Browsing Eczacılık Fakültesi by Title
Now showing items 420-439 of 464
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The Effect of Low-Dose Methotrexate on Autologous Fat Graft Survival
(Tubitak Scientific & Technical Research Council Turkey, 2016)Background/aim: The survival of autologous fat graft tissue is dependent on various factors such as vascularization and inflammation. The aim of the present study was to evaluate the possible beneficial effects of low-dose ... -
The Effects of Di(2-Ethylhexyl)Phthalate on Rat Liver in Relation to Selenium Status
(Wiley-Blackwell, 2014)This study was performed to determine the hepatotoxicity of di(2-ethylhexyl)phthalate (DEHP) in relation to selenium status. In 3-week-old Sprague-Dawley rats, selenium deficiency was induced by a 0.05 selenium mg/kg. A ... -
The Effects of Fenvalerate on Hepatic and Cerebral Xenobiotic Metabolizing Enzymes in Selenium and/or Iodine Deficient Rats
(2016)Objective(s): Particularly in developing countries, selenium and/or iodine deficiencies are encountered and use of pesticides in agriculture are not well-controlled. Fenvalerate is a pyrethroid insectide used in agriculture ... -
The in Vitro and in Vivo Effects of Telomerase Substrate 6-Thio-2 -Deoxyguanosine
(Sağlık Bilimleri Enstitüsü, 2014)Telomerase mediated telomere targeted therapy represents a new approach in cancer therapy. In this study, I report that the nucleoside analogue 6-thio-2’-deoxyguanosine (6-thio-dG) is recognized by the telomerase ... -
The Operational Multiple Dosing Half-Life: A Key To Defining Drug Accumulation In Patients And To Designing Extended Release Dosage Forms
(Springer/Plenum Publishers, 2008)Half-life (t (1/2)) is the oldest but least well understood pharmacokinetic parameter, because most definitions are related to hypothetical 1-compartment body models that don't describe most drugs in humans. Alternatively, ... -
The Proline-Rich Tetramerization Peptides In Equine Serum Butyrylcholinesterase
(Wiley-Blackwell, 2012)Soluble, tetrameric, plasma butyrylcholinesterase from horse has previously been shown to include a non-covalently attached polyproline peptide in its structure. The polyproline peptide matched the polyproline-rich region ... -
The Protectıve Role of Escıtalopram on Impared Hıppocampal Neuroplastıcıty Durıng Rem Deprıvatıon
(Sağlık Bilimleri Enstitüsü, 2013)Sleep disorders are mostly associated with psychiatric problems like depression, anxiety disorders, etc. and are thought to be the underlying cause of cognitive deficits observed in these patients. It has been shown that ... -
The Roles Of Valerenic Acid On Bdnf Expression In The Sh-Sy5Y Cell
(Elsevier Science Bv, 2018)The roots of Valeriana officinalis L. (Valerianaceae) are used for treating sleep disorders and/or mild nerve tension. The effect of valerenic acid on brain-derived neurotrophic factor (BDNF) has not yet been studied, ... -
The Sublethal Effects Of (2,4-Dichlorophenoxy) Acetic Acid (2,4-D) On Narrow-Clawed Crayfish (Astacus Leptodactylus Eschscholtz, 1823)
(Inst Medical Research & Occupational Health, 2016)2,4-D is a widely used phenoxy herbicide, potentially toxic to humans and biota. The objective of the present study was to reveal short term sublethal effects of 2,4-D on narrow-clawed freshwater crayfish (Astacus leptodactylus ... -
The Trypsin-Inhibitory Efficiency Of Human Alpha(2)-Macroglobulin In The Presence Of Alpha(1)-Proteinase Inhibitor: Evidence For The Formation Of An Alpha(2)-Macroglobulin-Alpha(1)-Proteinase Inhibitor Complex
(Harwood Acad Publ Gmbh, Taylor & Francis Group, 1999)The inhibition of bovine pancreatic trypsin was studied at pH 7, 25 degrees C, using mixtures of purified human alpha(2)-macroglobulin (alpha(2)M) and alpha(1)-proteinase inhibitor (alpha(1)PI). The partitioning of the ... -
The Use And Importance Of Liposomes In Positron Emission Tomography
(Taylor & Francis Ltd, 2012)Among different imaging modalities, Positron Emission Tomography (PET) gained importance in routine hospital practice depending on ability to diagnose diseases in early stages and tracing of therapy by obtaining metabolic ... -
Three Acylated Flavone Glycosides From Sideritis Ozturkii Aytac & Aksoy
(Pergamon-Elsevier Science Ltd, 2004)From the aerial parts of Sideritis ozturkii, three new flavonoids, chrysoeriol 7-O-[2"'-O-calieoyl-6"'-O-acetyl-beta-D-glucopyranosyl-(1 --> 2)-beta-D-glucopyranoside], chrysoeriol 7-O-[2"'-O-cafeoyl-beta-O-glucopyranosyl-(1 ... -
Thrombus Localization By Using Streptokinase Containing Vesicular Systems
(Taylor & Francis Ltd, 2006)Our research focused on the preparation of vesicular drug delivery systems, such as liposomes, noisomes, and sphingosomes, for achieving slow release of entrapped proteins in the circulation to increase half-life, to mask ... -
Tiroid Hücrelerinde Bisfenol A’nın Toksik Etkileri ve Selenyum Bileşiklerinin Koruyucu Rolünün Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2019)Bisphenol A (BPA) is a chemical compound that is used in the production of polycarbonates and epoxy resins. Humans are widely exposed to this compound by oral, inhalation and dermal routes in daily life. It is known to ... -
Tirozin Kinaz İnhibitörleri ile Tedavi Edilen Hastalarda Tedavi İzleminde İlaç Etkileşimleri ve Yan Etkilerin Saptanması ve Önlenmesinde Klinik Eczacının Rolü
(Sağlık Bilimleri Enstitüsü, 2016)The use of tyrosine kinase inhibitors as targeted therapies in cancer treatment becomes prevalent. The aim of this study was to determine and prevent drug-drug interactions and also to reduce side effects of thyrosine ... -
Total Parenteral Beslenme (Tpn) Çözeltilerini Hazırlamak İçin Kullanılan Bileşenlerde Ve Tpn Çözeltilerinde Olası Alüminyum Kontaminasyonunun Araştırılması
(Sağlık Bilimleri Enstitüsü, 2019)Inorganic toxicity awareness and research has been increasingly echoed in the scientific world with increasing exposure to metals. Aluminum (Al), which is one of the most known metals, has attracted attention with its ... -
Toxicity Of Acrylamide And Evaluation Of Its Exposure In Baby Foods
(Cambridge Univ Press, 2010)Contaminants are a vast subject area of food safety and quality and can be present in our food chain from raw materials to finished products. Acrylamide, an alpha,beta-unsaturated (conjugated) reactive molecule, can be ... -
Toxicological Evaluation Of Weight Loss Patches: Review
(Ortadogu Ad Pres & Publ Co, 2010)Obesity is defined as increased amount of energy sources stored as body fat in mammalians and human beings, to the extent that it may have adverse effects on health. It is very common around the world and a leading cause ... -
Toxıcologıc Evaluatıon of Sılver Nanopartıcles
(Sağlık Bilimleri Enstitüsü, 2014)Silver nanoparticles (Ag-NPs) are widely applied in several products due to their unique physico-chemical properties as well as bactericidal effects. The extensive application of Ag-NPs has raised concerns about their ...
