Koroner Arter Hastalarında Beslenme Durumu ile Serum Asimetrik Dimetil Arjinin (ADMA) Düzeyi Arasındaki İlişki
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Serum ADMA level is a factor to determine cardiovascular diseases (CVD). It is hypothesized that individual nutritional status, dietary quality and dietary antioxidant composition may play a role in regulation of serum ADMA levels. This study was conducted to evaluate the relationship between nutritional status, diet quality and some anthropometric measurements and serum ADMA levels in 129 adult volunteers who were referred to Hacettepe University Faculty of Medicine, Cardiology Policlinic to undergoing coronary angiography. General characteristics, 24-hour food recall, nutritional status and diet quality scores (Healthy Eating Index/HEI) were evaluated after physical examination and some biochemical analyzes were performed. 30,2% of individuals were female, 69,8% were male and the average age was 63,0 ±10,0 years. According to body mass index (BMI), 48.8% of individuals were slightly fat and 32.6% were obese and BMI of female subjects were higher than male subjects (p <0.05). According to the Healthy Eating Index (HEI) there was no significant difference between the dietary qualities of male and female subjects (the average of HEI score was 61.3 ± 10.5 / normal diet quality) (p> 0.05). However, it was determined that inadequate total fruit and whole grain consumption and high sodium intake caused reduce diet quality score. Serum ADMA levels were higher in female subjects (1,3 ± 1,0 mol / L) than male subjects (1,2 ± 1,0 mol / L) (p> 0.05). There was negative correlation between serum ADMA level and dietary quality index and linear relationship between serum ADMA level and BMI and anthropometric measurements, but it was not statistically significant (p> 0.05). There is a need for studies showing an association between serum ADMA levels and anthropometric measurements such as BMI and waist circumference which are important risk factors for cardiovascular diseases.