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Sıçanlarda Sisplatin ile Oluşturulan Nörotoksisiteye Melatoninin Etkisi
(Sağlık Bilimleri Enstitüsü, 2021)Bayraktar UA. The Effect of Melatonin on Cisplatin Induced Neurotoxicity in Rats. Hacettepe University, Faculty of Medicine, Thesis in Physiology, Ankara, 2021 Cisplatin (Cis) induced neurotoxicity is thought to be caused ... -
LARİNKS KANSERİ’NDE ANJİYOGENEZ, PROLİFERASYON, HÜCRE ADEZYONU VE İNVAZYONLA İLİŞKİLİ BİYOBELİRTEÇLERİN HASTALIK ÖZELLİKLERİ İLE İLİŞKİSİNİN ARAŞTIRILMASI
(Tıp Fakültesi, 2021)Larynx squamous cell carcinoma (LSCC) is a commonly seen subtype of head and neck cancer. Despite the advances in diagnosis and treatment options through the years, there has been no improvement in the survival rates ... -
Haemophilus influenzae'larda Tiplendirme Yöntemleri ve Önemi
(Sağlık Bilimleri Enstitüsü, 2021)Haemophilus influenzae is a gram-negative, cocobacilli or bacillus bacterium that can cause systemic and invasive infections. Serotyping of H.influenzae can be done conventionally by capsule-specific antisera or ... -
DESMA MUTANT ZEBRA BALIĞI MODELİNDE TEDAVİ AMAÇLI XMU-MP-1 UYGULAMASI
(Sağlık Bilimleri Enstitüsü, 2021)In this thesis, the application of XMU-MP-1 drug candidate molecule which is a MST1 / 2 kinase inhibitor and selectively inhibits the Hippo pathway was performed by mixing the drug with zebrafish embryo egg water or adult ... -
ÇUBUK İLÇESİ’NDEKİ DEVLET OKULLARINDA 2018-2019 EĞİTİM ÖĞRETİM YILINDA ÖĞRENİM GÖREN 4. SINIF ÖĞRENCİLERİNDE FLORÜRLÜ VERNİK UYGULAMA SIKLIĞI VE EBEVEYNLERİNİN AĞIZ DİŞ SAĞLIĞI BİLGİ VE UYGULAMALARI
(Sağlık Bilimleri Enstitüsü, 2021-03)Kara M. The Prevalance of Fluoride Varnish Application Among the 4th Grade Students in Public Schools of Çubuk District during 2018-2019 Academic Year and their Parents' Knowledge and Practice Concerning Oral and Dental ... -
İŞYERİ SAĞLIK PERSONELİ DERNEĞİ ÜYELERİNİN ÇALIŞMA KOŞULLARININ DEĞERLENDİRİLMESİ
(Sağlık Bilimleri Enstitüsü, 2021-02)Oruç, S., Evaluation of the Working Conditions of the Workplace Health Staff Association Members, Hacettepe University Graduate School of Health Sciences Occupational Health Master Thesis, Ankara, 2021. Workplace nurses ... -
DİYABET HASTALARINDA MİNERAL TRİOKSİT AGREGAT/1α,25-DİHİDROKSİVİTAMİN D3 KOMBİNASYONU İLE DENTAL PULPA KÖK HÜCRELERİNDE ODONTOJENİK FARKLILAŞMANIN ARAŞTIRILMASI
(Sağlık Bilimleri Enstitüsü, 2021-01-15)Dental treatments in diabetic patients have been reported to fail in the long term and these patients have more tooth extraction. It is aimed to investigate the odonto/osteogenic differentiation potential of the combination ... -
Parkinson Hastalığı Hücresel Modelinde İnflamasyonun ve İnflamasyon Sonrası Uygulanan N-Asetilsisteinin H4 Hücrelerindeki Lag3 ve Tlr2 Reseptörleri Üzerine Etkisi
(Sağlık Bilimleri Enstitüsü, 2021)Kaya, Z.B., The Effect of Inflammation and Post-Inflammatory Administration of N-Acetylcysteine on LAG3 and TLR2 Receptors on H4 Cells in the Cellular (In Vitro) Model of Parkinson's Disease, Hacettepe University Graduate ... -
Antioksidan Kullanımının Meme Kanseri Tedavisi Üzerindeki Etkilerinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2021-01-20)Drug resistance against chemotherapy is one of the main factors limitating the success of cancer treatment. Several studies have reported that the expression level of the glutathione S-transferase P1 (GSTP1) isozyme from ... -
İnsan Serum Bütirilkolinesterazının Olası Lipolitik Aktivitesi-Lipid Metabolizması ile İlişkisi.
(Sağlık Bilimleri Enstitüsü, 2021-01-21)Cholinesterases (AChE and BChE) terminate acetylcholine-induced neurotransmission at cholinergic synapses in muscle-nerve junctions. We previously showed BChE expression is regulated by essential fatty acids. The similarity ... -
Investigation of the Role of LAP1B in Transcriptional Regulation of Muscle Cells
(Sağlık Bilimleri Enstitüsü, 2021-01-20)The loss-of-function of the inner nuclear membrane protein LAP1B (lamina-associated polypeptide 1, isoform B) causes muscular dystrophy and cardiomyopathy in humans. The function of LAP1B in muscle is still unknown. The ... -
MOLECULAR PROPERTIES OF CRAYFISH POTASSIUM CHANNELS
(Sağlık Bilimleri Enstitüsü, 2021)Ergin, B., Molecular Properties of Crayfish Potassium Channels. Hacettepe University Graduate School of Health Sciences, Ph.D. Thesis in Biophysics, Ankara, 2021. Potassium channel family is the largest group in the ion ... -
İlaç Yeniden Konumlandırma Yaklaşımı ile Alfa Tübülin Asetilasyonunu Arttırabilecek Bileşiklerin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2020)Drug repurposing approach is used to identify new indications of drugs outside the scope of their original indications. This approach has been used to identify effective compounds for neurodegenerative diseases. Axonal ... -
Müfredat-I Tıbbı̇ye (1290/Hı̇crı̇) Adlı Yazma Eserde Geçen Bazı Bı̇tkı̇Lerı̇n Tıp Tarı̇hı̇ Açısından Değerlendı̇rilmesı̇
(Sağlık Bilimleri Enstitüsü, 2020)The work titled “Müfredat-ı Tıbbiye” consists of lecturers written by Veterinarian İsmail Hilmi Bey. The only known copy is in the Koyunoğlu Museum. The date of writing is specified as 1290 Arabi by İsmail Hilmi Bey's ... -
Çocuk Yanık Yoğun Bakım Ünitesi Yatak Başı Klinik Ekip Vizitlerinde Çocuk Cerrahi Asistanlarının Vizit Yönetim Becerilerinin Değerlendirilmesi ve Klinik Vizit Sürecinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2020-09)The research was carried out in a mixed design in order to examine the process of (clinical) pediatric surgical physician visits performed in the Pediatric Burn Intensive Care Unit and to evaluate the bedside round management ... -
AEBP1/ACLP'nin Protein Etklileşim Ağının Proteomik ve Biyoinformatik Yöntemlerle Araştırılması
(Sağlık Bilimleri Enstitüsü, 2020)Extracellular Matrix (ECM) is the mechanical supportive structure for cells and tissues. Chronic damage may cause loss of ECM integrity that may result in fibrosis which is the progressive and irreversible accumulation of ... -
Spinal Müsküler Atrofi Hastalarının Fibroblast Kültürlerinde Mikrotübül Stabilitesinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2020)Spinal muscular atrophy (SMA), which is characterized by motor neuron loss and muscle atrophy, is a neurodegenerative disease primarily in childhood. In SMA, Survival of motor neuron 1 (SMN1) gene mutations lead to the ... -
Mikrodizi Gen İfade Verilerinde Farklı Öznitelik Seçim Yöntemleri ile Sınıflama Yöntemlerinin Performanslarının Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2020-08-07)Bioinformatics is an interdisciplinary branch of science that combines statistics, biology, computing, mathematics, and genetics, and thanks to the analysis in bioinformatics, it can be shown which abnormalities causes ... -
Determination of Lipid Metabolism Alterations and Their Association with Disease Pathogenesis in Sickle Cell Disease
(Sağlık Bilimleri Enstitüsü, 2020-07-07)Sickle cell disease (SCD) is a hemoglobinopathy that causes severe anemia and is characterized by lipid abnormalities, oxidative stress and chronic inflammation. It is caused by a single point-mutation in the beta globin ... -
Bisfenol A’nın Hepg2 Hücrelerine Olan Etkilerinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2020)Öz, E. Examination of the Effects of Bisphenol A on HepG2 Cells. Hacettepe University Graduate School of Health Sciences, Biochemistry Program, Master Thesis, Ankara, 2020. In this study, it was aimed to determine the ...
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