Browsing Eczacılık Meslek Bilimleri Bölümü Tez Koleksiyonu by Title
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Ankara İlinde Reçetelenen İlaçlara Bağlı İstenmeyen Etkilerin İzlenmesi ve Farmakovijilans Konusunda Farkındalığın Artırılması
(Sağlık Bilimleri Enstitüsü, 2017)Temiz Nemutlu N. Monitoring the Unintended Effects of Prescribed Drugs in Ankara and Improving the Awareness of Pharmacovigilance. Hacettepe University Institute of Health Sciences, Thesis of Master ... -
(Arilalkil)Azol Yapısında Yeni Oksim Ester Türevleri Üzerinde Çalışmalar: Sentez, Biyolojik Aktivite ve Moleküler Modelleme
(Sağlık Bilimleri Enstitüsü, 2018-01-22)In this study, a set of novel oxime esters in (arylalkyl)azole structure were designed based on azole antifungals, especially oxiconazole, and synthesized by the reaction of 1-(4-chlorophenyl)-2-(1H-imidazol/1H-1,2,4-tri ... -
Astragalus Isauricus Hub.-Mor. & Matthews Üzerinde Farmakognozik Araştırmalar
(Sağlık Bilimleri Enstitüsü, 2015)The genus Astaragalus is represented by 445 species 224 of which are endemic in Turkish flora. Astragalus species have been used to obtain “gum tragacanth” for many years. Also, numerous Astragalus species have been used ... -
Bazı 2-(4-Sübstitüe)Fenil-5-Benziliden P-Sübstitüebenziliden-3-Fenilaminotiyazolidin-4-On Türevleri Üzerinde Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2014)In this study, 2 new compunds having 3- (phenylamino)-2-[4-(1H-1,2,4-triazole/imidazolyl)phenyl]-1,3-thiazolidin-4-one (Compounds 1,2) and 9 new compounds having 5-(benzylidene/-psubstitutedbenzylidene)- 3-(phenylamin ... -
Bazı 5-Kloro-2-benzoksazolinon Tiyosemikarbazit, 1,3,4-Tiyadiazol ve 1,2,4-Triazol-5-tiyon Türevleri Üzerinde Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2018)In this study, nineteen new compounds which have 1-[2-(5-chloro-2-benzoxazolinone-3-yl)acetyl]-4-substitutedthiosemicarbazide, 3-[(5-chloro-2-benzoxazolinone-3-yl)methyl]-4-substituted-1H-1,2,4-triazole-5(4H)-thione, ... -
Bazı Benzotiyazol Türevleri Üzerinde Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2018)In this study, fifteen 2-(4-substitutedphenyl)benzo[d]thiazole derivatives carrying substituted piperazine and azole moities at the 4 position of phenyl ring were synthesized, of which two had been reported in literature ... -
Bazı Gentiana Türleri Üzerinde Farmakognozik Araştırmalar
(Sağlık Bilimleri Enstitüsü, 2013)The genus Gentiana (Gentianaceae) consists species with important phytochemical properties and have been widely used in traditional folk medicine. Iridoids, secoiridoids, C-glycosylflavones and xanthones are considered ... -
Bazı N-(4-Sübstitüebenziliden)-5-Fenil-1,3,4-Tiyadiazol-2-Amin Türevleri Üzerinde Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2018)In this study, 9 new compounds having 2-substituted-5-phenyl-1,3,4-thiadiazole structures were synthesized and their antifungal and antibacterial activities were evaluated. Target compounds were synthesized by reaction of ... -
Bazı Yeni 2-Pirazolin Türevlerinin Sentezi ve Monoamin Oksidaz (Mao) İnhibitör Aktiviteleri Üzerinde Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2015)In this study, forty two compounds which have 1-[2-(5-substituted-2- benzoxazolinone-3-yl)acetyl]-3,5-disubstitutedphenyl-4,5-dihydro-1H-pyrazole structure and nine compounds which have N’-(1,3-disubstitutedphenylallyl ... -
Bisfenol Türevlerinin Oksidatif Stres Parametreleri Üzerine Etkilerinin HepG2 Hücrelerinde Karşılaştırmalı Olarak Değerlendirilmesi.
(Sağlık Bilimleri Enstitüsü, 2018)Bisphenols belong to a chemical group known as diphenylmethanes and widely used in the production of polycarbonate plastics, as basic chemicals in the resin coating of food and beverage tins. These substances are suggested ... -
Bitkisel Kaynaklı Fenolik Yapıdaki Bileşiklerin Olası Sitotoksik ve Genotoksik Etkilerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2014)Free oxygen radicals react with genetic material such as DNA, RNA and other cell macromolecules and the cause oxidative damage. There is a worldwide increasing interest about antioxidant compounds which could delay or ... -
Çinko Oksit ve Bakır Oksit Nanoparçacıklarının in Vitro Sistemler Üzerindeki Toksik Etkilerinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2017-09)Zinc oxide (ZnO) and copper oxide (CuO) NPs are commonly used metal nanoparticles with a high toxicity potential. However, information on toxicity mechanisms like other NPs, is limited. In this study, the possible ... -
Deneysel Diyabet Modelinde Hipergliseminin Alzheimer Hastalığı ile İlişkili Proteinler Üzerine Etkisi
(Sağlık Bilimleri Enstitüsü, 2016-12)Diabetes mellitus (DM) which is one of the foremost health problems enhances the risk of Alzheimer’s disease (AD) although the molecular mechanisms behind this association remain unclear. In the present study, selective ... -
Dinitroanilin Herbisitlerin Neden Olduğu Genotoksik Etkilerin ve Epigenetik Değişikliklerin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2015)It has been shown that genetic damage has an improtant role in the mechanisms of cancer and other chronic diseases that have been observed all over the world. Recently, theory about that epigenetic changes are also responsible ... -
Diyabet Hastalarında Pteridinlerin ve İlgili Yolakların Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2018-07-04)Gurcu, S., Evaluation of Pteridins and Related Pathways in Diabetes, Hacettepe University Institute of Health Sciences Ph.D. Thesis in Pharmaceutical Toxicology, Ankara, 2018. Pteridins are heterocyclic compounds that play ... -
Eczane İçi Etkileşimlerin Konuşma Çözümlemesi Yoluyla İncelenmesi: Uzmanlık Bilgisi Gösterimi
(Sağlık Bilimleri Enstitüsü, 2018)Pharmaceutical care is defined as practitioner responsibility that optimizes the patient to use drug treatment as effectively and safely as possible under all circumstances. The importance of communication skills for ... -
Endokrı̇n Bozucu Kı̇myasal Maddelere Kombı̇ne Maruzı̇yetı̇n Etkı̇lerinin Hepg2 Hücre Hattında Değerlendı̇rilmesı̇
(Sağlık Bilimleri Enstitüsü, 2018-04-24)Endocrine disruptors are synthetic or natural substances that disrupt the normal functioning of the body by mimicking or blocking hormones. They are suggested to affect many basic periods and characteristics like growth, ... -
Evaluation Of Cytotoxic and Genotoxic Properties Of Sinapic Acid
(Sağlık Bilimleri Enstitüsü, 2014)Phenolic compounds, one of the most widely occurring groups of phytochemicals, play an important role in the growth and reproduction of plants, providing protection against pathogens and predators, also contributing towards ... -
Evaluation Of Cytotoxicity And Genotoxicity Of Eugenol In Lymphocytes
(Sağlık Bilimleri Enstitüsü, 2014)Eugenol is a volatile phenolic constituent of clove essential oil obtained from Eugenia Caryophyllata buds and leaves. It is a functional ingredient in numerous products. It has been used in the pharmaceutical and cosmetics ...
