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Investigation of 1377C/T Polymorphism of the Toll-Like Receptor 3 Among Patients with Chronic Hepatitis B
(Canadian Science Publishing, Nrc Research Press, 2016)
The immunopathogenesis of chronic hepatitis B (CHB) has not been clarified yet. Toll-like receptors (TLR) are a receptor family that initiates immunity with exogenous-endogenous ligands and plays a role in the pathogenesis ...
Inhibitory Effect Of The Methanolic Extract Of Verbascum Latisepalum Hub.-Mor. On Endothelium-Dependent Relaxation In Rat Thoracic Aorta
(Walter De Gruyter Gmbh, 2014)
The leaves and flowers of Verbascum species are used to treat respiratory disorders, haemorrhoids, rheumatic pain, and wounds as well as for the treatment of eczema and other types of inflammatory skin conditions in ...
Folate, Neopterin And Kynurenine Pathway In Patients With Statin Therapy
(Walter De Gruyter Gmbh, 2016)
Statins, widely used antihyperlipidemic drugs, also have immunomodulatory properties independent from their lipid lowering effect. Even with slight modulations in the immune system, pteridine levels can display changes. ...
Low Doses Of Selenium Specifically Stimulate The Repair Of Oxidative Dna Damage In Lncap Prostate Cancer Cells
(Informa Healthcare, 2012)
Epidemiological studies have demonstrated an inverse relationship between selenium (Se) intake and cancer incidence and/or mortality. However, the molecular mechanisms underlying the cancer chemopreventive activity of Se ...
Low Dose Simvastatin Induces Compositional, Structural and Dynamic Changes in Rat Skeletal Extensor Digitorum Longus Muscle Tissue
(Portland Press Ltd, 2010)
Statins are commonly used drugs in the treatment of hypercholesterolaemia. There are many adverse effects of statins on skeletal muscle, but the underlying mechanisms remain unclear. In the present study, the effects of ...
Curcumin-Based Pyrazoline Analogues As Selective Inhibitors Of Human Monoamine Oxidase A
(Royal Soc Chemistry, 2018)
A series of 2-methoxy-4-(5-phenyl-4,5-dihydro-1H-pyrazol-3-yl)phenol (pyrazoline) derivatives (2-6) have been synthesized and tested for human monoamine oxidase (hMAO) inhibitory activity. The most active derivative (2) ...
Differential Requirement For The Atpase Domain Of The Cockayne Syndrome Group B Gene In The Processing Of Uv-Induced Dna Damage And 8-Oxoguanine Lesions In Human Cells
(Oxford Univ Press, 2002)
Cockayne syndrome (CS) is a rare inherited human genetic disorder characterized by UV sensitivity, developmental abnormalities and premature aging. The cellular and molecular phenotypes of CS include increased sensitivity ...
Effects Of Cadmium And Zinc Ions On Purified Lamb Kidney Cortex Glucose-6-Phosphate Dehydrogenase Activity
(Taylor & Francis Ltd, 2006)
Glucose-6-phosphate dehydrogenase (G-6-PD) is the first enzyme in the pentose phosphate pathway. Cadmium is a toxic heavy metal that inhibits several enzymes. Zinc is an essential metal but overdoses of zinc have toxic ...
Misincorporation Of Free M-Tyrosine Cytotoxic Mechanism For Oxidized A Into Cellular Proteins: A Potential Amino Acids
(Portland Press Ltd, 2006)
In vitro studies demonstrate that the hydroxyl radical converts L-phenylalanine into in-tyrosine, an unnatural isomer of L-tyrosine. Quantification of m-tyrosine has been widely used as an index of oxidative damage in ...
An Artificial Intelligent Diagnostic System on Differential Recognition of Hematopoietic Cells From Microscopic Images
(Wiley-Liss, 1997)
Despite their advantages, none of the automated white blood cell differential counters have replaced the conventional microscopic evaluations of blood and bone marrow slides by hematologists, We have analyzed the smears ...
