Eczacılık Fakültesi
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DİBUTİL FTALATIN İNSAN AKCİĞER HÜCRE HATTINA TOKSİK ETKİLERİNİN DEĞERLENDİRİLMESİ VE ASKORBİK ASİT VE N-ASETİLSİSTEİNİN OLASI KORUYUCU ETKİLERİ
(Sağlık Bilimleri Enstitüsü, 2020)Endocrine disruptings are chemical substances which are generally produced by humans that disrupt the normal functioning of the body by imitating or blocking hormones. The mostly studied phthalate derivative is ... -
Antineoplastik İlaçların DNA ile Etkileşmelerinin UV-Görünür Bölge Spektroskopisi ile İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2020)Atmaca, L., Investigation of Interactions of Antineoplastic Drugs with DNA by UV-Visible Region Spectroscopy, Hacettepe University Graduate School of Health Sciences Department of Analytical Chemistry Master’s Thesis, ... -
Assessment Of Genotoxic Effects Of Pendimethalin In Chinese Hamster Over Cells By The Single Cell Gel Electrophoresis (Comet) Assay
(Turkish Pharmacists Association, 2017)Objectives: Pendimethalin (N-(1-ethylpropyl)-3,4-dimethyl-2,6-dinitrobenzeneamine) is a dinitroaniline herbicide compound which selectively controls weeds. It is a cell division and growth inhibitor. It descends plants in ... -
Kanser Hastalarında Tromboz Riskinin ve Antikoagülan Tedavinin Rehbere Uygunluğunun Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2020-01-15)Cancer patients are at high risk for venous thromboembolism (VTE) and cancer-associated VTE is a major health problem due to its effects on deterioration of disease prognosis, increased treatment costs and delayed cancer ... -
Kanser Hastalarının Opioid Analjezik Kullanımına İlişkin Görüşlerinin Değerlendirilmesi ve Hasta Eğitiminde Klinik Eczacının Rolü
(Sağlık Bilimleri Enstitüsü, 2020)Pain is a common syndrome among cancer patients that has a negative impact on the physiological functions, psychological well-being, quality of life of patients, and that also requires a good management. Patients and their ... -
Farelerde lipopolisakkarit ile indüklenen solunum yolu inflamasyonunda mitokondriye hedeflendirilmiş yavaş hidrojen sülfür salıveren AP39'un ve nitrik oksit sentaz inhibitörü asimetrik dimetil arjinin (ADMA)'nın etkilerinin araştırılması
(Sağlık Bilimleri Enstitüsü, 2019)In this study, the effects of mitochondria-targeted slow H2S releasing donor AP39 on lipopolysaccharide (LPS)-induced airway inflammation were investigated in in vitro and in vivo models. In in vitro model tracheal rings ... -
The Proline-Rich Tetramerization Peptides In Equine Serum Butyrylcholinesterase
(Wiley-Blackwell, 2012)Soluble, tetrameric, plasma butyrylcholinesterase from horse has previously been shown to include a non-covalently attached polyproline peptide in its structure. The polyproline peptide matched the polyproline-rich region ... -
The Scope, Quality And Safety Requirements Of Drug Abuse Testing
(Turkiye Sinir Ve Ruh Sagligi Dernegi, 2017)The aim of this review is to inform about the scopes and requirements of drug abuse testing. Drug abuse testing is one of the tools for determination of drug use. It must fulfill the quality and safety requirements in ... -
The Effect of Low-Dose Methotrexate on Autologous Fat Graft Survival
(Tubitak Scientific & Technical Research Council Turkey, 2016)Background/aim: The survival of autologous fat graft tissue is dependent on various factors such as vascularization and inflammation. The aim of the present study was to evaluate the possible beneficial effects of low-dose ... -
Antioxidant And Cytotoxic Effects Of Moltkia Aurea Boiss
(Acg Publications, 2012)The water extract of M. aurea exhibited strong scavenging effect on 2,2-diphenyl-1-picrylhydrazil (DPPH), nitric oxide (NO) and superoxide (SO) radicals. The free radical scavenging effect of the extract was found comparable ... -
Specimen Rejection In Laboratory Medicine: Necessary For Patient Safety?
(2015)Introduction The emergency laboratory in Hacettepe University Hospitals receives specimens from emergency departments (EDs), inpatient services and intensive care units (ICUs). The samples are accepted according to the ... -
Stereological Analysis Of Sciatic Nerve In Chickens Following Neonatal Pinealectomy: An Experimental Study
(2010)Background Although the injury to the peripheral nervous system is a common clinical problem, understanding of the role of melatonin in nerve degeneration and regeneration is incomplete. Methods The current study investigated ... -
Surface-Modified Bacterial Nanofibrillar Phb Scaffolds for Bladder Tissue Repair
(Taylor & Francis Ltd, 2016)The aim of the study is in vitro investigation of the feasibility of surface-modified bacterial nanofibrous poly [(R)-3-hydroxybutyrate] (PHB) graft for bladder reconstruction. In this study, the surface of electrospun ... -
Simultaneous Spectrophotometric Determination Of Ezetimibe And Simvastatin In Pharmaceutical Preparations Using Chemometric Techniques
(Soc Brasileira Quimica, 2008)Two spectrophotometric methods are described for the simultaneous determination of ezetimibe (EZE) and simvastatin (SIM) in pharmaceutical preparations. The obtained data was evaluated by using two different chemometric ... -
Solid-Phase Enzyme Modification Via Affinity Chromatography
(Elsevier Science Bv, 2003)In the present study antileukemic enzyme L-asparaginase (ASNase) and catalase (as a model enzyme) were modified in solid-phase with activated polyethylene glycol (PEG,) by using ligand-immobilized affinity column systems ... -
Sensitive Adsorptive Voltammetric Method For Determination Of Bisphenol A By Gold Nanoparticle/Polyvinylpyrrolidone-Modified Pencil Graphite Electrode
(2016)A novel electrochemical sensor gold nanoparticle (AuNP)/polyvinylpyrrolidone (PVP) modified pencil graphite electrode (PGE) was developed for the ultrasensitive determination of Bisphenol A (BPA). The gold nanoparticles ... -
Simultaneous Determination Of Ezetimibe And Simvastatin In Pharmaceutical Preparations By Mekc
(Preston Publ Inc, 2010) -
Sedative Effect Of Centranthus Longiflorus Ssp Longiflorus In Rats And The Influence Of Adrenalectomy On Its Effect
(Pharmaceutical Soc Japan, 2007)Sedative effect of the aqueous extract of Centranthus longiflorus ssp. longiflorus (Cle-1) on intact and adrenalectomized rats was investigated using a thiopental sleeping test to clarify the relationship of this effect ... -
Saliva/Serum Ghrelin, Obestatin And Homocysteine Levels In Patients With Ischaemic Heart Disease
(2017)Background: We aimed to compare ghrelin, obestatin, homocysteine (Hcy), vitamin B12 and folate levels in the serum and saliva of ischaemic heart disease patients. Methods: Serum and saliva were collected from 33 ischaemic ...
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