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Deneysel Diyabet Modelinde Hipergliseminin Alzheimer Hastalığı ile İlişkili Proteinler Üzerine Etkisi
(Sağlık Bilimleri Enstitüsü, 2016-12)
Diabetes mellitus (DM) which is one of the foremost health problems enhances the risk of Alzheimer’s disease (AD) although the molecular mechanisms behind this association remain unclear. In the present study, selective ...
Fenotiyazin Yapılı Bileşiklerin Amiloid Prekürsör Protein ve Amiloid Beta Peptitler Üzerindeki Etkilerinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2017-09)
In the present study, we aimed to investigate the effects of two phenothiazine-structured compounds [toluidine blue O (TBO) and thionine (TH)], which were found to be potent inhibitors of human erythrocyte acetylcholinesterase ...