Browsing Eczacılık Fakültesi by Title
Now showing items 100-119 of 126
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Sefiksimin Düşük Çözünürlük ve Permeabilitesinin Siklodekstrin Kompleksleri Kullanılarak Artırılması Üzerine Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2015)Cefixime(SEF) is a wide spectrum antibiotic that is included in the third generation cephalosporins group. Its oral bioavailability is reported to be 40 %. Cyclodextrins have the ability to interact with poorly water-soluble ... -
Sefuroksim Aksetil' in Voltametrik Davranışlarının İncelenmesi ve Elektroanalitik Yöntemlerle Farmasötik Preparatlardan Analizi
(Sağlık Bilimleri Enstitüsü, 2015)In this thesis, square wave voltammetric (SWV) methods have been developed for the quantitative determination of cefuroxime axetil (CEFA) from pharmaceutical preparations. Electrochemical reduction and oxidation of the ... -
Seramik İşçilerinde Mesleki Maruziyete Bağlı Olası Genotoksik Hasarın Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2017)Silicon (Si) is the second most abundant element after oxygen that was mainly found in granite, flint, quartz rocks and stones. Exposure to crystalline silica (SiO2) occurs mainly in foundry, processing of diatomaceous ... -
Serotoninin Renal Hasardaki Rolü
(Sağlık Bilimleri Enstitüsü, 2015)In various acute and chronic renal diseases, tissue damage occurs and platelet activation is observed. Recent studies suggest that some factors released from activated platelets may participate in inflammation and fibrosis ... -
Serviks Kanser Hücre Hattında Timokinonun Sisplatin Sitotoksisitesine Etkilerinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2018)Thymoquinone, derived from the volatile oil of Nigella sativa L. seed known as black seed “çörek otu” in Turkey, is a monoterpene molecule and a bioactive compound. Along with being consumed as food for centuries, thymoquinone ... -
Silikozis Hastalarında Oksisterol Düzeylerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2018)Silicosis is a chronic inflammatory occupational disease that causes permanent and progressive damage to the lungs resulting from prolonged inhalation of silica (SiO2) particles. A significant number of silicosis cases ... -
Sterılızatıon of Grafts Used in Perıodontology by Gamma and Mıcrowave Radıatıon
(Sağlık Bilimleri Enstitüsü, 2018-08-02)BARGH, S, Studies on Sterilization of Grafts Used in Periodontology by Gamma and Microwave Radiation. Hacettepe University, Institute of Health Sciences, Radiopharmacy Program, Master of Science Thesis, Ankara, 2018. The ... -
Studıes on Some Aryloxymethyl Thıosemıcarbazıde, 1,3,4-Thıadıazole And 1,2,4-Trıazole-5-Thıone Derıvatıves
(Sağlık Bilimleri Enstitüsü, 2013)In this study, twelve 1-(7-methoxy-2-naphthyloxyacetyl)-4-subtituted-3-thiosemicarbazide, 5-(7-methoxy-2-naphthyloxymethyl)-2-substituted amino-1,3,4-thiadiazole and 3-(7-methoxy-2-naphthyloxymethyl)-4-substituted- 1,2 ... -
Synthesıs of Condensed 1,4-Dıhydropyrıdıne Derıvatıves And Evaluatıon Of Theır Calcıum Channel Modulatıng and Antıoxıdant Actıvıtıes
(Sağlık Bilimleri Enstitüsü, 2014)In this study, study, a pharmacophore model based on calcium channel blocker ligands was generated by LigandScout and nineteen 2-(methacryloyloxy)ethyl 4-aryl-2,6,6-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate ... -
Sıçan Izole Mezenter Arterinde Kalsiyumsuz Ortamda Elektriksel Alan Uyarısı Ile Elde Edilen Kasılmaların Mekanizmasının Incelenmesi
(Sağlık Bilimleri Enstitüsü, 2014)In the present study, we aimed to examine the effect of blockade of L-type calcium channels (LTCC) and in addition the removal of extracellular calcium, on EFS-induced relaxations in rings of rat mesenteric artery. EFS (30 ... -
Sıçanlarda Adeno İlişkili Viral Vektör Aracılı Gerçekleştirilen Nigral ve Hipokampal Alfasinükleinopati Modelinde Rapamisinin Etkileri
(Sağlık Bilimleri Enstitüsü, 2018)Çınar, E., Effects of Rapamycin In A Rat Model Of Adeno Associated Viral Vector Mediated Nigral and Hippocampal Alpha-synucleinopathy, Hacettepe University Graduate School of Health Sciences, Pharmacology Programme Doctor ... -
Şizofreni ve Benzeri Psikotik Bozukluk Tanısı Almış Hastalara Taburculuk Döneminde İlaç Tedavisine Uyuncunu Arttırmaya Yönelik Olarak Verilen İlaç Eğitiminde Klinik Eczacının Rolü
(Sağlık Bilimleri Enstitüsü, 2017-12-18)The inability to achieve full compliance with drug treatment during the post-discharge period with exacerbations in the illness in patients with schizophrenia and other psychotic disorders is a major problem for the patients ... -
The in Vitro and in Vivo Effects of Telomerase Substrate 6-Thio-2 -Deoxyguanosine
(Sağlık Bilimleri Enstitüsü, 2014)Telomerase mediated telomere targeted therapy represents a new approach in cancer therapy. In this study, I report that the nucleoside analogue 6-thio-2’-deoxyguanosine (6-thio-dG) is recognized by the telomerase ... -
The Protectıve Role Of Escıtalopram On Impared Hıppocampal Neuroplastıcıty Durıng Rem Deprıvatıon
(Sağlık Bilimleri Enstitüsü, 2013)Sleep disorders are mostly associated with psychiatric problems like depression, anxiety disorders, etc. and are thought to be the underlying cause of cognitive deficits observed in these patients. It has been shown that ... -
Tirozin Kinaz İnhibitörleri ile Tedavi Edilen Hastalarda Tedavi İzleminde İlaç Etkileşimleri ve Yan Etkilerin Saptanması ve Önlenmesinde Klinik Eczacının Rolü
(Sağlık Bilimleri Enstitüsü, 2016)The use of tyrosine kinase inhibitors as targeted therapies in cancer treatment becomes prevalent. The aim of this study was to determine and prevent drug-drug interactions and also to reduce side effects of thyrosine ... -
TİROİD HÜCRELERİNDE BİSFENOL A’NIN TOKSİK ETKİLERİ VE SELENYUM BİLEŞİKLERİNİN KORUYUCU ROLÜNÜN DEĞERLENDİRİLMESİ
(Sağlık Bilimleri Enstitüsü, 2019)Bisphenol A (BPA) is a chemical compound that is used in the production of polycarbonates and epoxy resins. Humans are widely exposed to this compound by oral, inhalation and dermal routes in daily life. It is known to ... -
Toxıcologıc Evaluatıon of Sılver Nanopartıcles
(Sağlık Bilimleri Enstitüsü, 2014)Silver nanoparticles (Ag-NPs) are widely applied in several products due to their unique physico-chemical properties as well as bactericidal effects. The extensive application of Ag-NPs has raised concerns about their ... -
Türkiye De Nuts Tr 5 Bölgesinde Esansiyel Hipertansiyon Tedavisinde Sosyal Güvenlik Kurumu Açısından Ilaç Kullanımı ve Tedavi Maliyetinin Retrospektif Veri Tabanı Analizi
(Sağlık Bilimleri Enstitüsü, 2014)Essential hypertension has been the first disease to have the highest drug expenditures from the date of constitution of Social Security Institution. In Turkey, Ministry of Health is aiming to treat and control essential ... -
Türkiye De Piyasalarda Bulunan Bazı Curcuma Longa L. Rizom Ve Preperatları Üzerinde Farmakognozik Ar
(Sağlık Bilimleri Enstitüsü, 2012)Curcuma longa L. rhizomes which are mainly used as spice and for medical purposes in Turkey, are rich in curcumin with (1E, 6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione structure. Three ungrounded rhizomes ... -
Türkiye'de Ekonomik Önemi Olan Bazı Tıbbi Kültür Bitkileri Üzerinde Stabilite ve Biyolojik Aktivite Çalışmaları
(Sağlık Bilimleri Enstitüsü, 2017-07-14)ABSTRACT Gönülalan, E. M. Stability and Biological Activity Studies on Some Medicinal Cultivated Plants with Economic Priority in Turkey, Hacettepe University, Institute of Health Sciences, Pharmacognosy Program, PhD ...
