Nanoteknoloji ve Nanotıp Bölümü Tez Koleksiyonu
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Donepezil Yüklü Nanopartiküler İlaç Taşıyıcı Sistemlerin Hazırlanması ve In Vitro Değerlendirilmesi
(Fen Bilimleri Enstitüsü, 2018)There are about 46 million dementia worldwide today. The cause of disease is unknown and there is currently no treatment to stop or slow the degenerative process.1 However, there are some symptomatic treatment approaches ... -
Hıgh Performance Mıoc (Multıfunctıonal Integrated Optıcal Chıp) Desıgn Fabrıcatıon And Characterızatıon For Fıber Optıc Gyroscope Applıcatıons
(Fen Bilimleri Enstitüsü, 2022)Laser-based fiber optic gyrometers (FOG) used in navigation systems have been developed for various applications since the 1970s. In this thesis, the working principle of FOG and the sub-components of the system are ... -
Gan Tabanlı Güç Aygıtları İçin Pasivasyon Tabakası Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2022)In this study, various passivation layers are developed and characterized for gallium nitride (GaN) transistors used in power electronics applications. Dielectric properties of the passivation material on high breakdown ... -
Odaklanmış İyon Işını İle Memristor Üretim Süreci Geliştirme ve Elektriksel Karakterizasyonu
(Fen Bilimleri Enstitüsü, 2022-01)The transistor element, which is one of the most important building blocks of electronics, has provided the realization of many digital logic circuits and memory applications. However, due to the fact that the transistors ... -
MnB Yumuşak Manyetik İnce Filmlerin Sentezi ve Karakteriasyonu
(Fen Bilimleri Enstitüsü, 2021)In this study, manganese monoboride (MnB) thin films with soft ferromagnetic properties are fabricated by magnetron sputtering technique. Thin films are grown via two different techniques; co-sputtering and multilayer ... -
Preparation and Characterization of Starch Nanoparticles for Delivery of Histone Deacetylase Inhibitor CG-1521 in Breast Cancer Treatment
(Fen Bilimleri Enstitüsü, 2021)Starch nanoparticles offer many possibilities in drug delivery systems due to their biocompatibility and appropriate physicochemical properties. Sufficient systems have not yet been designed to deliver histone deacetylase ... -
Yüksek Güç Uygulamaları İçin Galyum Nitrür Temelli Yüksek Elektron Hareketlilikli Transistör Tasarımı, Fabrikasyonu ve Karakterizasyonu
(Fen Bilimleri Enstitüsü, 2020)In this study, novel epitaxial structures for high power applications have been grown by using Metal-Organic Chemical Vapour Deposition (MOCVD) technique. Photoluminescence (PL), Atomic Force Microscopy (AFM), X-Ray ... -
Sıcaklık ile Ayarlanabilir Vanadyum Oksit Temelli Nanofotonik Yapılar
(Fen Bilimleri Enstitüsü, 2020-09)In this work, the phase change behavior of vanadium dioxide (VO2) thin films grown by RF magnetron sputtering and post annealing process, has been studied by its optical and electrical parameters. The structures of thin ... -
Mimetik Biyomoleküller Kullanılarak Metamalzeme Yüzeyinin Geliştirilmesi ve Meta-Biyo-Sensör Hazırlanması
(Fen Bilimleri Enstitüsü, 2019)In the scope of this thesis, the potential use of metamaterials, which have outstanding features at nano scales as an efficient transducer was presented. For this purpose, two different metamaterials such as Split Ring ... -
Partikül Bazlı Sıvı Kromatografisi Kolonlarında Transport Modellerinin Kaşılaştırmalı Olarak İncelenmesi
(Fen Bilimleri Enstitüsü, 2019-06-17)Within the scope of the thesis, the Ideal Model (IM), Equilibrium Dispersive Model (EDM) and Random Walk Model (RWM) which are used in the literature as transport models for high performance liquid chromatography (HPLC) ... -
İntratümöral Uygulamaya Yönelik Nanolipozom Formülasyonlarının Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2019)Purpose of our thesis; it has been aimed to prepare injectable formulations of the chemotherapeutic agent, which is effective in cancer cells, into nanoliposomes and to develop an intratumorally effective treatment approach. ... -
Nükleotid Saflaştırılması İçin Baskılanmış Manyetik Poli(Hidroksietil Metakrilat) (Mphema) Nanoküreler
(Fen Bilimleri Enstitüsü, 2019)Nucleotides and nucleosides participate in other metabolic functions because they are part of the biosynthetic pathways and play an important role as biological regulators. Nucleotides in various forms play an important ... -
Bazı Non-Steroidal Anti-İnflamatuar İlaçların Yeni Türevlerinin Sentezi ve Bunların Nanosistemler ile Değerlendirilmesi
(Fen Bilimleri Enstitüsü, 2019)NSAIDs, such as acetylsalicylic acid, ibuprofen, naproxen and flurbiprofen, are commonly used commercial drugs with weakly acidic structure. These types of drugs are well absorbed from the stomach and bowel mucosa. Treating ... -
Escherichia Coli ve Salmonella Enteritidis Tayinine Yönelik Yatay Akış Analiz Sistemi Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2019)In recent years, rapid and accurate detection of pathogenic bacteria has been a current research area in terms of public health and food safety. One of the effective methods for this purpose is Surface-enhanced Raman ... -
Siklodekstrin Nanopartiküllerinin HEPG-2 Karaciğer Kanseri Hücre Hattı Üzerine Etkisinin Proteomik Çalışmalarla İncelenmesi
(Fen Bilimleri Enstitüsü, 2019)Proteome; derived from the combination of protein and genome words, is a word that covers all the proteins encoded by a particular genome. Proteome analysis is called proteomics. An organism has different protein expressions ... -
Elektrokaplama Yöntemi ile Elde Edilen Metal Oksitlerin Memristif ve Yapısal Özellikleri
(Fen Bilimleri Enstitüsü, 2019-09-30)As one of the most promising memory devices, memristor has the advantages of high-density data storage, low power consumption, faster operation and non-volatility over the conventional architectures. Having the potential ... -
Synthesis of Functionalized Magnetite (Fe3o4) Nanoparticles and Targeting to the Tumour Cell (Hela) For Cancer Diagnosis and Treatment
(Fen Bilimleri Enstitüsü, 2019-07-02)Cancer is one of the global problems of this century and responsible for the death of one in 8 men and one in 11 women worldwide today. By 2040, 29.5 million new cancer cases are estimated to occur by the International ... -
Nanomodifiyeli Kardiyopleji Solüsyonunun Miyokard Korunmasındaki Etkisinin Gözlenmesi
(Fen Bilimleri Enstitüsü, 2019)In this thesis study, the effects of cardioplegia solutions modified with Poly(2-hydroxyethyl methacrylate) (PHEMA) and Poly(2-hydroxyethyl methacrylate) - N-methacryloyl-L-histidine methyl ester (PHEMAH) nanoparticles on ... -
İçi Boşluklu Gözenekli Silika Nanopartiküllerin İlaç Taşıyıcı Sistem Olarak Hazırlanması ve İncelenmesi
(Fen Bilimleri Enstitüsü, 2019)In this thesis, designing a drug delivery system with high drug loading capacity due to it’s hollow interior, effective drug delivery by endosomal escape with proton-sponge effect and elongated blood circulation time to ... -
Organik Modifiye Montmorilonit (ORG-MMT) ve Gümüş İçeren Fonksiyonel Anhidrit Kopolimer-Kil Nanokompozitlerin Hazırlanması ve Biyolojik Aktivitelerinin Belirlenmesi
(Fen Bilimleri Enstitüsü, 2019)Nanotechnology and nanomaterials have become a central of scientific studies. Today, it is very important develop functional structures that provide various need and solve problems in the area of biotechnology, medicine, ...
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