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Modulation Of The Poly (Adp-Ribose) Polymerase Inhibitor Response And Dna Recombination In Breast Cancer Cells By Drugs Affecting Endogenous Wild-Type P53
(Oxford Univ Press, 2014)
Synthetic lethal interactions between poly (ADP-ribose) polymerase (PARP) and homologous recombination (HR) repair pathways have been exploited for the development of novel mono-and combination cancer therapies. The tumor ...