Browsing Eczacılık Fakültesi by Title
Now showing items 365-384 of 468
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Radical Scavenging Effect Of Different Marine Sponges From Mediterranean Coasts
(Acg Publications, 2013)To find new products reducing free radical damage is very important research area in recent pharmaceutical investigations. Considering this information, different marine sponges distributed in Mediterranean coasts of Turkey ... -
Radical Scavenging Effects of Different Veronica Species
(Acg Publications, 2011)It is well known that the excessive production of reactive oxygen species is hazardous for living organisms and damages major cellular constituents such as DNA, lipid and protein. To find new products reducing free radical ... -
Raloksifen'in Biyolojik Materyalden ve Farmasötik Preparattan Analizi İçin Gaz Kromatografisi-Kütle Spektrometrisi Yönteminin Geliştirilmesi ve Valide Edilmesi
(Sağlık Bilimleri Enstitüsü, 2012)Raloxifene is selective estrogen modulator (SERM) drug which is used in the treatment of postmenopausal osteoporosis in women and used for doping in men. A new gas chromatography-mass spectrometry (GC-MS) method was developed ... -
Regeneration and Healing of Bone and Cartilage in Type-1 and Type-2 Diabetes: The Effects of Insulin
(Tubitak Scientific & Technical Research Council Turkey, 2016)Increased fragility of long bones and delay in fracture healing in adults as well as skeletal development disorders in children are thought to be associated with endochondral ossification problems. The extracellular matrix ... -
Rekombinant Granülosit Koloni Uyarıcı Faktörün Biyopolimerlerle Enzimatik Konjugasyonu ve Proteinin Özellikleri Üzerindeki Etkilerinin Araştırılması Üzerinde Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2017)Second generation protein products are studied and products are developed in recent years. Aim of this thesis is to add a new alternative to second generation drug development approaches with filgrastim. For this purpose, ... -
Resveratrol Prevents Dendritic Cell Maturation In Response To Advanced Glycation End Products
(2013)Advanced glycation end products (AGEs), generated through nonenzymatic glycosylation of proteins, lipids, and nucleic acids, accumulate in the body by age thus being considered as biomarkers of senescence. Senescence is ... -
Resveratrol Protects Sepsis-Induced Oxidative DNA Damage in Liver and Kidney of Rats
(Galenos Yayincilik, 2016)Background: The increases of free radicals have been proposed to be involved in the pathogenesis of sepsis, which leads to multiple-organ dysfunction syndromes. The uses of antioxidants as a complementary tool in the medical ... -
Rivaroksaban Nanokristallerinin Hazırlanması ve İn Vitro - İn Vivo Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2018-04-27)The aim of this thesis is to solve the dose-proportionality problem encountered in high doses as a result of low solubility of rivaroxaban (RXB) which is a direct factor Xa inhibitor and a Biopharmaceutical Classification ... -
Role of Serotonin in the Regulation of Renal Proximal Tubular Epithelial Cells
(Taylor & Francis Ltd, 2016)In various renal injuries, tissue damage occurs and platelet activation is observed. Recent studies suggest that some factors, such as serotonin, are released into microenvironment upon platelet activation following renal ... -
Rosa damascena Mill. Farmakope Standartlarının Belirlenmesi, Matriks Metalloproteinaz (MMP) İnhibitör Etkinliklerinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2018-03-08)This thesis is summarized as botanical, phytochemical, analytical and biological activity titles. The morphological and anatomical characteristics of Rosa damascena Mill. (Rosaceae) petals have been described in the botanical ... -
Rostral Ventrolateral Medullary But Not Medullary Lateral Tegmental Field Neurons Mediate Sympatho-Sympathetic Reflexes in Cats
(Amer Physiological Soc, 2010)Barman SM, Orer HS. Rostral ventrolateral medullary but not medullary lateral tegmental field neurons mediate sympatho-sympathetic reflexes in cats. Am J Physiol Regul Integr Comp Physiol 299: R1269-R1278, 2010. First ... -
Rp-Hplc Method Development and Validation for Estimation of Rivaroxaban in Pharmaceutical Dosage Forms
(Univ Sao Paulo, Conjunto Quimicas, 2013)Rivaroxaban, an anti-clotting medication, acts at a crucial point in the blood-clotting process and stops the formation of blood clots. In this study, RP-HPLC method was developed for the determination of rivaroxaban in ... -
Rumex Crıspus L. Ekstreleri ve Sekonder Metabolitlerinin Mmps İnhibitör Aktiviteleri, Antioksidan Kapasiteleri ve Spf Değerlerinin Araştırılarak, Ciltteki Kollajen Dokuyu Onarıcı Fitokozmetik Ürün Geliştirilmesi
(Sağlık Bilimleri Enstitüsü, 2017)Uzun, M., Development of Collagenous Tissue Restorative Phytocosmetics on Skin by Investigation of MMPs Inhibitory Activities, Antioxidant Capacities and Spf Values of Rumex crispus L. Extracts and Sekonder Metabolites, ... -
Rutin Ameliorates Methotrexate Induced Hepatic Injury in Rats
(Acta Cirurgica Brasileira, 2015)PURPOSE: To investigate the possible protective effect of rutin on methotrexate induced hepatotoxicity in rats. METHODS: Twenty-two rats were divided into three experimental groups; Control-saline, Mtx, Mtx+Rutin. Hepatic ... -
S54. The Role Of The Clinical Pharmacist In Drug Education For Increasing Compliance With Drug Therapy In The Period Of Discharge With The Diagnosis Of Schizophrenia Spectrum Disorders
(2018)Background The inability to achieve full compliance with drug treatment during the post-discharge period with exacerbations in the illness in patients with schizophrenia and other psychotic disorders is a major problem for ... -
Saliva/Serum Ghrelin, Obestatin and Homocysteine Levels in Patients With Ischaemic Heart Disease
(2017)Background: We aimed to compare ghrelin, obestatin, homocysteine (Hcy), vitamin B12 and folate levels in the serum and saliva of ischaemic heart disease patients. Methods: Serum and saliva were collected from 33 ischaemic ... -
Sedative Effect of Centranthus Longiflorus Ssp Longiflorus in Rats and the Influence of Adrenalectomy on Its Effect
(Pharmaceutical Soc Japan, 2007)Sedative effect of the aqueous extract of Centranthus longiflorus ssp. longiflorus (Cle-1) on intact and adrenalectomized rats was investigated using a thiopental sleeping test to clarify the relationship of this effect ...