Nanoteknoloji ve Nanotıp Bölümü Tez Koleksiyonu
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NANOBIO-APPROACHES FOR THE DETECTION OF BACTERIA BY SERS
(Fen Bilimleri Enstitüsü, 2019)The main objective of this PhD thesis is to develop nanobio-based detection/identification protocols for pathogenic bacteria. Escherichia coli (E.coli) was the main target bacteria, Staphylococcus aureus (S.aureus) and ... -
The Role of Glutathione-S-Transferase in Epithelial Mesenchymal Transition (EMT) Model in Colorectal Cancer and the Enhancement of Adjuvant Therapy by Targeting Glutathione-S-Transferase Inhibitor
(Fen Bilimleri Enstitüsü, 2019)Colorectal cancer is the third leading cause of cancer-related deaths worldwide. For colorectal cancers that have not spread to distant sites, surgery is usually the primary or first treatment option. However, chemotherapy ... -
Kemik Dokusunun Rejenerasyonunda Hücre Tabakalarının Farklı Uygulamaları
(Fen Bilimleri Enstitüsü, 2019-01)This study was supported by Hacettepe University Scientific Research Projects Coordination Unit (Project Number: 17055) and Ülkü Bozoğlu was also supported by TÜBİTAK (TÜBİTAK-2211-A). Within the scope of the presented ... -
Arsenik Baskılanmış Manyetik Nanopartiküllerin Üretimi
(Fen Bilimleri Enstitüsü, 2018-08-14)Arsenic (As) (atomic number 33) has a single stable isotope with 74.9 relative mass units in the environment. Arsenic has 4 oxidation states with -3, 0, +3 and +5. In general, inorganic arsenic compounds are more toxic ... -
Farklı Nanopartiküller Kullanılarak Bakteri Tayinine Yönelik Gradient Yöntemi Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2018-09-06)Nowadays, development of label-free, easy handling, cost-effective and fast responsive analysis methods have gained great importance. In this study, it was aimed to develop an easy handling and cost-effective nanoparticle ... -
GaN İnce Filmlerin Esr Spektroskopisi İle İncelenmesi
(Fen Bilimleri Enstitüsü, 2018)In this thesis; it is aimed to characterize GaN sample which has been widely used nowadays, especially in electronics sector. GaN epitaxial structures have been produced with different contents of carbon dopants by ... -
Prostat Kanseri Biyobelirteçlerinin Tayini İçin Nanoplazmonik Platformların Hassasiyetinin Arttırılması
(Fen Bilimleri Enstitüsü, 2018-06)ABSTRACT ENHANCING THE SENSITIVITY OF NANOPLASMONIC PLATFORMS FOR DETECTING PROSTATE CANCER BIOMARKERS Semih ÇALAMAK Doctor of Philosophy, Department of Nanotechnology and Nanomedicine Supervisor: Prof. Dr. Kezban ... -
Elektrokimyasal Yöntemle Grafen Nanoşerit Esaslı Cam Fiber-Karbon Platform Üzerinde Triklosan Tayini
(Fen Bilimleri Enstitüsü, 2018)Carbon materials have an extensive usage on many areas of utilization, like healthcare, textile, and electronics, due to unique characteristic features of carbon. Coal tar accepted as primer material by the reasons of ... -
Raman Sinyalinin Güçlendirilmesine Yönelik Nanoyapılı Sensör Yüzeyinin Hazırlanması
(Fen Bilimleri Enstitüsü, 2018)Raman spectroscopy is a fast and highly sensitive analysis method which provides information about molecular structure. However, Raman scattering is an extremely weak process. Therefore, the Raman signal intensity should ... -
Glukozamin (Ga) Bağlı Hyaluronik Asit (Ha) Nanopartiküllerin (Ga-Nha) Geliştirilerek Yapısal Özelliklerinin Belirlenmesi Ve In Vıtro Hücre Kültüründeki Etkilerinin Araştırılması
(Fen Bilimleri Enstitüsü, 2018)Osteoarthritis (OA) is a articular joint disease which causes pain, limitation of movement, deformity and can lead to disability and mortality. Glucosamine (GA) and chondroitin sulfate (CS) are alter the course of the ... -
Nanoboyutlu Polimerik Miseller Sistemler İle Gen Tedavisine Yönelik Yaklaşımlar
(Fen Bilimleri Enstitüsü, 2018)Gene therapy is an effective treatment method that has received considerable attention recently in the treatment of many genetic diseases. The success of gene therapy depends on the development of an efficient carrier ... -
Kompozit Formda Monodispers Gözenekli Mikrokürelerin Sentezi Ve Boya Duyarlı Güneş Hücrelerinde Kullanımı
(Fen Bilimleri Enstitüsü, 2018-09)In this thesis, the conversion efficiency of dye sensitized solar cells were investigated. A multi-stage hydrolysis-condensation method was developed for synthesizing metal oxides and their composites in the form of ... -
İlaç Taşıyıcı Sistem Olarak Kullanılmak Üzere Kil-Protein Kompozit Nanopartiküllerin Hazırlanması Ve Karakterizasyonu
(Fen Bilimleri Enstitüsü, 2018-05)Controlled release systems have advantages compared to conventional methods, including reduced toxicity, increased efficiency, patient compliance and comfort. Biodegradable polymers are strongly recommended as an active ... -
KANSER TEDAVİSİNDE KULLANILMAK ÜZERE İPEK PROTEİN NANOPARTİKÜLLERİN HAZIRLANMASI VE KARAKTERİZASYONU
(Fen Bilimleri Enstitüsü, 2018-02)For the treatment of cancer in recent years, new generation methods are being developed by directly targeting of cancer cells, thereby preventing damage to healthy tissue. siRNA therapies are one of the new generation ... -
Using Of Nanofiber Based Electrodes For Detection Of Organic Molecules
(Fen Bilimleri Enstitüsü, 2018)The disposable electrodes of the diabetes sensors used in our country are in the case of external dependency due to the necessity of importation. In addition, these types of electrodes are only capable of measuring the ... -
Siklodekstrin Nanopartiküllerin Sitotoksik Etki Mekanizmasının Aydınlatılmasında Biyoenformatik Yaklaşımlar
(Fen Bilimleri Enstitüsü, 2018)This thesis aims to determine the cytotoxic effect of previously manufactured cyclodextrin nanoparticles on cancer cells by metabolomic studies with different bioinformatic approaches. MDA-MB-231 breast cancer cell lines ... -
FABRICATION AND CHARACTERIZATION OF NOVEL POLYMER/ORGANO-MMT (ORGANO-SILICA)/BIOPOLYMER NANOCOMPOSITE BLENDS BY REACTIVE EXTRUSION
(Fen Bilimleri Enstitüsü, 2018-01-23)ABSTRACT FABRICATION AND CHARACTERIZATION OF NOVEL POLYMER/ORGANO-MMT (ORGANO-SILICA)/BIOPOLYMER NANOCOMPOSITE BLENDS BY REACTIVE EXTRUSION Bayram Ali GÖÇMEN Doctor of Philosophy, Department of Nanotechnology ... -
YENİ NESİL FONKSİYONEL KOPOLİMER-RAFT AJAN/ORGANO-SİLİKAT NANOYAPILARININ SENTEZİ VE KARAKTERİZASYONU
(Fen Bilimleri Enstitüsü, 2017)This thesis presents a new approach for the synthesis of polymer nanostructures using a bifunctional reversible addition-fragmentation chain transfer (RAFT) agent, two types of modified organo-montmorillonites, such as a ... -
İKİ AŞAMALI TOTAL EKLEM PROTEZİ AMELİYATLARI İÇİN ANTİBİYOTİK YÜKLÜ BOŞLUK DOLDURUCULARIN GELİŞTİRİLMESİ
(Fen Bilimleri Enstitüsü, 2018-01)Nanotechnological materials and the use of these materials are increasing in all areas as well as biomedical and medicine field. With decreasing the size of material up to nano scales and designing of them, the new ideas ... -
POLİKATYONİK AMFİFİLİK SİKLODEKSTRİN NANOPARTİKÜLLERİN ANTİKANSER İLAÇ TAŞIYICI SİSTEM OLARAK ETKİNLİK VE GÜVENLİK AÇISINDAN DEĞERLENDİRİLMESİ
(Fen Bilimleri Enstitüsü, 2018-01-10)Nanoparticulate drug delivery systems possess advantages in cancer treatment due to their physicochemical properties. Several polymers have been used to prepare nanoparticles. Cyclodextrins, are natural oligosaccharides. ...
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