Eczacılık Teknolojisi Bölümü
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Determination Of Regional Intestinal Permeability Of Diclofenac And Metoprolol Using A Newly-Developed And Validated High Performance Liquid Chromatographic Method
(Pharmacotherapy Group, 2015)Purpose: To develop a simple and rapid reversed-phase high performance liquid chromatographic (HPLC) method with UV detection for the simultaneous determination of diclofenac, metoprolol tartrate, phenol red and propyl ... -
Design And Characterization Of Nanocrystal Formulations Containing Ezetimibe
(Pharmaceutical Soc Japan, 2011)Ezetimibe is a lipid-lowering compound that selectively inhibits the absorption of cholesterol and related phytosterols from the intestine As ezetimibe is almost Insoluble in water, its bioavailability is too low to be ... -
Dendrimeric Systems And Their Applications In Ocular Drug Delivery
(2013)Ophthalmic drug delivery is one of the most attractive and challenging research area for pharmaceutical scientists and ophthalmologists. Absorption of an ophthalmic drug in conventional dosage forms is seriously limited ... -
Comparison Of Dissolution Profiles Of Commercially Available Lamivudine Tablets
(Dissolution Technologies, Inc, 2015)The aim of this study was to investigate the influence of dissolution medium on the in vitro release of lamivudine (100 mg) from four commercially available lamivudine tablets (one reference and three generic). Three ... -
Characterization Of Protein And Peptide Binding To Nanogels Formed By Differently Charged Chitosan Derivatives
(2013)Chitosan (Chi) is a natural biodegradable cationic polymer with remarkable potency as a vehicle for drug or vaccine delivery. Chi possesses multiple groups, which can be used both for Chi derivatization and for particle ... -
Two Percent Chitosan Mouthwash: A Microbiological And Clinical Comparative Study
(Elsevier Taiwan, 2012)Background/purpose: The aim of this study was to evaluate the microbiological and clinical effects of a chitosan (CH) mouth rinse on plaque inhibition. Materials and methods: Thirty-six healthy participants were recruited. ... -
The Operational Multiple Dosing Half-Life: A Key To Defining Drug Accumulation In Patients And To Designing Extended Release Dosage Forms
(Springer/Plenum Publishers, 2008)Half-life (t (1/2)) is the oldest but least well understood pharmacokinetic parameter, because most definitions are related to hypothetical 1-compartment body models that don't describe most drugs in humans. Alternatively, ... -
Thrombus Localization By Using Streptokinase Containing Vesicular Systems
(Taylor & Francis Ltd, 2006)Our research focused on the preparation of vesicular drug delivery systems, such as liposomes, noisomes, and sphingosomes, for achieving slow release of entrapped proteins in the circulation to increase half-life, to mask ... -
An Overview On Dry Eye Treatment: Approaches For Cyclosporin A Delivery
(2012)Dry eye syndrome (DES, Keratoconjunctivitis sicca) is a common disorder of the tear film caused by decreased tear production or increased evaporation. Changes in tear composition also promote inflammation on the ocular ... -
Preparation And Physicochemical Characterizations Of Solid Lipid Nanoparticles Containing Dotap For Dna Delivery
(Scientific Technical Research Council Turkey-Tubitak, 2015)The aim of this study was to prepare and evaluate stable cationic solid lipid nanoparticles (SLNs) as colloidal carriers for gene therapy. SLNs were mainly composed of three different biocompatible and biodegradable matrix ... -
Preparation And In Vitro/In Vivo Evaluation Of Microparticle Formulations Containing Meloxicam
(Springer, 2012)In this study, we have formulated chitosan-coated sodium alginate microparticles containing meloxicam (MLX) and aimed to investigate the correlation between in vitro release and in vivo absorbed percentages of meloxicam. ... -
Preparation And Characterization Of Salmon Calcitonin-Biotin Conjugates
(Springer, 2008)This study was performed to prepare and characterize the biotinylated Salmon calcitonin (sCT) for oral delivery and evaluate the hypocalcemic effect of biotinylated-sCTs in rats. Biotinylated sCTs was characterized by using ... -
Preparation And In Vitro Evaluation Of Bfgf-Loaded Chitosan Nanoparticles
(Taylor & Francis Inc, 2007)The objective of our study was to prepare and characterize basic fibroblast growth factor (bFGF)-loaded nanoparticles. Protein-loaded chitosan nanoparticles were obtained by ionotropic gelation process based on the interaction ... -
Network On Veterinary Medicines Initiated By The European Federation For Pharmaceutical Sciences
(Wiley, 2018)The European Federation for Pharmaceutical Sciences (EUFEPS) was founded 25 years ago by more than 20 national pharmaceutical societies and faculty members. As a pan-European organization, it brings together pharmaceutical ... -
Ocular Drug, Gene And Cellular Delivery Systems And Advanced Therapy Medicinal Products
(2018)Due to recent advances in science and technology, when the products used in therapy are examined, ophthalmology has a priority in terms of research and development, preclinical and clinical studies of innovative drugs, ... -
Long-Circulating Peg-Pe Micelles Co-Loaded With Paclitaxel And Elacridar (Gg918) Overcome Multidrug Resistance
(Taylor & Francis Ltd, 2012)Overexpression of drug efflux pump P-gp is one of the major reasons to cause multidrug resistance (MDR). To overcome P-gp mediated MDR, modulators, so called P-gp inhibitors, can be used to block efflux pump activity. ... -
High-Performance Liquid Chromatographic Determination Of Amphotericin B In A Liposomal Pharmaceutical Product And Validation Of The Assay
(Preston Publications Inc, 2000)
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