts and Sekonder Metabolites, ... -
Seramik İşçilerinde Mesleki Maruziyete Bağlı Olası Genotoksik Hasarın Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2017)Silicon (Si) is the second most abundant element after oxygen that was mainly found in granite, flint, quartz rocks and stones. Exposure to crystalline silica (SiO2) occurs mainly in foundry, processing of diatomaceous ... -
Silikozis Hastalarında Oksisterol Düzeylerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2018)Silicosis is a chronic inflammatory occupational disease that causes permanent and progressive damage to the lungs resulting from prolonged inhalation of silica (SiO2) particles. A significant number of silicosis cases ... -
Studıes on Some Aryloxymethyl Thıosemıcarbazıde, 1,3,4-Thıadıazole and 1,2,4-Trıazole-5-Thıone Derıvatıves
(Sağlık Bilimleri Enstitüsü, 2013)In this study, twelve 1-(7-methoxy-2-naphthyloxyacetyl)-4-subtituted-3-thiosemicarbazide, 5-(7-methoxy-2-naphthyloxymethyl)-2-substituted amino-1,3,4-thiadiazole and 3-(7-methoxy-2-naphthyloxymethyl)-4-substituted- 1,2 ... -
Synthesıs of Condensed 1,4-Dıhydropyrıdıne Derıvatıves and Evaluatıon of Theır Calcıum Channel Modulatıng and Antıoxıdant Actıvıtıes
(Sağlık Bilimleri Enstitüsü, 2014)In this study, study, a pharmacophore model based on calcium channel blocker ligands was generated by LigandScout and nineteen 2-(methacryloyloxy)ethyl 4-aryl-2,6,6-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate ... -
Sıçan Izole Mezenter Arterinde Kalsiyumsuz Ortamda Elektriksel Alan Uyarısı Ile Elde Edilen Kasılmaların Mekanizmasının Incelenmesi
(Sağlık Bilimleri Enstitüsü, 2014)In the present study, we aimed to examine the effect of blockade of L-type calcium channels (LTCC) and in addition the removal of extracellular calcium, on EFS-induced relaxations in rings of rat mesenteric artery. EFS (30 ... -
Sıçanlarda Adeno İlişkili Viral Vektör Aracılı Gerçekleştirilen Nigral ve Hipokampal Alfasinükleinopati Modelinde Rapamisinin Etkileri
(Sağlık Bilimleri Enstitüsü, 2018)Çınar, E., Effects of Rapamycin In A Rat Model Of Adeno Associated Viral Vector Mediated Nigral and Hippocampal Alpha-synucleinopathy, Hacettepe University Graduate School of Health Sciences, Pharmacology Programme Doctor ... -
Sıklıkla Kullanılan Bitkisel Ürünlerin İlaçlar İle Olası Etkileşmelerinin Eczacılar Tarafından Farkındalıklarının Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2019-09-19)The use of herbal medicines and nutritional supplements has been increased dramatically in many parts of the world. Since many herbal products has been sold over the internet. It is difficult to evaluate the extent of the ...