Nanoteknoloji ve Nanotıp Bölümü Tez Koleksiyonu
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Mimetik Biyomoleküller Kullanılarak Metamalzeme Yüzeyinin Geliştirilmesi ve Meta-Biyo-Sensör Hazırlanması
(Fen Bilimleri Enstitüsü, 2019)In the scope of this thesis, the potential use of metamaterials, which have outstanding features at nano scales as an efficient transducer was presented. For this purpose, two different metamaterials such as Split Ring ... -
Partikül Bazlı Sıvı Kromatografisi Kolonlarında Transport Modellerinin Kaşılaştırmalı Olarak İncelenmesi
(Fen Bilimleri Enstitüsü, 2019-06-17)Within the scope of the thesis, the Ideal Model (IM), Equilibrium Dispersive Model (EDM) and Random Walk Model (RWM) which are used in the literature as transport models for high performance liquid chromatography (HPLC) ... -
İntratümöral Uygulamaya Yönelik Nanolipozom Formülasyonlarının Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2019)Purpose of our thesis; it has been aimed to prepare injectable formulations of the chemotherapeutic agent, which is effective in cancer cells, into nanoliposomes and to develop an intratumorally effective treatment approach. ... -
Nükleotid Saflaştırılması İçin Baskılanmış Manyetik Poli(Hidroksietil Metakrilat) (Mphema) Nanoküreler
(Fen Bilimleri Enstitüsü, 2019)Nucleotides and nucleosides participate in other metabolic functions because they are part of the biosynthetic pathways and play an important role as biological regulators. Nucleotides in various forms play an important ... -
Bazı Non-Steroidal Anti-İnflamatuar İlaçların Yeni Türevlerinin Sentezi ve Bunların Nanosistemler ile Değerlendirilmesi
(Fen Bilimleri Enstitüsü, 2019)NSAIDs, such as acetylsalicylic acid, ibuprofen, naproxen and flurbiprofen, are commonly used commercial drugs with weakly acidic structure. These types of drugs are well absorbed from the stomach and bowel mucosa. Treating ... -
Escherichia Coli ve Salmonella Enteritidis Tayinine Yönelik Yatay Akış Analiz Sistemi Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2019)In recent years, rapid and accurate detection of pathogenic bacteria has been a current research area in terms of public health and food safety. One of the effective methods for this purpose is Surface-enhanced Raman ... -
Siklodekstrin Nanopartiküllerinin HEPG-2 Karaciğer Kanseri Hücre Hattı Üzerine Etkisinin Proteomik Çalışmalarla İncelenmesi
(Fen Bilimleri Enstitüsü, 2019)Proteome; derived from the combination of protein and genome words, is a word that covers all the proteins encoded by a particular genome. Proteome analysis is called proteomics. An organism has different protein expressions ... -
Elektrokaplama Yöntemi ile Elde Edilen Metal Oksitlerin Memristif ve Yapısal Özellikleri
(Fen Bilimleri Enstitüsü, 2019-09-30)As one of the most promising memory devices, memristor has the advantages of high-density data storage, low power consumption, faster operation and non-volatility over the conventional architectures. Having the potential ... -
Synthesis of Functionalized Magnetite (Fe3o4) Nanoparticles and Targeting to the Tumour Cell (Hela) For Cancer Diagnosis and Treatment
(Fen Bilimleri Enstitüsü, 2019-07-02)Cancer is one of the global problems of this century and responsible for the death of one in 8 men and one in 11 women worldwide today. By 2040, 29.5 million new cancer cases are estimated to occur by the International ... -
Nanomodifiyeli Kardiyopleji Solüsyonunun Miyokard Korunmasındaki Etkisinin Gözlenmesi
(Fen Bilimleri Enstitüsü, 2019)In this thesis study, the effects of cardioplegia solutions modified with Poly(2-hydroxyethyl methacrylate) (PHEMA) and Poly(2-hydroxyethyl methacrylate) - N-methacryloyl-L-histidine methyl ester (PHEMAH) nanoparticles on ... -
İçi Boşluklu Gözenekli Silika Nanopartiküllerin İlaç Taşıyıcı Sistem Olarak Hazırlanması ve İncelenmesi
(Fen Bilimleri Enstitüsü, 2019)In this thesis, designing a drug delivery system with high drug loading capacity due to it’s hollow interior, effective drug delivery by endosomal escape with proton-sponge effect and elongated blood circulation time to ... -
Organik Modifiye Montmorilonit (ORG-MMT) ve Gümüş İçeren Fonksiyonel Anhidrit Kopolimer-Kil Nanokompozitlerin Hazırlanması ve Biyolojik Aktivitelerinin Belirlenmesi
(Fen Bilimleri Enstitüsü, 2019)Nanotechnology and nanomaterials have become a central of scientific studies. Today, it is very important develop functional structures that provide various need and solve problems in the area of biotechnology, medicine, ... -
L-Karnitin Yüklü Polimerik ve Lipit Bazlı Nanopartiküler Sistemlerin Hazırlanması ve İn-Vitro Değerlendirilmesi
(Fen Bilimleri Enstitüsü, 2019-06-10)L-carnitine has attracted attention in the treatment of important problems of era such as obesity, diabetes and regional slimming in recent years due to its metabolic effects that increase fat loss and muscle building in ... -
Nanobio-Approaches For The Detection Of Bacteria By Sers
(Fen Bilimleri Enstitüsü, 2019)The main objective of this PhD thesis is to develop nanobio-based detection/identification protocols for pathogenic bacteria. Escherichia coli (E.coli) was the main target bacteria, Staphylococcus aureus (S.aureus) and ... -
The Role Of Glutathione-S-Transferase In Epithelial Mesenchymal Transition (Emt) Model In Colorectal Cancer And The Enhancement Of Adjuvant Therapy By Targeting Glutathione-S-Transferase Inhibitor
(Fen Bilimleri Enstitüsü, 2019)Colorectal cancer is the third leading cause of cancer-related deaths worldwide. For colorectal cancers that have not spread to distant sites, surgery is usually the primary or first treatment option. However, chemotherapy ... -
Kemik Dokusunun Rejenerasyonunda Hücre Tabakalarının Farklı Uygulamaları
(Fen Bilimleri Enstitüsü, 2018)This study was supported by Hacettepe University Scientific Research Projects Coordination Unit (Project Number: 17055) and Ülkü Bozoğlu was also supported by TÜBİTAK (TÜBİTAK-2211-A). Within the scope of the presented ... -
Arsenik Baskılanmış Manyetik Nanopartiküllerin Üretimi
(Fen Bilimleri Enstitüsü, 2018-08-14)Arsenic (As) (atomic number 33) has a single stable isotope with 74.9 relative mass units in the environment. Arsenic has 4 oxidation states with -3, 0, +3 and +5. In general, inorganic arsenic compounds are more toxic ... -
Farklı Nanopartiküller Kullanılarak Bakteri Tayinine Yönelik Gradient Yöntemi Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2018-09-06)Nowadays, development of label-free, easy handling, cost-effective and fast responsive analysis methods have gained great importance. In this study, it was aimed to develop an easy handling and cost-effective nanoparticle ... -
GaN İnce Filmlerin Esr Spektroskopisi İle İncelenmesi
(Fen Bilimleri Enstitüsü, 2018)In this thesis; it is aimed to characterize GaN sample which has been widely used nowadays, especially in electronics sector. GaN epitaxial structures have been produced with different contents of carbon dopants by ... -
Prostat Kanseri Biyobelirteçlerinin Tayini İçin Nanoplazmonik Platformların Hassasiyetinin Arttırılması
(Fen Bilimleri Enstitüsü, 2018-06)ABSTRACT ENHANCING THE SENSITIVITY OF NANOPLASMONIC PLATFORMS FOR DETECTING PROSTATE CANCER BIOMARKERS Semih ÇALAMAK Doctor of Philosophy, Department of Nanotechnology and Nanomedicine Supervisor: Prof. Dr. Kezban ...
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