Browsing Eczacılık Fakültesi by Title
Now showing items 36-55 of 126
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Farmasötik Preparatlardan ve Gıdalardan Tobramisin Tayini İçin Moleküler Baskılanmış Nanosensörlerin Geliştirilmesi
(Sağlık Bilimleri Enstitüsü, 2013)In this thesis study, the molecularly imprinted glassy carbon and quartz crystal microbalance (QCM) nanosensors were developed for the determination of tobramycin. For QCM nanosensor, firstly the modification of gold surface ... -
Febril Nötropeni Gelişim Riski Olan ve Granülosit Koloni Stimüle Edici Faktör (G-Csf) Kullanan Kanser Hastalarının Patıent Rısk Score (Prs) ile Takibi ve Yan Etkilerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2018-06)Febrile neutropenia is the most important dose-limiting side effect of chemotherapy. Although the international treatment guidelines recommend prophylactic use of G-CSF in chemotherapy protocols with a risk of febrile ... -
Fenotiyazin Yapılı Bileşiklerin Amiloid Prekürsör Protein ve Amiloid Beta Peptitler Üzerindeki Etkilerinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2017-09)In the present study, we aimed to investigate the effects of two phenothiazine-structured compounds [toluidine blue O (TBO) and thionine (TH)], which were found to be potent inhibitors of human erythrocyte acetylcholinesterase ... -
Fetal Sığır Serum Asetilkolinesterazının Tetramerik Yapısını Organize Eden Poliprolin Peptidlerin Kütle Spektrometre ile Analizi
(Sağlık Bilimleri Enstitüsü, 2014)Acetylcholinesterase (AChE) in the serum of fetal bovine is a tetrameric enzyme. The related enzyme, butyrylcholinesterase (BChE), in the sera of humans and horse requires polyproline peptides for assembly into tetramers. ... -
Flurbiprofenin Sitotoksik, Genotoksik ve Apoptotik Etkilerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2018-11-02)B Bakir, E., Evaluation of Cytotoxic, Genotoxic and Apoptotic Effect of Flurbiprofen, Hacettepe Un¬vers¬ity Graduate School Health Sciences Pharmacy Department of Pharmaceutical Toxicology Doctor of Phi¬losophy Thes¬is, ... -
Geriatri Polikliniği Ve Huzurevi Hastalarının STOPP/START ve MAI Kriterleri ile Değerlendirilmesi ve Müdahalelerin Yapılmasında Klinik Eczacının Rolü
(Sağlık Bilimleri Enstitüsü, 2017-07-13)In this thesis, second version of "Screening Tool of Older People’s Potentially Inappropriate Prescriptions (STOPP)” and " Screening Tool to Alert Doctors to Right Treatment (START)” criteria have been used to determine ... -
Hashimoto Tiroiditinde Selenyum ve Selenoprotein Düzeyleri ile Oksidatif Stres Biyogöstergelerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2015)Hashimoto's thyroiditis (HT) is an autoimmune disease of thyroid gland. In the course of the disease, thyroid gland is attacked by a variety of cell- and antibody-mediated immune processes. It is reported that high iodine ... -
Hedeflendirilmiş Antikanser İlaç Yüklü Polimerik Nanotaşıyıcıların Formülasyonları ve Karakterizasyonları
(Sağlık Bilimleri Enstitüsü, 2019)The distribution of the drugs used in cancer chemotherapy without distinction between the diseased area and the healthy area causes damage to healthy tissue. By using targeted drug delivery systems it is intended to ... -
Hemen Salım Sağlayan Kandesartan Sileksetil Tablet Formülasyonuna Tasarımla Kalite Uygulaması
(Sağlık Bilimleri Enstitüsü, 2013)It was investigated a stable formulation development, process understanding and controlling of immediate release Candesartan Cilexetil 32 mg tablet by using QbD approach. Candesartan Cilexetil is a drug substance ... -
Hepatit B ve C Virüsü ile Enfekte Hastaların Tedavisinde İlaç Kaynaklı Sorunlar
(Sağlık Bilimleri Enstitüsü, 2018)Hepatitis B and C are the leading cause of cirrhosis and hepatocellular carcinoma. A low diagnosis rate and poor access to clinical care are a major risks in hepatitis B and C‐related morbidity and mortality. Lack of ... -
HepG2, Caco-2 ve HT-29 Kanser Hücrelerinde 2D Jel Elektroforez ve MALDI-TOF/TOF-MS) ile Ankaferd Hemostat’ ın İn-Vitro Antineoplastik Etkisinin Proteomik Açıdan Araştırılması
(Sağlık Bilimleri Enstitüsü, 2019)One of the breakthroughs in life sciences has been accomplished through the completion of the human genome project. However, the compose of the entire genome map has also brought a tough task for scientists. This task is ... -
Ht29 Ve K562 Kanser Hücrelerinde Protein Ve Metabolitlerin Analizi Için Çeşitli Analitik Yöntemlerin Geliştirilmesi
(Sağlık Bilimleri Enstitüsü, 2013)Cancer is one of the most dangerous fatal diseases threating the human being both economically and socially. Therefore, the studies are performed on molecular level to understand cancer on molecular level and prevent the ... -
Investigation of Intracellular Mechanisms of Sphingosine-1-Phosphate (S1P)-Induced Contractions in Detrusor Smooth Muscle of Rats having Cyclophosphamide-Induced Cystitis
(Sağlık Bilimleri Enstitüsü, 2017)Anjum I., Investigation of Intracellular Mechanisms of Sphingosine-1-Phosphate (S1P)-Induced Contractions in Detrusor Smooth Muscle of Rats having Cyclophosphamide-Induced Cystitis, Hacettepe University, Institute of Health ... -
Isolatıon of Potentıal Drug Candıdate Molecules from Rumex Acetosella L. and in Sılıco, in Vıtro Researches on Those Molecules
(Sağlık Bilimleri Enstitüsü, 2018)Ozenver, N., Isolation of Potential Drug Candidate Molecules From Rumex acetosella L. and In Silico, In Vitro Researches on Those Molecules, Hacettepe University, Institute of Health Sciences, Pharmacognosy Program, Doctor ... -
İç Hastalıkları Servislerinde Yatan Hastalarda Uygun Olmayan Endikasyonlarda Oral Proton Pompası İnhibitörleri Kullanımının Tespit Edilmesi ve Hasta Uyuncunun Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2017)The use of unnecessary proton pump inhibitors (PPIs) is very common in the world and in our country also. This situation increases the risk of many adverse reactions and drug interactions. For this reason, in order to ... -
İlaç Hammaddesi Kaynağı Bazı Scutellaria L. Türleri Üzerinde Farmakognozik Araştırmalar
(Sağlık Bilimleri Enstitüsü, 2018-01)Genus Scutellaria (Lamiaceae), which includes about 350 species in worldwide, is widespread in Europe, America and East Asia. It is represented by 16 species in the flora of Turkey. Scutellaria species are the most popular ... -
İnsan Nöroblastoma Hücre Kültüründe Amiloid Beta ile Oluşturulan Alzheimer Hastalığı Modelinde Atorvastatinin Sestrin-2, Sirtuin-1, TPP1 ve LC3B Ekspresyonuna Etkisi.
(Sağlık Bilimleri Enstitüsü, 2019-02)Çelik, H. The Effect of Atorvastatin on Sestrin-2, Sirtuin-1, TPP1 and LC3B in Amyloid Beta Induced Alzheimer’s Disease Model in Human Neuroblastoma Cell Culture. Hacettepe University Graduate School of Health Sciences, ... -
İnsan Serum Bütirilkolinesterazı ve Eritrosit Asetilkolinesterazının Statin Türevleri ile Etkileşiminin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2014)To investigate effects of statins on cholinesterases, Butyrylcholinesterase (BChE; E.C.3.1.1.8 ) was purified from human plasma through acid dialysis, DEAE-Tris Acryl M ion exchange and Procainamide-Sepharose 4B chromatography ... -
İnsan Serum Bütirilkolinesterazının Karaciğer Hepg2 Hücrelerinde Lipid Metabolizması ile Etkileşiminin İncelenmesi.
(Sağlık Bilimleri Enstitüsü, 2015)Butyrylcholinesterase (BChE) synthesized in liver is mostly associated with the detoxification of xenobiotics. Recently we have shown that in sedentary young males, application of exercise and/or conjugated linoleic acid ... -
Kanser Tedavisinde Kullanılacak Aktif Hedeflendirilmiş Farmasötik Nano Taşıyıcılar
(Sağlık Bilimleri Enstitüsü, 2012)The use of various targeted nanocarriers has turned out to be one of the most important areas of nanomedicine. These carriers are nanosized materials that can carry various drugs and/or imaging agents. It is also possible ...
