• Türkçe
    • English
  • English 
    • Türkçe
    • English
  • Login
View Item 
  •   DSpace Home
  • Eczacılık Fakültesi
  • Eczacılık Meslek Bilimleri Bölümü
  • Eczacılık Meslek Bilimleri Bölümü Tez Koleksiyonu
  • View Item
  •   DSpace Home
  • Eczacılık Fakültesi
  • Eczacılık Meslek Bilimleri Bölümü
  • Eczacılık Meslek Bilimleri Bölümü Tez Koleksiyonu
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Tirozin Kinaz İnhibitörleri ile Tedavi Edilen Hastalarda Tedavi İzleminde İlaç Etkileşimleri ve Yan Etkilerin Saptanması ve Önlenmesinde Klinik Eczacının Rolü

Thumbnail
View/Open
Ecz. Kamer TECEN Tez.pdf (2.895Mb)
Date
2016
Author
Kamer, Tecen
xmlui.mirage2.itemSummaryView.MetaData
Show full item record
Abstract
The use of tyrosine kinase inhibitors as targeted therapies in cancer treatment becomes prevalent. The aim of this study was to determine and prevent drug-drug interactions and also to reduce side effects of thyrosine kinase inhibitors in patients by the involvement of clinical pharmacist in therapeutic monitoring. Fifty five patients using tyrosine kinase inhibitors between October 2015 and April 2016 and followed in the Hacettepe University Hospitals Oncology Hospital, Medical Oncology Department were monitored and evaluated by a clinical pharmacist in terms of drug-drug interactions and side effects. During the study, a total of 92 drug interactions were observed, of those 54 (58,69%) were regarded as clinically significant by a clinical pharmacist. Among those clinically significant drug interactions, pharmacist made recommendations about 18 interactions which were accepted by the doctor and required modifications were implemented where necessary. The side effects of therapies were evaluated at the initial and the second visits by clinical pharmacist, and statistically significant differences were found in severity of side effects related with skin, diarrhea, fatigue and thyroid dysfunction (p<0,005). This study showed that the risks related with drug therapies, particularly with drug interactions and side effects can be reduced by the involvement of clinical pharmacist in multidisciplinary health care team in the treatment of cancer patients.
URI
http://hdl.handle.net/11655/2925
xmlui.mirage2.itemSummaryView.Collections
  • Eczacılık Meslek Bilimleri Bölümü Tez Koleksiyonu [94]
Hacettepe Üniversitesi Kütüphaneleri
Açık Erişim Birimi
Beytepe Kütüphanesi | Tel: (90 - 312) 297 6585-117 || Sağlık Bilimleri Kütüphanesi | Tel: (90 - 312) 305 1067
Bizi Takip Edebilirsiniz: Facebook | Twitter | Youtube | Instagram
Web sayfası:www.library.hacettepe.edu.tr | E-posta:openaccess@hacettepe.edu.tr
Sayfanın çıktısını almak için lütfen tıklayınız.
Contact Us | Send Feedback



DSpace software copyright © 2002-2016  DuraSpace
Theme by 
Atmire NV
 

 


DSpace@Hacettepe
huk openaire onayı
by OpenAIRE

About HUAES
Open Access PolicyGuidesSubcriptionsContact

livechat

sherpa/romeo

Browse

All of DSpaceCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsTypeDepartmentPublisherLanguageRightsIndexing SourceFundingxmlui.ArtifactBrowser.Navigation.browse_subtypeThis CollectionBy Issue DateAuthorsTitlesSubjectsTypeDepartmentPublisherLanguageRightsIndexing SourceFundingxmlui.ArtifactBrowser.Navigation.browse_subtype

My Account

LoginRegister

Statistics

View Usage Statistics

DSpace software copyright © 2002-2016  DuraSpace
Theme by 
Atmire NV