Eczacılık Meslek Bilimleri Bölümü
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Kurşun Maruziyeti ve Şelasyon Tedavisi Sonrası Metabolomik ve Lipidomik Analizler
(Sağlık Bilimleri Enstitüsü, 2021)Lead is a widely preferred heavy metal in the industry due to its useful physicochemical properties and it has important toxic effects. Chelation agents are used in its treatment and intravenous sodium calcium edta is one ... -
Potentilla speciosa Willd. var. speciosa Willd. ve sekonder metabolitlerinin α-glukozidaz ve tirosinaz inhibitör etkilerinin araştırılması
(Sağlık Bilimleri Enstitüsü, 2021)Özgünseven, A., Investigation of α-glucosidase and tyrosinase inhibitory effects of Potentilla speciosa Willd. var. speciosa Willd. and its secondary metabolites, Hacettepe University, Graduate School Health Sciences, ... -
Evaluation of Oxidative and Antioxidative Parameters in Pediatric Hematopoietic SCT Patients
(Springer Nature, 2012)Conditioning regimens preceding hematopoietic SCT (HSCT) usually consist of high-dose chemotherapy. Chemotherapy and radiation therapy are associated with increased formation of free radicals and depletion of critical ... -
Antimikobakteriyel Aktivite Göstermesi Beklenen Bazı 2,3-Disübstitüe-5-Metil-4-Tiyazolidinon Türevleri Üzerinde Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2019-09-07)Ekinci, A. S., Studies on Some 2,3-Disubstituted-5-Methyl-4-Thiazolidinone Derivatives Expected to Show Antimycobacterial Activity, Hacettepe University Graduate School of Health Sciences, MS Thesis in Pharmaceutical ... -
Halk İlacı ve Gıda Olarak Kullanılan Prunus Mahaleb L. Tohum ve Meyve Kabuklarında Farmakognozik Araştırmalar
(Sağlık Bilimleri Enstitüsü, 2020)Prunus mahaleb L. (syn. Cerasus mahaleb L. Mill.), a member of medicinal plant kingdom, is known as mahlep, mehlep, idris ağac or pis agac and the seeds used as food and exported. In the present study, In our thesis, ... -
Dibutil Ftalatın İnsan Akciğer Hücre Hattına Toksik Etkilerinin Değerlendirilmesi ve Askorbik Asit ve N-Asetilsisteinin Olası Koruyucu Etkileri
(Sağlık Bilimleri Enstitüsü, 2020)Endocrine disruptings are chemical substances which are generally produced by humans that disrupt the normal functioning of the body by imitating or blocking hormones. The mostly studied phthalate derivative is ... -
Assessment Of Genotoxic Effects Of Pendimethalin In Chinese Hamster Over Cells By The Single Cell Gel Electrophoresis (Comet) Assay
(Turkish Pharmacists Association, 2017)Objectives: Pendimethalin (N-(1-ethylpropyl)-3,4-dimethyl-2,6-dinitrobenzeneamine) is a dinitroaniline herbicide compound which selectively controls weeds. It is a cell division and growth inhibitor. It descends plants in ... -
Kanser Hastalarında Tromboz Riskinin ve Antikoagülan Tedavinin Rehbere Uygunluğunun Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2020-01-15)Cancer patients are at high risk for venous thromboembolism (VTE) and cancer-associated VTE is a major health problem due to its effects on deterioration of disease prognosis, increased treatment costs and delayed cancer ... -
Kanser Hastalarının Opioid Analjezik Kullanımına İlişkin Görüşlerinin Değerlendirilmesi ve Hasta Eğitiminde Klinik Eczacının Rolü
(Sağlık Bilimleri Enstitüsü, 2020)Pain is a common syndrome among cancer patients that has a negative impact on the physiological functions, psychological well-being, quality of life of patients, and that also requires a good management. Patients and their ... -
Farelerde lipopolisakkarit ile indüklenen solunum yolu inflamasyonunda mitokondriye hedeflendirilmiş yavaş hidrojen sülfür salıveren AP39'un ve nitrik oksit sentaz inhibitörü asimetrik dimetil arjinin (ADMA)'nın etkilerinin araştırılması
(Sağlık Bilimleri Enstitüsü, 2019)In this study, the effects of mitochondria-targeted slow H2S releasing donor AP39 on lipopolysaccharide (LPS)-induced airway inflammation were investigated in in vitro and in vivo models. In in vitro model tracheal rings ... -
Microwave-Assisted Synthesis Of Condensed 1,4-Dihydropyridines As Potential Calcium Channel Modulators
(Scientific Technical Research Council Turkey-Tubitak, 2015)This study reports the design, synthesis, and calcium channel modulatory activity evaluation of a series of 14 novel fused 1,4-dihydropyridine derivatives. The molecular design of the compounds was based on modifications ... -
Low Doses Of Selenium Specifically Stimulate The Repair Of Oxidative Dna Damage In Lncap Prostate Cancer Cells
(Informa Healthcare, 2012)Epidemiological studies have demonstrated an inverse relationship between selenium (Se) intake and cancer incidence and/or mortality. However, the molecular mechanisms underlying the cancer chemopreventive activity of Se ... -
Lycopene Restores Trace Element Levels in Ochratoxin A-Treated Rats
(Inst Medical Research & Occupational Health, 2017)This study was designed to investigate the in vivo effects of ochratoxin A (OTA) and/or lycopene on the levels of selenium, zinc, and copper in the liver, kidneys, and testes of male Sprague-Dawley rats. The rats were ... -
Luddin Type Anthraquinone Glycosides from Putoria Calabrica
(Pharmaceutical Soc Japan, 2002)Two new lucidin type anthraquinone glycosides, putorinoside A (1) and putorinoside B (2) were isolated from Putoria calabrica, in addition to two known anthraquinone glycosides, lucidin 3-O-beta-glucopyranoside (3) and ... -
Low Dose Simvastatin Induces Compositional, Structural and Dynamic Changes in Rat Skeletal Extensor Digitorum Longus Muscle Tissue
(Portland Press Ltd, 2010)Statins are commonly used drugs in the treatment of hypercholesterolaemia. There are many adverse effects of statins on skeletal muscle, but the underlying mechanisms remain unclear. In the present study, the effects of ... -
Isolation And Structure Elucidation Of Uncommon Secondary Metabolites From Cistus Salviifolius L.
(Acg Publications, 2015)To our knowledge this is the first report on the isolation of a flavonoid glycoside: quercetin 3-O-alpha-arabinopyranoside (5), two phenylbutanon glycosides: 4-(4'-O-[6''-O-galloyl-beta-galactopyranosyl]-3'-hydroxyphenyl ... -
Leadership and Healthcare Services
(Intech Europe, 2017)The reasons why organizations make changes in various fields, especially in their structure, include various changing situations such as globalization, increasing awareness in human rights and employee rights, developments ...
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