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Proguanil Metabolism in Relation To S-Mephenytoin Oxidation in A Turkish Population

Basci, NE; Bozkurt, A; Kortunay, S; Isimer, A; Sayal, A; Kayaalp, SO (Blackwell Science Ltd, 1996)

The oxidation of proguanil was studied in 89 unrelated healthy Turkish volunteers after administration of proguanil (single dose, 200 mg, orally). Based on the distribution of the ratio of proguanil to cycloguanil excreted ...

Cyp2C19 Genotype Does Not Represent A Genetic Predisposition In Idiopathic Systemic Lupus Erythematosus

Kortunay, S; Bozkurt, A; Bathum, L; Basci, NE; Calguneri, M; Brosen, K; Kayaalp, SO (British Med Journal Publ Group, 1999)

Background-The aetiology of systemic lupus erythematosus (SLE) is still unknown. In several cases, however, chemicals or drugs were identified as aetiological agents and associations with certain phenotypes of drug ...