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Browsing Eczacılık Teknolojisi Bölümü by Issue Date 
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Browsing Eczacılık Teknolojisi Bölümü by Issue Date

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    • Estimation Of Aqueous Distributional Spaces In The Dual Perfused Rat Liver 

      Sahin, S; Rowland, M (Cambridge Univ Press, 2000)
      1. The aim of this study was to estimate the aqueous distributional spaces of the liver as a function of the route of input: portal vein (PV) versus hepatic artery (HA). 2. Studies were performed in the in situ single (PV) ...
    • High-Performance Liquid Chromatographic Determination Of Amphotericin B In A Liposomal Pharmaceutical Product And Validation Of The Assay 

      Eldem, T; Arican-Cellat, N (Preston Publications Inc, 2000)
    • Thrombus Localization By Using Streptokinase Containing Vesicular Systems 

      Erdogan, Suna; Oezer, A. Yekta; Volkan, Bilge; Caner, Biray; Bilgili, Hasan (Taylor & Francis Ltd, 2006)
      Our research focused on the preparation of vesicular drug delivery systems, such as liposomes, noisomes, and sphingosomes, for achieving slow release of entrapped proteins in the circulation to increase half-life, to mask ...
    • Development Of A Peptide-Containing Chewing Gum As A Sustained Release Antiplaque Antimicrobial Delivery System 

      Faraj, Jabar A.; Dorati, Rossella; Schoubben, Aurelie; Worthen, David; Selmin, Francesca; Capan, Yilmaz; Leung, Kai; DeLuca, Patrick P. (Springer, 2007)
      The objective of this study was to characterize the stability of KSL-W, an antimicrobial decapeptide shown to inhibit the growth of oral bacterial strains associated with caries development and plaque formation, and its ...
    • Preparation and in Vitro Evaluation Of Bfgf-Loaded Chitosan Nanoparticles 

      Cetin, Meltem; Aktas, Yesim; Vural, Imran; Capan, Yilmaz; Dogan, Lale A.; Duman, Memed; Dalkara, Turgay (Taylor & Francis Inc, 2007)
      The objective of our study was to prepare and characterize basic fibroblast growth factor (bFGF)-loaded nanoparticles. Protein-loaded chitosan nanoparticles were obtained by ionotropic gelation process based on the interaction ...
    • The Operational Multiple Dosing Half-Life: A Key To Defining Drug Accumulation In Patients And To Designing Extended Release Dosage Forms 

      Sahin, Selma; Benet, Leslie Z. (Springer/Plenum Publishers, 2008)
      Half-life (t (1/2)) is the oldest but least well understood pharmacokinetic parameter, because most definitions are related to hypothetical 1-compartment body models that don't describe most drugs in humans. Alternatively, ...
    • Preparation and Characterization of Salmon Calcitonin-Biotin Conjugates 

      Cetin, Meltem; Youn, Yu Seok; Capan, Yilmaz; Lee, Kang Choon (Springer, 2008)
      This study was performed to prepare and characterize the biotinylated Salmon calcitonin (sCT) for oral delivery and evaluate the hypocalcemic effect of biotinylated-sCTs in rats. Biotinylated sCTs was characterized by using ...
    • Stabilite ve Reaksiyon Kinetiği 

      Şumnu, Murat (Hacettepe Üniversitesi, 2009)
      Ülkemizde Türkçe ders kitabı sayısının çok sınırlı olması ve hatta bazı konularda hiç kitap olmaması önemli bir eksikliktir. Öğrencilere ders teksiri verilmesi veya öğrencilerin derslerde not tutmaları yerine, çeşitli ...
    • Parental Preparatlar Teknolojisi 

      Şumnu, Murat (Hacettepe Üniversitesi, 2009)
      Sanayileşme olgusunun en çok değişime uğrattığı mesleklerden biri kuşkusuz eczacılık ve özellikle Farmasötik Teknoloji konulandır. Buna rağmen, ülkemizde yayımlanmış Türkçe ders kitabı sayısının çok sınırlı olmasının büyük ...
    • A Quadruped Study on Chitosan Microspheres Containing Atorvastatin Calcium: Preparation, Characterization, Quantification And In-Vivo Application 

      Eroglu, Hakan; Nemutlu, Emirhan; Turkoglu, Omer Faruk; Nacar, Osman; Bodur, Ebru; Sargon, Mustafa Fevzi; Beskonakli, Etem; Oner, Levent (Pharmaceutical Soc Japan, 2010)
      Atorvastatin is commonly used as a cholesterol lowering agent in patients. Recently, the neuroprotective effects of atorvastatin became the focus of many research studies. In this study, we have formulated chitosan ...
    • Design And Characterization Of Nanocrystal Formulations Containing Ezetimibe 

      Gülsün, Tugba; Gürsoy, Reyhan Neslihan; Öner, Levent (Pharmaceutical Soc Japan, 2011)
      Ezetimibe is a lipid-lowering compound that selectively inhibits the absorption of cholesterol and related phytosterols from the intestine As ezetimibe is almost Insoluble in water, its bioavailability is too low to be ...
    • untranslated

      Kanser Tedavisinde Kullanılacak Aktif Hedeflendirilmiş Farmasötik Nano Taşıyıcılar 

      Sarısözen, Can (Sağlık Bilimleri Enstitüsü, 2012)
      The use of various targeted nanocarriers has turned out to be one of the most important areas of nanomedicine. These carriers are nanosized materials that can carry various drugs and/or imaging agents. It is also possible ...
    • Two Percent Chitosan Mouthwash: A Microbiological And Clinical Comparative Study 

      Uraz, Ahu; Boynuegri, Duygu; Ozcan, Gonen; Karaduman, Burcu; Uc, Dilek; Senel, Sevda; Pehlivan, Selcen; Ogus, Ersin; Sultan, Nedim (Elsevier Taiwan, 2012)
      Background/purpose: The aim of this study was to evaluate the microbiological and clinical effects of a chitosan (CH) mouth rinse on plaque inhibition. Materials and methods: Thirty-six healthy participants were recruited. ...
    • Preparation and In Vitro/In Vivo Evaluation of Microparticle Formulations Containing Meloxicam 

      Eroglu, Hakan; Burul-Bozkurt, Nihan; Uma, Serdar; Oner, Levent (Springer, 2012)
      In this study, we have formulated chitosan-coated sodium alginate microparticles containing meloxicam (MLX) and aimed to investigate the correlation between in vitro release and in vivo absorbed percentages of meloxicam. ...
    • An Overview on Dry Eye Treatment: Approaches for Cyclosporin A Delivery 

      Yavuz, Burçin; Bozdağ Pehlivan, Sibel; Ünlü, Nurşen (2012)
      Dry eye syndrome (DES, Keratoconjunctivitis sicca) is a common disorder of the tear film caused by decreased tear production or increased evaporation. Changes in tear composition also promote inflammation on the ocular ...
    • Long-Circulating Peg-Pe Micelles Co-Loaded with Paclitaxel and Elacridar (Gg918) Overcome Multidrug Resistance 

      Sarisozen, Can; Vural, Imran; Levchenko, Tatyana; Hincal, A. Atilla; Torchilin, Vladimir P. (Taylor & Francis Ltd, 2012)
      Overexpression of drug efflux pump P-gp is one of the major reasons to cause multidrug resistance (MDR). To overcome P-gp mediated MDR, modulators, so called P-gp inhibitors, can be used to block efflux pump activity. ...
    • untranslated

      Hemen Salım Sağlayan Kandesartan Sileksetil Tablet Formülasyonuna Tasarımla Kalite Uygulaması 

      Yüce, Meral (Sağlık Bilimleri Enstitüsü, 2013)
      It was investigated a stable formulation development, process understanding and controlling of immediate release Candesartan Cilexetil 32 mg tablet by using QbD approach. Candesartan Cilexetil is a drug substance ...
    • untranslated

      Barsaklardan Paraselüler Ilaç Absorpsiyonu Üzerine Permeabilite Artırıcı Ajanların Etkisinin Araştırılması 

      Ateş, Müge (Sağlık Bilimleri Enstitüsü, 2013)
      The aim of this study was to investigate the effect of permeability enhancers on paracellular drug absorption. For this purpose, acyclovir classified as Class III drug (high solubility and low permeability) according to ...
    • untranslated

      Paklitaksel Nanopartiküllerinin Kalite Tasarımı Ile Geliştirilmesi ve Değerlendirilmesi 

      Yerlikaya, Fırat (Sağlık Bilimleri Enstitüsü, 2013)
      Quality by design is an FDA initiative that is a science and knowledge-based approach to pharmaceutical development. The aim of this study was to develop and characterize paclitaxel nanoparticles prepared by o/w ...
    • untranslated

      Tıbbi Cihaz Uygulamalarına Bağlı Olarak Gelişen Biyofilm Bazlı Osteomiyelit Tedavisi Için Polimerik Ilaç Taşıyıcı Sistemlerin Formülasyonu Ve Değerlendirilmesi 

      Sarıgöl, Elif (Sağlık Bilimleri Enstitüsü, 2013)
      Medical device is a suitable substrate for bacteria in order to form biofilm which causes a high resistance to used antibiotics and slow or incomplete penetration of antibiotic to infected area, which makes the treatment ...
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