Now showing items 1-20 of 59

    • 18Th European Symposium On Radiopharmacy And Radiopharmaceuticals 

      Radchenko, V.; Engle, J. W.; Roy, C.; Griswold, J.; Nortier, M. F.; Birnbaum, E. R.; Brugh, M.; Mirzadeh, S.; John, K. D.; Fassbender, M. E.; Zhai, Chuangyan; Franssen, Gerben M.; Petrik, Milos; Laverman, Peter; Decristoforo, Clemens; Samia, Ait-Mohand; Véronique, Dumulon-Perreault; Brigitte, Guérin; Summer, D.; Kroess, A.; Rangger, C.; Haas, H.; Laverman, P.; Gerben, F.; von Guggenberg, E.; Decristoforo, C.; Bolzati, Cristina; Salvarese, Nicola; Refosco, Fiorenzo; Meléndez-Alafort, Laura; Carpanese, Debora; Rosato, Antonio; Saviano, Michele; Del Gatto, Annarita; Comegna, Daniela; Zaccaro, Laura; Billaud, Emilie; Ahamed, Muneer; Cleeren, Frederik; Shahbazali, Elnaz; Noël, Tim; Hessel, Volker; Verbruggen, Alfons; Bormans, Guy; Cleeren, F.; Lecina, J.; Koole, M.; Verbruggen, A.; Bormans, G.; Lugatoa, B.; Stucchia, S.; Turollaa, E. A.; Giulianoa, L.; Toddea, S.; Ferraboschib, P.; Klok, R. P.; Mooijer, M. P. J.; Hendrikse, N. H.; Windhorst, A. D.; Collet, C.; Petry, N.; Chrétien, F.; Karcher, G.; Pellegrini-Moïse, N.; Lamandé-Langle, S.; Pfaff, Sarah; Philippe, Cecile; Mitterhauser, Markus; Hacker, Marcus; Wadsak, Wolfgang; Guérard, François; Lee, Yong-Sok; Gouard, Sébastien; Baidoo, Kwamena; Alliot, Cyrille; Chérel, Michel; Brechbiel, Martin W.; Gestin, Jean-François; Lam, K.; Chan, C.; Reilly, R. M.; Paillas, Salomé; Marshall, John; Pouget, Jean-Pierre; Sosabowski, Jane; Briard, Emmanuelle; Auberson, Yves P.; Reilly, John; Healy, Mark; Sykes, David; Paulus, Andreas; Lichtenbelt, Wouter van Marken; Mottaghy, Felix; Bauwens, Matthias; Baranski, Ann-Christin; Schäfer, Martin; Bauder-Wüst, Ulrike; Haberkorn, Uwe; Eder, Matthias; Kopka, Klaus; Chaussard, M.; Hosten, B.; Vignal, N.; Tsoupko-Sitnikov, V.; Hernio, N.; Hontonnou, F.; Merlet, P.; Poyet, J. L.; Sarda-Mantel, L.; Rizzo-Padoin, N.; Cardinale, J.; Schäfer, M.; Benešová, M.; Bauder-Wüst, U.; Seibert, O.; Giesel, F.; Haberkorn, U.; Eder, M.; Kopka, K.; Nematallah, Mansour; Michel, Paquette; Samia, Ait-Mohand; Véronique, Dumulon-Perreault; Roger, Lecomte; Brigitte, Guérin; Fernandez-Maza, L.; Rivera-Marrero, S.; Capote, A. Prats; Parrado-Gallego, A.; Fernandez-Gomez, I.; Balcerzyk, M.; Sablon-Carrazana, M.; Perera-Pintado, A.; Merceron-Martinez, D.; Acosta-Medina, E.; Rodriguez-Tanty, C.; Attili, Bala; Ahamed, Muneer; Bormans, Guy; Philippe, C.; Zeilinger, M.; Scherer, T.; Fürnsinn, C.; Dumanic, M.; Wadsak, W.; Hacker, M.; Mitterhauser, M.; Janssen, B.; Vugts, D. J.; Molenaar, G.T. T.; Funke, U.; Kruijer, P. S.; Dollé, F.; Bormans, G.; Lammertsma, A. A.; Windhorst, A. D.; Vermeulen, Koen; Ahamed, Muneer; Schnekenburger, Michael; Froeyen, Mathy; Olberg, Dag Erlend; Diederich, Marc; Bormansa, Guy; Raaphorst, R. M.; Luurtsema, G.; Lammertsma, A. A.; Elsinga, P. H.; Windhorst, A D.; Rotteveel, Lonneke; Funke, Uta; ten Dijke, Peter; Bogaard, Harm Jan; Lammertsma, Adriaan A.; Windhorst, Albert D.; Song, Lei; Able, Sarah; Falzone, Nadia; Kersemans, Veerle; Vallis, Katherine; Carta, Davide; Salvarese, Nicola; Sihver, Wiebke; Gao, Feng; Pietzsch, Hans Jürgen; Biondi, Barbara; Ruzza, Paolo; Refosco, Fiorenzo; Bolzati, Cristina; Haubner, Roland; Finkensted, Armin; Stegmair, Armin; Rangger, Christine; Decristoforo, Clemens; Zoller, Heinz; Virgolini, Irene J.; Pooters, Ivo; Lotz, Maartje; Wierts, Roel; Mottaghy, Felix; Bauwens, Matthias; Forsback, Sarita; Jörgen, Bergman; Riikka, Kivelä; Karageorgou, M.; Radović, M.; Tsoukalas, C.; Antic, B.; Gazouli, M.; Paravatou-Petsotas, M.; Xanthopouls, S.; Calamiotou, M.; Stamopoulos, D.; Vranješ-Durić, S.; Bouziotis, P.; Lunev, A. S.; Larenkov, A. A.; Petrosova, K. A.; Klementyeva, O. E.; Kodina, G. E.; Kvernenes, O. H.; Adamsen, T. C. H.; Martin, René; Weidlich, Sebastian; Zerges, Anna-Maria; Gameiro, Cristiana; Lazarova, Neva; Müllera, Marco; Luurtsema, Gert; de Vries, Michèl; Ghyoot, Michel; van der Woude, Gina; Zijlma, Rolf; Dierckx, Rudi; Boersma, Hendrikus H.; Elsinga, Philip H.; Lambrecht, Fatma Yurt; Er, Ozge; Ince, Mine; Avci, Cıgır Biray; Gunduz, Cumhur; Sarı, Fatma Aslihan; Ocakoglu, Kasim; Er, Ozge; Ersoz, Onur Alp; Lambrecht, Fatma Yurt; Ince, Mine; Kayabasi, Cagla; Gunduz, Cumhur; Kniess, Torsten; Meister, Sebastian; Fischer, Steffen; Steinbach, Jörg; Ashfaq, Rabia; Iqbal, Saeed; ullah Khan, Irfan; Iglesias-Jerez, R.; Martín-Banderas, L.; Perera-Pintado, A.; Borrego-Dorado, I.; Farinha-Antunes, Ines; Kwizera, Chantal; Lacivita, Enza; Lucente, Ermelinda; Niso, Mauro; De Giorgio, Paola; Perrone, Roberto; Colabufo, Nicola A.; Elsinga, Philip H.; Leopoldo, Marcello; Vaulina, V. V.; Fedorova, O. S.; Orlovskaja, V. V.; Chen, ?�. L.; Li, G. Y.; Meng, F. C.; Liu, R. S.; Wang, H. E.; Krasikova, R. N.; Meléndez-Alafort, Laura; Abozeid, Mohamed; Ferro-Flores, Guillermina; Negri, Anna; Bello, Michele; Uzunov, Nikolay; Paiusco, Martha; Esposito, Juan; Rosato, Antonio; Meléndez-Alafort, Laura; Bolzati, Cristina; Ferro-Flores, Guillermina; Salvarese, Nicola; Carpanese, Debora; Abozeid, Mohamed; Rosato, Antonio; Uzunov, Nikolay; Palmieri, L.; Verbrugghen, T.; Glassner, M.; Hoogenboom, R.; Staelens, S.; Wyffels, L.; Orlovskaja, V. V.; Kuznetsova, O. F.; Fedorova, O. S.; Maleev, V. I.; Belokon, Yu. N.; Geolchanyan, A.; Saghyan, A. S.; Mu, L.; Schibli, R.; Ametamey, S. M.; Krasikova, R. N.; Revunov, Evgeny; Malmquist, Jonas; Johnström, Peter; Van Valkenburgh, Juno; Steele, Dalton; Halldin, Christer; Schou, Magnus; Osati, Samira; Paquette, Michel; Beaudoin, Simon; Ali, Hasrat; Guerin, Brigitte; Leyton, Jeffrey V.; van Lier, Johan E.; Di Iorio, V; Iori, M.; Donati, C.; Lanzetta, V.; Capponi, P. C.; Rubagotti, S.; Dreger, T.; Kunkel, F.; Asti, M.; Zhai, Chuangyan; Rangger, Christine; Summer, Dominik; Haas, Hubertus; Decristoforo, Clemens; Kijprayoon, Suphansa; Ruangma, Ananya; Ngokpol, Suthatip; Tuamputsha, Samart; Filp, Ulrike; Pees, Anna; Taddei, Carlotta; Pekošak, Aleksandra; Gee, Antony D.; Poot, Alex J.; Windhorst, Albert D.; Gunay, Mine Silindir; Ozer, A. Yekta; Erdogan, Suna; Baysal, Ipek; Guilloteau, Denis; Chalon, Sylvie; Galli, Filippo; Artico, Marco; Taurone, Samanta; Bianchi, Enrica; Weintraub, Bruce D.; Skudlinski, Mariusz; Signore, Alberto; Lepareur, Nicolas; Noiret, Nicolas; Hindré, François; Lacœuille, Franck; Benoist, Eric; Garin, Etienne; Trejo-Ballado, F.; Zamora-Romo, E.; Manrique-Arias, J. C.; Gama-Romero, H M; Contreras-Castañon, G.; Tecuapetla-Chantes, R. G.; Avila-Rodriguez, M. A.; Kvaternik, H.; Hausberger, D.; Zink, C.; Rumpf, B.; Aigner, R. M.; Kvaternik, H.; Hausberger, D.; Rumpf, B.; Aigner, R. M.; Janković, Drina; Lakić, Mladen; Savić, Aleksandar; Ristić, Slavica; Nikolić, Nadežda; Vukadinović, Aleksandar; Sabo, Tibor J.; Vranješ-Đurić, Sanja; Vranješ-Đurić, S.; Radović, M.; Janković, D.; Nikolić, N.; Goya, G. F.; Calatayud, P.; Spasojević, V.; Antić, B.; Goblet, David; Gameiro, Cristiana; Lazarova, Neva; Gameiro, Cristiana; Oxley, Ian; Abrunhosa, Antero; Kramer, Vasko; Vosjan, Maria; Spaans, Arnold; Vats, Kusum; Satpati, Drishty; Sarma, Haladhar D.; Banerjee, Sharmila; Wojdowska, W.; Pawlak, D. W.; Parus, L. J.; Garnuszek, P.; Mikołajczak, R.; Pijarowska-Kruszyna, J.; Jaron, A.; Kachniarz, A.; Malkowski, B.; Garnuszek, P.; Mikolajczak, R.; Ilem-Ozdemir, Derya; Caglayan-Orumlu, Oya; Asikoglu, Makbule; Ilem-Ozdemir, Derya; Caglayan-Orumlu, Oya; Asikoglu, Makbule; Eveliina, Arponen; Semi, Helin; Timo, Saarinen; Simo, Vauhkala; Esa, Kokkomäki; Pertti, Lehikoinen; De Simone, Mariarosaria; Pascali, Giancarlo; Carzoli, Ludovica; Quaglierini, Mauro; Telleschi, Mauro; Salvadori, Piero A.; Lam, Phoebe; Aistleitner, Martina; Eichinger, Reinhard; Artner, Christoph; Nakka, Surendra; MC, Hemantha Kumara; Al-Qahtani, Mohammed; Al-Qahtani, Mohammed; Al-Malki, Yousif; Mambilima, N.; Rubow, S. M.; Berroterán-Infante, N.; Hacker, M.; Mitterhauser, M.; Wadsak, W.; Funke, Uta; Cleeren, Frederik; Lecina, Joan; Gallardo, Rodrigo; Verbruggen, Alfons M.; Bormans, Guy; Ramos-Membrive, Rocío; Brotons, Ana; Quincoces, Gemma; Inchaurraga, Laura; de Redín, Inés Luis; Morán, Verónica; García-García, Berta; Irache, Juan Manuel; Peñuelas, Iván; Trabelsi, M.; Cooper, M. S.; Abella, Alejandra; Fuente, Teodomiro; Montellano, Antonio Jesús; Martínez, Teresa; Rabadan, Ruben; Meseguer-Olmo, Luis; Lehtiniemi, P.; Yim, C.; Mikkola, K.; Nuutila, P.; Solin, O.; von Guggenberg, E.; Rangger, C.; Mair, C.; Balogh, L.; Pöstényi, Z.; Pawlak, D.; Mikołajczak, R.; Socan, A.; Peitl, P. Kolenc; Krošelj, M.; Rangger, C.; Decristoforo, C.; Collet, C.; Remy, S.; Didier, R.; Vergote, T.; Karcher, G.; Véran, N.; Pawlak, D.; Maurin, M.; Garnuszek, P.; Karczmarczyk, U.; Mikołajczak, R.; Fredericia, Pil; Severin, Gregory; Groesser, Torsten; Köster, Ulli; Jensen, Mikael; Leonte, R.; Puicea, F. D.; Raicu, A.; Min, E. A.; Serban, R.; Manda, G.; Niculae, D.; Zerna, Marion; Schieferstein, Hanno; Müller, Andre; Berndt, Mathias; Yim, Cheng-Bin; Mikkola, Kirsi; Nuutila, Pirjo; Solin, Olof; Seifert, D.; Ráliš, J.; Lebeda, O.; Selivanova, Svetlana V.; Senta, Helena; Lavallée, Éric; Caouette, Lyne; Turcotte, Éric; Lecomte, Roger; Kochovska, Marina Zdraveska; Ivanovska, Emilija Janjevik; Jokic, Vesna Spasic; Ackova, Darinka Gjorgieva; Smilkov, Katarina; Makreski, Petre; Stafilov, Trajče; Janevik-Ivanovska, Emilija; Alemu, Aschalew; Muchira, Joel Munene; Wanjeh, David Mwanza; Janevik-Ivanovska, Emilija; Janevik-Ivanovska, Emilija; Zdravev, Zoran; Bhonsle, Uday; Alberto, Osso Júnior João; Duatti, Adriano; Angelovska, Bistra; Stojanovska, Zdenka; Sarafinovska, Zorica Arsova; Bosnakovski, Darko; Gorgieva-Ackova, Darinka; Smilkov, Katarina; Drakalska, Elena; Venkatesh, Meera; Gulaboski, Rubin; Colin, Didier J.; Inkster, James A. H.; Germain, Stéphane; Seimbille, Yann (2016)
      OP03 Selective extraction of medically-related radionuclides from proton-irradiated thorium targets, V. Radchenko, J.W. Engle, C. Roy, J. Griswold, M.F. Nortier, E.R. Birnbaum, M. Brugh, S. Mirzadeh, K. D. John, M.E. ...
    • A Quadruped Study On Chitosan Microspheres Containing Atorvastatin Calcium: Preparation, Characterization, Quantification And In-Vivo Application 

      Eroglu, Hakan; Nemutlu, Emirhan; Turkoglu, Omer Faruk; Nacar, Osman; Bodur, Ebru; Sargon, Mustafa Fevzi; Beskonakli, Etem; Oner, Levent (Pharmaceutical Soc Japan, 2010)
      Atorvastatin is commonly used as a cholesterol lowering agent in patients. Recently, the neuroprotective effects of atorvastatin became the focus of many research studies. In this study, we have formulated chitosan ...
    • Ağızda Dağılan Tablet Formülasyonlarının In Vitro Karakterizasyonları ve Permeabiliteleri Üzerine Farklı Yardımcı Maddelerin ve Basım Tekniklerinin Etkisi 

      Uluhan, Özge Didem; Gülsün İnal, Tuğba; Şahin, Selma (Sağlık Bilimleri Enstitüsü, 2019)
      Orally disintegrating tablets are easier and safer to administered in pediatric and geriatrics, patients with difficulty in swallowing and neurological diseases compared with conventional tablets. Orally disintegrating ...
    • Akut Omurilik Travmalarında Kullanılmak Üzere Nöroprotektif İlaç Yüklü Nanopartiküler İlaç Taşıyıcı Sistem Geliştirilmesi 

      Akyürek, Yasemin (Sağlık Bilimleri Enstitüsü, 2015)
      Methyl prednisolone sodium succinate (MPSS) is a very hydrophilic synthetic glucocorticoid. Although it is usually used for its antiinflammatory effects, it is still the only efficacy proven therapeutic agent which is ...
    • An Overview On Dry Eye Treatment: Approaches For Cyclosporin A Delivery 

      Yavuz, Burçin; Bozdağ Pehlivan, Sibel; Ünlü, Nurşen (2012)
      Dry eye syndrome (DES, Keratoconjunctivitis sicca) is a common disorder of the tear film caused by decreased tear production or increased evaporation. Changes in tear composition also promote inflammation on the ocular ...
    • Antibiyotik İçeren Kuru Toz İnhaler Formülasyonu Tasarımı ve Permeabilite Çalışmaları 

      Akdağ Çaylı, Yağmur (Sağlık Bilimleri Enstitüsü, 2017)
      The aim of this thesis is to develope dry powder inhaler formulation with antibiotic and mucolytic combination to use in the treatment of the lung infection in cystic fibrosis disease. For this purpose, in this thesis, ...
    • Barsaklardan Paraselüler Ilaç Absorpsiyonu Üzerine Permeabilite Artırıcı Ajanların Etkisinin Araştırılması 

      Ateş, Müge (Sağlık Bilimleri Enstitüsü, 2013)
      The aim of this study was to investigate the effect of permeability enhancers on paracellular drug absorption. For this purpose, acyclovir classified as Class III drug (high solubility and low permeability) according to ...
    • Characterization Of Protein And Peptide Binding To Nanogels Formed By Differently Charged Chitosan Derivatives 

      Zubareva, Anastasia; Ilyina, Alla; Prokhorov, Aleksander; Kurek, Denis; Efremov, Mikhail; Varlamov, Valery; Senel, Sevda; Ignatyev, Pavel; Svirshchevskaya, ?�lena (2013)
      Chitosan (Chi) is a natural biodegradable cationic polymer with remarkable potency as a vehicle for drug or vaccine delivery. Chi possesses multiple groups, which can be used both for Chi derivatization and for particle ...
    • Comparison Of Dissolution Profiles Of Commercially Available Lamivudine Tablets 

      Ozturk, Naile; Kaynak, Mustafa Sinan; Sahin, Selma (Dissolution Technologies, Inc, 2015)
      The aim of this study was to investigate the influence of dissolution medium on the in vitro release of lamivudine (100 mg) from four commercially available lamivudine tablets (one reference and three generic). Three ...
    • Comparison Of Intestinal Permeability Of Nebivolol Hydrochloride Loaded Solid Lipid Nanoparticles With Commercial Nebivolol Tablet 

      Gökçe, E.H; Kaynak, M.S; Yurdasiper, A; Üstündağ-Okur, N; Şahin, S. (2018)
    • Dendrimeric Systems And Their Applications In Ocular Drug Delivery 

      Yavuz, Burçin; Bozdağ Pehlivan, Sibel; Ünlü, Nurşen (2013)
      Ophthalmic drug delivery is one of the most attractive and challenging research area for pharmaceutical scientists and ophthalmologists. Absorption of an ophthalmic drug in conventional dosage forms is seriously limited ...
    • Design And Characterization Of Nanocrystal Formulations Containing Ezetimibe 

      Gulsun, Tugba; Gursoy, Reyhan Neslihan; Oner, Levent (Pharmaceutical Soc Japan, 2011)
      Ezetimibe is a lipid-lowering compound that selectively inhibits the absorption of cholesterol and related phytosterols from the intestine As ezetimibe is almost Insoluble in water, its bioavailability is too low to be ...
    • Determination Of Regional Intestinal Permeability Of Diclofenac And Metoprolol Using A Newly-Developed And Validated High Performance Liquid Chromatographic Method 

      Kaynak, Mustafa Sinan; Buyuktuncel, Ebru; Caglar, Hatice; Sahin, Selma (Pharmacotherapy Group, 2015)
      Purpose: To develop a simple and rapid reversed-phase high performance liquid chromatographic (HPLC) method with UV detection for the simultaneous determination of diclofenac, metoprolol tartrate, phenol red and propyl ...
    • Development Of A Peptide-Containing Chewing Gum As A Sustained Release Antiplaque Antimicrobial Delivery System 

      Faraj, Jabar A.; Dorati, Rossella; Schoubben, Aurelie; Worthen, David; Selmin, Francesca; Capan, Yilmaz; Leung, Kai; DeLuca, Patrick P. (Springer, 2007)
      The objective of this study was to characterize the stability of KSL-W, an antimicrobial decapeptide shown to inhibit the growth of oral bacterial strains associated with caries development and plaque formation, and its ...
    • Development of Nano-Formulatıons Contaınıng Neuroprotectıve Actıve Ingredıent and Evaluatıon of Effıcıency in Perıpheral Nerve Injury Model 

      Haidar , Mohammad Karim (Sağlık Bilimleri Enstitüsü, 2018-11-13)
      HAIDAR Mohammad Karim, Development of Nano-formulations Containing Neuroprotective Active Ingredient and Evaluation of Efficiency in Peripheral Nerve Injury Model, Hacettepe University Graduate School of Health Sciences, ...
    • Development Of Novel Self-Assembled Polymeric Micelles From Partially Hydrolysed Poly(2-Ethyl-2-Oxazoline)-Co-Pei-B-Pcl Block Copolymer As Non-Viral Vectors For Plasmid Dna In Vitro Transfection 

      Kara, Asli; Ozturk, Naile; Esendagli, Gunes; Ozkose, Umut Ugur; Gulyuz, Sevgi; Yilmaz, Ozgur; Telci, Dilek; Bozkir, Asuman; Vural, Imran (Taylor & Francis Ltd, 2018)
      A new efficient, non-viral gene delivery cationic polymeric micellar system was developed by partial hydrolysis of poly(2-ethyl-2-oxazoline) (PEtOx) with two different hydrolysis percentages of PEtOx (30% and 60%) to reduce ...
    • Development Of Polycationic Amphiphilic Cyclodextrin Nanoparticles For Anticancer Drug Delivery 

      Varan, Gamze; Benito, Juan M; Mellet, Carmen Ortiz; Bilensoy, Erem (2017)
      Background: Paclitaxel is a potent anticancer drug that is effective against a wide spectrum of cancers. To overcome its bioavailability problems arising from very poor aqueous solubility and tendency to recrystallize upon ...
    • Diyabetik Yara Tedavisinde Kullanılmak Üzere Nanopartiküler Statin ve Kök Hücre İçeren Doku İskelelerinin Formülasyonu ve İn Vitro/İn Vivo Değerlendirilmesi 

      ÖRGÜL, Dilara (Sağlık Bilimleri Enstitüsü, 2017)
      Simvastatin has been shown to support wound healing and stem cell treatment efficacy independent of cholesterol-lowering mechanism in recent studies. Under the light of these facts, in order to provide a new treatment approach ...
    • Doksorubisin ve elakridar içeren PLGA/silika hibrit nanopartiküllerin formülasyonu ve meme kanserindeki etkinliğinin değerlendirilmesi 

      Tonbul, Hayrettin (Sağlık Bilimleri Enstitüsü, 2019)
      Although doxorubicin is efficient alone in cancer treatment, its being a substrate of P-glycoprotein (P-gp) limits its effectiveness. Various approaches have been developed to overcome the growing resistance to these drugs. ...
    • Drug Delivery Systems For Imaging And Therapy Of Parkinson'S Disease 

      Gunay, Mine Silindir; Ozer, A. Yekta; Chalon, Sylvie (2016)
      Background: Although a variety of therapeutic approaches are available for the treatment of Parkinson’s disease, challenges limit effective therapy. Among these challenges are delivery of drugs through the blood brain ...