Browsing Temel Eczacılık Bilimleri Bölümü by Title
Now showing items 107-126 of 144
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P-31 Nmr Correlation Maps Of O-18/O-16 Chemical Shift Isotopic Effects For Phosphometabolite Labeling Studies
(Springer, 2011)Intramolecular correlations among the O-18-labels of metabolic oligophosphates, mapped by J-decoupled P-31 NMR 2D chemical shift correlation spectroscopy, impart stringent constraints to the O-18-isotope distributions over ... -
Plasma 8-Isopgf2 Alpha and Serum Melatonin Levels in Patients with Minimal Cognitive Impairment and Alzheimer Disease
(Tubitak Scientific & Technical Research Council Turkey, 2015)Background/aim: F2 alpha-isoprostane is accepted as an oxidative stress indicator and melatonin shows neuroprotective effects by antioxidative and antiamyloidogenic influences. By measuring these in patients diagnosed with ... -
Poly-(L)-Histidine Immobilized Cryogels for Lysozyme Purification
(Sage Publications Inc, 2016)Immobilized metal ion affinity chromatography is one of the methods used for the adsorption of proteins. In this study, poly(glycidyl methacrylate) cryogel discs were prepared by free radical polymerization. The metal ... -
Polyproline Tetramer Organizing Peptides in Fetal Bovine Serum Acetylcholinesterase
(Elsevier Science Bv, 2013)Acetylcholinesterase (AChE) in the serum of fetal cow is a tetramer. The related enzyme, butyrylcholinesterase (BChE), in the sera of humans and horse requires polyproline peptides for assembly into tetramers. Our goal was ... -
Proguanil Metabolism in Relation To S-Mephenytoin Oxidation in A Turkish Population
(Blackwell Science Ltd, 1996)The oxidation of proguanil was studied in 89 unrelated healthy Turkish volunteers after administration of proguanil (single dose, 200 mg, orally). Based on the distribution of the ratio of proguanil to cycloguanil excreted ... -
Raloksifen'in Biyolojik Materyalden ve Farmasötik Preparattan Analizi İçin Gaz Kromatografisi-Kütle Spektrometrisi Yönteminin Geliştirilmesi ve Valide Edilmesi
(Sağlık Bilimleri Enstitüsü, 2012)Raloxifene is selective estrogen modulator (SERM) drug which is used in the treatment of postmenopausal osteoporosis in women and used for doping in men. A new gas chromatography-mass spectrometry (GC-MS) method was developed ... -
Regeneration and Healing of Bone and Cartilage in Type-1 and Type-2 Diabetes: The Effects of Insulin
(Tubitak Scientific & Technical Research Council Turkey, 2016)Increased fragility of long bones and delay in fracture healing in adults as well as skeletal development disorders in children are thought to be associated with endochondral ossification problems. The extracellular matrix ... -
Role of Serotonin in the Regulation of Renal Proximal Tubular Epithelial Cells
(Taylor & Francis Ltd, 2016)In various renal injuries, tissue damage occurs and platelet activation is observed. Recent studies suggest that some factors, such as serotonin, are released into microenvironment upon platelet activation following renal ... -
Rp-Hplc Method Development and Validation for Estimation of Rivaroxaban in Pharmaceutical Dosage Forms
(Univ Sao Paulo, Conjunto Quimicas, 2013)Rivaroxaban, an anti-clotting medication, acts at a crucial point in the blood-clotting process and stops the formation of blood clots. In this study, RP-HPLC method was developed for the determination of rivaroxaban in ... -
Rutin Ameliorates Methotrexate Induced Hepatic Injury in Rats
(Acta Cirurgica Brasileira, 2015)PURPOSE: To investigate the possible protective effect of rutin on methotrexate induced hepatotoxicity in rats. METHODS: Twenty-two rats were divided into three experimental groups; Control-saline, Mtx, Mtx+Rutin. Hepatic ... -
Saliva/Serum Ghrelin, Obestatin and Homocysteine Levels in Patients With Ischaemic Heart Disease
(2017)Background: We aimed to compare ghrelin, obestatin, homocysteine (Hcy), vitamin B12 and folate levels in the serum and saliva of ischaemic heart disease patients. Methods: Serum and saliva were collected from 33 ischaemic ... -
Sedative Effect of Centranthus Longiflorus Ssp Longiflorus in Rats and the Influence of Adrenalectomy on Its Effect
(Pharmaceutical Soc Japan, 2007)Sedative effect of the aqueous extract of Centranthus longiflorus ssp. longiflorus (Cle-1) on intact and adrenalectomized rats was investigated using a thiopental sleeping test to clarify the relationship of this effect ... -
Sefuroksim Aksetil' in Voltametrik Davranışlarının İncelenmesi ve Elektroanalitik Yöntemlerle Farmasötik Preparatlardan Analizi
(Sağlık Bilimleri Enstitüsü, 2015)In this thesis, square wave voltammetric (SWV) methods have been developed for the quantitative determination of cefuroxime axetil (CEFA) from pharmaceutical preparations. Electrochemical reduction and oxidation of the ... -
Sensitive Adsorptive Voltammetric Method for Determination of Bisphenol A by Gold Nanoparticle/Polyvinylpyrrolidone-Modified Pencil Graphite Electrode
(2016)A novel electrochemical sensor gold nanoparticle (AuNP)/polyvinylpyrrolidone (PVP) modified pencil graphite electrode (PGE) was developed for the ultrasensitive determination of Bisphenol A (BPA). The gold nanoparticles ... -
Serotoninin Renal Hasardaki Rolü
(Sağlık Bilimleri Enstitüsü, 2015)In various acute and chronic renal diseases, tissue damage occurs and platelet activation is observed. Recent studies suggest that some factors released from activated platelets may participate in inflammation and fibrosis ... -
Simultaneous Determination of Ezetimibe and Simvastatin in Pharmaceutical Preparations by MEKC
(Preston Publ Inc, 2010) -
Simultaneous Spectrophotometric Determination Of Ezetimibe And Simvastatin In Pharmaceutical Preparations Using Chemometric Techniques
(Soc Brasileira Quimica, 2008)Two spectrophotometric methods are described for the simultaneous determination of ezetimibe (EZE) and simvastatin (SIM) in pharmaceutical preparations. The obtained data was evaluated by using two different chemometric ... -
Solid-Phase Enzyme Modification Via Affinity Chromatography
(Elsevier Science Bv, 2003)In the present study antileukemic enzyme L-asparaginase (ASNase) and catalase (as a model enzyme) were modified in solid-phase with activated polyethylene glycol (PEG,) by using ligand-immobilized affinity column systems ... -
Specimen Rejection In Laboratory Medicine: Necessary For Patient Safety?
(2015)Introduction The emergency laboratory in Hacettepe University Hospitals receives specimens from emergency departments (EDs), inpatient services and intensive care units (ICUs). The samples are accepted according to the ...
