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Pterjiumda Neopterin Düzeylerinin ve Kinürenin Yolağının Değerlendirilmesi

KILIÇARSLAN, BİLGE (Sağlık Bilimleri Enstitüsü, 2018)

Kilicarslan B., Evaluation of Neopterin Levels and Kynurenine Pathway in Pterygium, Hacettepe University Institute of Health Sciences Ph.D. Thesis in Pharmaceutical Toxicology, Ankara, 2018. Pterjium is an inflammatory and ...

Intracellular Generation of Ros by 3,5-Dimethylaminophenol: Persistence, Cellular Response, and Impact of Molecular Toxicity

Chao, Ming-Wei; Erkekoglu, Pinar; Tseng, Chia-Yi; Ye, Wenjie; Trudel, Laura J.; Skipper, Paul L.; Tannenbaum, Steven R.; Wogan, Gerald N. (Oxford Univ Press, 2014)

Epidemiological studies have demonstrated extensive human exposure to the monocyclic aromatic amines, particularly to 3,5-dimethylaniline, and found an association between exposure to these compounds and risk for bladder ...

Immunomodulation And Oxidative Stress In Denim Sandblasting Workers: Changes Caused By Silica Exposure

Palabiyik, Saziye Sezin; Girgin, Gozde; Tutkun, Engin; Yilmaz, Omer Hinc; Baydar, Terken (Inst Medical Research & Occupational Health, 2013)

Workers in denim sandblasting are at a high risk of developing silicosis, an occupational lung disease caused by inhaling crystalline silica dust. The development and progress of silicosis is associated with the activation ...

Induction Of Ros, P53, P21 In Dehp- And Mehp-Exposed Lncap Cells-Protection By Selenium Compounds

Erkekoglu, P.; Rachidi, W.; Yuzugullu, O. G.; Giray, B.; Ozturk, M.; Favier, A.; Hincal, F. (Pergamon-Elsevier Science Ltd, 2011)

This study was designed to investigate the hypothesis that the toxic effects of di(2-ethylhexyl)phthalate (DEHP), the most abundantly used plasticizer and ubiquitous environmental contaminant that cause alterations in ...

Lycopene Restores Trace Element Levels in Ochratoxin A-Treated Rats

Palabiyik, Saziye Sezin; Erkekoglu, Pinar; Kizilgun, Murat; Sahin, Gonul; Kocer-Gumusel, Belma (Inst Medical Research & Occupational Health, 2017)

This study was designed to investigate the in vivo effects of ochratoxin A (OTA) and/or lycopene on the levels of selenium, zinc, and copper in the liver, kidneys, and testes of male Sprague-Dawley rats. The rats were ...

Evaluation Of Cytotoxicity And Oxidative Dna Damaging Effects Of Di(2-Ethylhexyl)-Phthalate (Dehp) And Mono(2-Ethylhexyl)-Phthalate (Mehp) On Ma-10 Leydig Cells And Protection By Selenium

Erkekoglu, Pinar; Rachidi, Walid; Yuzugullu, Ozge Gursoy; Giray, Belma; Favier, Alain; Ozturk, Mehmet; Hincal, Filiz (Academic Press Inc Elsevier Science, 2010)

Di(2-ethylhexyl)-phthalate (DEHP) is the most abundantly used phthalate derivative, inevitable environmental exposure of which is suspected to contribute to the increasing incidence of testicular dysgenesis syndrome in ...

Protective Effects of Ascorbic Acid Against the Genetic and Epigenetic Alterations Induced By 3,5-Dimethylaminophenol in Aa8 Cells

Chao, Ming-Wei; Erkekoglu, Pinar; Tseng, Chia-Yi; Ye, Wenjie; Trudel, Laura J.; Skipper, Paul L.; Tannenbaum, Steven R.; Wogan, Gerald N. (Wiley-Blackwell, 2015)

Exposure to monocyclic aromatic alkylanilines (MAAs), namely 2,6-dimethylaniline (2,6-DMA), 3,5-dimethylaniline (3,5-DMA) and 3-ethylaniline (3-EA), was significantly and independently associated with bladder cancer ...

İnsan Mide Adenokarsinoma Hücrelerinde Helicobacter Pylori'nin Neden Olduğu DNA Çift Sarmal Kırıkları ve Oksidatif Stresin Değerlendirilmesi

Oral, Didem (Sağlık Bilimleri Enstitüsü, 2019-09-27)

Didem, O. Evaluation of DNA Double-Strand Breaks and Oxidative Stress caused by Helicobacter pylori in Human Adenogastric Carcinoma Cells. Hacettepe University Graduate School of Health Sciences, Pharmaceutical Toxicology ...