In this study, 2 new compunds having 3- (phenylamino)-2-[4-(1H-1,2,4-triazole/imidazolyl)phenyl]-1,3-thiazolidin-4-one (Compounds 1,2) and 9 new compounds having 5-(benzylidene/-psubstitutedbenzylidene)- 3-(phenylamin ...

Essential hypertension has been the first disease to have the highest drug expenditures from the date of constitution of Social Security Institution. In Turkey, Ministry of Health is aiming to treat and control essential ...

In this study, study, a pharmacophore model based on calcium channel blocker ligands was generated by LigandScout and nineteen 2-(methacryloyloxy)ethyl 4-aryl-2,6,6-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate ...

Uveitis is an intraocular inflammation affecting the highly vascularised uveal tissue. Early recognition and appropriate therapeutic intervention of uveitis is important since it may be associated with systemic disease and ...

Silver nanoparticles (Ag-NPs) are widely applied in several products due to their unique physico-chemical properties as well as bactericidal effects. The extensive application of Ag-NPs has raised concerns about their ...

Eugenol is a volatile phenolic constituent of clove essential oil obtained from Eugenia Caryophyllata buds and leaves. It is a functional ingredient in numerous products. It has been used in the pharmaceutical and cosmetics ...

In the present study, we aimed to examine the effect of blockade of L-type calcium channels (LTCC) and in addition the removal of extracellular calcium, on EFS-induced relaxations in rings of rat mesenteric artery. EFS (30 ...

Free oxygen radicals react with genetic material such as DNA, RNA and other cell macromolecules and the cause oxidative damage. There is a worldwide increasing interest about antioxidant compounds which could delay or ...

Nowadays, referrals to emergency departments due to intoxication remains to be important in terms of mortality and morbidity. Among these intoxications, cases with cardiac involvement should be closely monitored. ...

Medicinal plants are getting worthy all over the world due to their therapeutic usage. Among medicinal plants in Turkey, Prunus mahaleb L. ( syn. Cerasus mahaleb L. Mill.) is commonly known as mahlep, mehlep, idris agac, ...