Eczacılık Meslek Bilimleri Bölümü
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KOJİK ASİT TÜREVİ BİLEŞİKLERİN TASARIMI, SENTEZİ VE MELANOMA HÜCRESİNE KARŞI SİTOTOKSİSİTELERİ İLE TİROZİNAZ İNHİBİSYONU ETKİLERİNİN DEĞERLENDİRİLMESİ
(Sağlık Bilimleri Enstitüsü, 2019)Tyrosinase is an enzyme that acts as a catalyst in the biosynthesis of melanin pigment, which is found in fungi, in plants and in animals. Overproduction and accumulation of this pigment causes hyperpigmentation, post ... -
BAZI 2-SÜBSTİTÜE-1H-BENZİMİDAZOL TÜREVLERİ ÜZERİNDE ÇALIŞMALAR
(Sağlık Bilimleri Enstitüsü, 2019)In this study, 12 (1 of registered in the literature) 2-(1H-benzo[d]imidazol-2-yl)-3-(4-(4-substitutedpiperazin-1- yl)phenyl)acrylonitrile (3a-l) and 3 2-(1H-benzo[d]imidazol-2-yl)-3-(4-(4- substitutedpiperazin-1-yl)p ... -
Afyonkarahisar İli Jeotermal Su Kaynaklarından İzole Edilen Mikroalgal Türler Üzerinde Farmakognozik Araştırmalar
(Sağlık Bilimleri Enstitüsü, 2020)Sensoy, M., Pharmacognosic Researches on Isolated Microalgal Species from Geothermal Springs of Afyonkarahisar Province, Hacettepe University, Graduate School of Health Sciences, Pharmacognosy Programme Master of Science ... -
Tiroid Hücrelerinde Bisfenol A’nın Toksik Etkileri ve Selenyum Bileşiklerinin Koruyucu Rolünün Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2019)Bisphenol A (BPA) is a chemical compound that is used in the production of polycarbonates and epoxy resins. Humans are widely exposed to this compound by oral, inhalation and dermal routes in daily life. It is known to ... -
Türkiye'de Yetişen Bazı Acanthus L. Türlerinden İlaç Adayı Bileşiklerin İzolasyonu
(Sağlık Bilimleri Enstitüsü, 2019)Sarikaya Aydin, S., Isolation of Drug Candidate Compounds from Some Acanthus L. Species Growing in Turkey, Hacettepe University, Graduate School of Health Sciences, Pharmacognosy Program, Doctor of Philosophy Thesis, ... -
İnsan Nöroblastoma Hücre Kültüründe Amiloid Beta ile Oluşturulan Alzheimer Hastalığı Modelinde Atorvastatinin Sestrin-2, Sirtuin-1, TPP1 ve LC3B Ekspresyonuna Etkisi.
(Sağlık Bilimleri Enstitüsü, 2019-02)Çelik, H. The Effect of Atorvastatin on Sestrin-2, Sirtuin-1, TPP1 and LC3B in Amyloid Beta Induced Alzheimer’s Disease Model in Human Neuroblastoma Cell Culture. Hacettepe University Graduate School of Health Sciences, ... -
Yağ Asidi Amid Hidrolaz (Faah) ve Monoaçil Gliserol Lipaz (Magl) İnhibitörlerinin Farede Deneysel Solunum Yolu İnflamasyonu Üzerindeki Etkileri
(Sağlık Bilimleri Enstitüsü, 2019-01-15)The endocannabinoid system is a modulator of physiological functions in various biological systems including the airways. In the present study the effects of treatment with the inhibitors of endocannabinoid-degrading enzymes ... -
Flurbiprofenin Sitotoksik, Genotoksik ve Apoptotik Etkilerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2018-11-02)B Bakir, E., Evaluation of Cytotoxic, Genotoxic and Apoptotic Effect of Flurbiprofen, Hacettepe Un¬vers¬ity Graduate School Health Sciences Pharmacy Department of Pharmaceutical Toxicology Doctor of Phi¬losophy Thes¬is, ... -
Türkiye'de Faaliyet Gösteren İlaç Firmalarının Web Siteleri Üzerine Bir Araştırma
(Sağlık Bilimleri Enstitüsü, 2018-10-17)Kayıran, B., A Study on Web Sites of Drug Companies in Turkey, Hacettepe University Graduate School of Health Sciences Master Thesis in Pharmacy Management and Legislation. Ankara, 2018. The Internet, which has been in use ... -
Prenatal Bisfenol A ve/veya Di-2-Etil Hekzil Ftalat Maruziyetinin Nöroendokrin Bozucu Etkilerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2018)Bisphenol A (BPA) and di(2-ethylhexyl) phthalate (DEHP) are chemical substances that are widely present in the environment and known to have endocine disrupting properties. In the recent years, studies have been conducted ... -
Bazı Benzotiyazol Türevleri Üzerinde Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2018)In this study, fifteen 2-(4-substitutedphenyl)benzo[d]thiazole derivatives carrying substituted piperazine and azole moities at the 4 position of phenyl ring were synthesized, of which two had been reported in literature ... -
Hepatit B ve C Virüsü ile Enfekte Hastaların Tedavisinde İlaç Kaynaklı Sorunlar
(Sağlık Bilimleri Enstitüsü, 2018)Hepatitis B and C are the leading cause of cirrhosis and hepatocellular carcinoma. A low diagnosis rate and poor access to clinical care are a major risks in hepatitis B and C‐related morbidity and mortality. Lack of ... -
Pitavastatin Sitotoksisitesinin Serviks Kanser Hücre (Hela) Hattında Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2018)Cervical cancer which is one of the most common cancer types in women throughout the world. Investigation of possible and alternative treatment methods of cervical cancer will lead to the discovery of new effective treatment ... -
Verbascum pyramidatum Bieb. Üzerinde Farmakognozik Araştırmalar
(Sağlık Bilimleri Enstitüsü, 2018)In this research, Verbascum pyramidatum which is used for hemorrhoid and rheumatism treatment in Turkish folk medicine has been investigated. The air dried and powdered flowers and leaves of the plant were extracted with ... -
Kaynak İşçilerinde Mesleki Maruziyete Bağlı Olası Toksik Etkilerin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2018-07-27)Aksu, İ., Evaluation of Possible Genotoxic Damage in Welders Due to Occupational Exposure, Hacettepe University Institute of Health Sciences, Ph.D. Thesis in Pharmaceutical Toxicology, Ankara, 2018. Welding is widely applied ... -
Metforminin Sitotoksik, Apoptotik ve Genotoksik Etkilerinin İn Vitro Değerlendirilmesi.
(Sağlık Bilimleri Enstitüsü, 2018)Metformin is a biguanide derivative widely used in the treatment of diabetes mellitus. Recent studies have shown the anticancer properties of metformin. The possible mechanisms of anticancer effects of metformin have ... -
Kaynak İşçilerinde Mesleki Maruziyete Bağlı Olası Oksidatif Stres Göstergelerindeki Değişikliklerin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2018-07-05)In recent years, the welding, which is an easier and faster technique than the mechanical methods in cutting and joining metals, is widely used by the manufacturers and repairers. The main potential hazards in welding are; ... -
Silikozis Hastalarında Oksisterol Düzeylerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2018)Silicosis is a chronic inflammatory occupational disease that causes permanent and progressive damage to the lungs resulting from prolonged inhalation of silica (SiO2) particles. A significant number of silicosis cases ... -
Nöropatik Ağrı Tedavisinde İlaç Kullanımının Klinik Eczacı Tarafından İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2018)Neuropathic pain is a chronic problem which requires multidisciplinary approaches for its management. Patients’ adherence to and satisfaction with drug therapies affect the success of pain management which can be improved ... -
Febril Nötropeni Gelişim Riski Olan ve Granülosit Koloni Stimüle Edici Faktör (G-Csf) Kullanan Kanser Hastalarının Patıent Rısk Score (Prs) ile Takibi ve Yan Etkilerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2018-06)Febrile neutropenia is the most important dose-limiting side effect of chemotherapy. Although the international treatment guidelines recommend prophylactic use of G-CSF in chemotherapy protocols with a risk of febrile ...
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