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    • untranslated

      Bazı 5-Kloro-2-benzoksazolinon Tiyosemikarbazit, 1,3,4-Tiyadiazol ve 1,2,4-Triazol-5-tiyon Türevleri Üzerinde Çalışmalar 

      Koçak, Ebru (Sağlık Bilimleri Enstitüsü, 2018)
      In this study, nineteen new compounds which have 1-[2-(5-chloro-2-benzoxazolinone-3-yl)acetyl]-4-substitutedthiosemicarbazide, 3-[(5-chloro-2-benzoxazolinone-3-yl)methyl]-4-substituted-1H-1,2,4-triazole-5(4H)-thione, ...
    • untranslated

      Bisfenol Türevlerinin Oksidatif Stres Parametreleri Üzerine Etkilerinin HepG2 Hücrelerinde Karşılaştırmalı Olarak Değerlendirilmesi. 

      Özyurt, Büşra (Sağlık Bilimleri Enstitüsü, 2018)
      Bisphenols belong to a chemical group known as diphenylmethanes and widely used in the production of polycarbonate plastics, as basic chemicals in the resin coating of food and beverage tins. These substances are suggested ...
    • untranslated

      Caco2 Kolon Kanseri Hücrelerinde Ultra Performanslı Sıvı Kromatografisi-kütle Spektroskopisi Bazlı Proteomik Çalışmalar 

      Koçak , Engin (Sağlık Bilimleri Enstitüsü, 2017-01)
      Cancer is the one of the most difficult disease to detect and treat. By omic technologies it has been analyzed at molecular level about cancer. Among the omic technologies Proteomic, has been studied intensively worldwide, ...
    • untranslated

      Çinko Oksit ve Bakır Oksit Nanoparçacıklarının in Vitro Sistemler Üzerindeki Toksik Etkilerinin Araştırılması 

      Paslı, Duygu (Sağlık Bilimleri Enstitüsü, 2017-09)
      Zinc oxide (ZnO) and copper oxide (CuO) NPs are commonly used metal nanoparticles with a high toxicity potential. However, information on toxicity mechanisms like other NPs, is limited. In this study, the possible ...
    • untranslated

      Development of Nano-Formulatıons Contaınıng Neuroprotectıve Actıve Ingredıent and Evaluatıon of Effıcıency in Perıpheral Nerve Injury Model 

      Haidar , Mohammad Karim (Sağlık Bilimleri Enstitüsü, 2018-11-13)
      HAIDAR Mohammad Karim, Development of Nano-formulations Containing Neuroprotective Active Ingredient and Evaluation of Efficiency in Peripheral Nerve Injury Model, Hacettepe University Graduate School of Health Sciences, ...
    • untranslated

      Diyabet Hastalarında Pteridinlerin ve İlgili Yolakların Değerlendirilmesi 

      Gürcü , Sinem (Sağlık Bilimleri Enstitüsü, 2018-07-04)
      Gurcu, S., Evaluation of Pteridins and Related Pathways in Diabetes, Hacettepe University Institute of Health Sciences Ph.D. Thesis in Pharmaceutical Toxicology, Ankara, 2018. Pteridins are heterocyclic compounds that play ...
    • untranslated

      Diyabetik Yara Tedavisinde Kullanılmak Üzere Nanopartiküler Statin ve Kök Hücre İçeren Doku İskelelerinin Formülasyonu ve İn Vitro/İn Vivo Değerlendirilmesi 

      ÖRGÜL, Dilara (Sağlık Bilimleri Enstitüsü, 2017)
      Simvastatin has been shown to support wound healing and stem cell treatment efficacy independent of cholesterol-lowering mechanism in recent studies. Under the light of these facts, in order to provide a new treatment approach ...
    • untranslated

      Down Sendromunun Tanısına Yönelik Seçilmiş Metabolitlerin Gaz Kromatografisi Kütle Spektrometrisi ile Tayini 

      ÖZKAN, Ece (Sağlık Bilimleri Enstitüsü, 2017-07-14)
      Down Syndrome is a common genetic disorder arising due to the condition that humans having an additional chromosome within 21st chromosome couple. Metabolomics is identification and quantification of small molecule metabolites ...
    • untranslated

      Endokrı̇n Bozucu Kı̇myasal Maddelere Kombı̇ne Maruzı̇yetı̇n Etkı̇lerinin Hepg2 Hücre Hattında Değerlendı̇rilmesı̇ 

      Özkemahlı, Kübra Gizem (Sağlık Bilimleri Enstitüsü, 2018-04-24)
      Endocrine disruptors are synthetic or natural substances that disrupt the normal functioning of the body by mimicking or blocking hormones. They are suggested to affect many basic periods and characteristics like growth, ...
    • untranslated

      Evaluatıon of Developmental Toxıcıty of Ethephon Usıng Embryonıc Stem Cell Model 

      Mohammad Nejad, Solmaz (Sağlık Bilimleri Enstitüsü, 2018-09-19)
      Mohammadi Nejad S. Evaluation of Developmental Toxicity of Ethephon Using Embryonic Stem Cell Model. Hacettepe University, Graduate School of Health Sciences, Pharmaceutical Toxicology Program, Doctor of Philosophy Thesis, ...
    • untranslated

      İlaç Hammaddesi Kaynağı Bazı Scutellaria L. Türleri Üzerinde Farmakognozik Araştırmalar 

      Doğan, Zeynep (Sağlık Bilimleri Enstitüsü, 2018-01)
      Genus Scutellaria (Lamiaceae), which includes about 350 species in worldwide, is widespread in Europe, America and East Asia. It is represented by 16 species in the flora of Turkey. Scutellaria species are the most popular ...
    • untranslated

      Meme Kanseri Tedavisinde Aktif Hedeflendirme Amacıyla Kullanılmak Üzere Nano Boyutlu İlaç Taşıyıcı Sistemlerin (Nanofarmasötikler) Tasarımı, İn Vitro/İn Vivo Değerlendirilmesi 

      Timur, Selin Seda (Sağlık Bilimleri Enstitüsü, 2017-09-15)
      The aim of an ideal therapy using anticancer molecules is to target tumors selectively without damaging healthy tissues. Tumor specific markers formed by the physiological and morphological changes during the growth of ...
    • untranslated

      Phytochemıcal and Pharmacologıcal Studıes on Some Papaver Specıes in Turkey 

      BAYAZEID, Omer (Sağlık Bilimleri Enstitüsü, 2017-08-14)
      Papaver species have been used for treating varieties of diseases including depression for centuries in Anatolia. We screened five Papaver species plant extracts for their antidepressant-like activity in vivo and their ...
    • untranslated

      Prenatal Bisfenol A ve/veya Di-2-Etil Hekzil Ftalat Maruziyetinin Erkek Üreme Sistemi Üzerine Etkilerinin İncelenmesi. 

      Balcı, Aylin (Sağlık Bilimleri Enstitüsü, 2018-01)
      Bisphenol A (BPA) and di (2-ethylhexyl) phthalate (DEHP) are chemical substances that are used in a wide variety of industrial products, with proven endocrine disrupting properties. Today, with the increasing use of these ...
    • untranslated

      Pterjiumda Neopterin Düzeylerinin ve Kinürenin Yolağının Değerlendirilmesi 

      KILIÇARSLAN, BİLGE (Sağlık Bilimleri Enstitüsü, 2018)
      Kilicarslan B., Evaluation of Neopterin Levels and Kynurenine Pathway in Pterygium, Hacettepe University Institute of Health Sciences Ph.D. Thesis in Pharmaceutical Toxicology, Ankara, 2018. Pterjium is an inflammatory and ...
    • untranslated

      Rosa damascena Mill. Farmakope Standartlarının Belirlenmesi, Matriks Metalloproteinaz (MMP) İnhibitör Etkinliklerinin Araştırılması 

      Ağar, Osman Tuncay (Sağlık Bilimleri Enstitüsü, 2018-03-08)
      This thesis is summarized as botanical, phytochemical, analytical and biological activity titles. The morphological and anatomical characteristics of Rosa damascena Mill. (Rosaceae) petals have been described in the botanical ...
    • untranslated

      Silikozis Hastalarında Oksisterol Düzeylerinin Değerlendirilmesi 

      Aksu, Neslihan (Sağlık Bilimleri Enstitüsü, 2018)
      Silicosis is a chronic inflammatory occupational disease that causes permanent and progressive damage to the lungs resulting from prolonged inhalation of silica (SiO2) particles. A significant number of silicosis cases ...
    • untranslated

      Türkiye'de Ekonomik Önemi Olan Bazı Tıbbi Kültür Bitkileri Üzerinde Stabilite ve Biyolojik Aktivite Çalışmaları 

      Gönülalan, Ekrem Murat (Sağlık Bilimleri Enstitüsü, 2017-07-14)
      ABSTRACT Gönülalan, E. M. Stability and Biological Activity Studies on Some Medicinal Cultivated Plants with Economic Priority in Turkey, Hacettepe University, Institute of Health Sciences, Pharmacognosy Program, PhD ...
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