Browsing Temel Eczacılık Bilimleri Bölümü Makale Koleksiyonu by Publisher "Amer Chemical Soc"

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Monoamine Oxidase Inhibitory Activity Of Novel Pyrazoline Analogues: Curcumin Based Design And Synthesis

Badavath, Vishnu Nayak; Baysal, Ipek; Ucar, Gulberk; Sinha, Barij Nayan; Jayaprakash, Venkatesan (Amer Chemical Soc, 2016)

A series of new 2-methoxy-4-(5-pheny1-4,5dihydro-1H-pyrazol-3-yl)phenolderivatives, 4-13, were synthesized and tested for their human MAO inhibitory activity. All the compounds were found to be selective and reversible ...
Monoclonal Antibody That Recognizes Diethoxyphosphotyrosine-Modified Proteins And Peptides Independent Of Surrounding Amino Acids

Onder, Seda; Dafferner, Alicia J.; Schopfer, Lawrence M.; Xiao, Gaoping; Yerramalla, Udaya; Tacal, Ozden; Blake, Thomas A.; Johnson, Rudolph C.; Lockridge, Oksana (Amer Chemical Soc, 2017)

Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are irreversibly inhibited by organophosphorus pesticides through formation of a covalent bond with the active site serine. Proteins that have no active site ...
Use Of Hupresin To Capture Red Blood Cell Acetylcholinesterase For Detection Of Soman Exposure

Onder, Seda; Schopfer, Lawrence M.; Cashman, John R.; Tacal, Ozden; Johnson, Rudolph C.; Blake, Thomas K.; Lockridge, Oksana (Amer Chemical Soc, 2018)

Toxicity from acute exposure to nerve agents and organophosphorus toxicants is due to irreversible inhibition of acetylcholinesterase (AChE) in the nervous system. AChE in red blood cells is a surrogate for AChE in the ...