• CXCL KEMOKİN ÖNCÜL DİZELERİNDEN TÜREVLENEN KÜÇÜK PEPTİT MOLEKÜLLERİNİN İMMÜN DÜZENLEYİCİ ETKİSİNİN DEĞERLENDİRİLMESİ 

  Yöyen Ermiş, Diğdem (Kanser Enstitüsü, 2019-03-12)

  Peptide structured small molecules function in the regulation of a variety of physiological processes and intercellular communication. In this study, precursor sequences of known 17 CXCL chemokine molecules were analyzed ...
• Kolorektal Kanserlerde Th17 İlişkili IL-17, IL-21 ve IL-22 Sitokinlerinin Ekspresyon Düzeylerinin Belirlenmesi 

  İbrahimli, Nurlana (Sağlık Bilimleri Enstitüsü, 2019)

  Immune system cells and released cytokines in tumor microenvironment have a very important role in cancer prognosis. Also, T-helper 17 (Th17) cells have been frequently found in many tumors microenvironment and their effects ...
• CyberKnife® Robotik Radyocerrahi Cihazında MAGIC Polimer Jel Dozimetre İle Küçük Alan Dozimetrisinin İncelenmesi 

  ENKAVİ, Mehmet Fazıl (Kanser Enstitüsü, 2018)

  ENKAVİ, M.F. Investigation of Small Field Dosimetry with MAGIC Polymer Gel Dosimeter in CyberKnife® Robotic Radiosurgery Device. Hacettepe University Institute of Health Sciences, MSc. Thesis in Radiotherapy Physics Program, ...
• Inhibition of Serum and Glucocortıcoıd Inducible Kinase 1 (Sgk1) in Triple Negative Breast Cancer 

  HAZNEDAROĞLU, Elif (Kanser Enstitüsü, 2018-07-18)

  Glucocorticoid receptor overexpression leads to poor prognosis in breast cancer, particularly in triple negative phenotype. This poor prognosis has been shown to be due to the activation of SGK1 (serum and glucocorticoid ...
• Meme Kanserinde, Normal Fibroblastlar ve Kanserle İlişkili Fibroblastların Monosit Çağrılması, Makrofaj Polarizasyonu ve İnvazyona Etkisi 

  GÖK YAVUZ, Betül (Kanser Enstitüsü, 2018)

  GÖK YAVUZ B., The Effect of Cancer Associated Fibroblasts and Normal Fibroblasts on Monocyte Recruitment, Macrophage Polarization and Invasion in Breast Cancer. Hacettepe University Institute of Health Sciences Ph.D Thesis ...
• Evaluation of Metadherin Expression in Breast Cancer 

  Ebrahimi, Mohammad Azim (Sağlık Bilimleri Enstitüsü, 2018)

  Metadherin gene (MTDH/ AEG-1/ Lyric) encodes a 582- aminoacid protein, metadherin (MTDH), which is almost undetectable by immunohistochemistry in normal breast tissue. MTDH expression is markedly increased in breast cancer ...
• Kanser Tanısı Alan Hastaların Birinci Derece Yakınlarında Sigara Bırakma Davranışının Değerlendirilmesi 

  HÜSEYİN, Beril (Kanser Enstitüsü, 2018)

  Tobacco use is one of the most important causes of morbidity and mortality. As a consequence, quitting smoking is a fundamental aim of primary prevention of diseases. Diagnosing a smoker or his/her relative with cancer may ...
• Effect of Calcıum Carbonate Encapsulatıon on the Oral Actıvıty of Cpg Olıgodeoxynucleotıdes and Assessment of the Response of Human Monocytes to Tlr Lıgands 

  KAYRAKLIOĞLU, Neslihan (Sağlık Bilimleri Enstitüsü, 2018-03)

  Toll-like receptor (TLR) ligands modulate immune responses and have been used in immunotherapy. Clinical trials designed to evaluate the utility of CpG ODN, a synthetic TLR9 ligand, relied on parenteral routes of administration. ...
• Investigation of Lung Cancer Cell Culture Supernatants Activated with Tlr Agonists Effect on Macrophage Polarization 

  Ahmadzadeh, Behnam (Kanser Enstitüsü, 2018)

  It is well known that inflammation is involved in the development of lung cancer. Macrophages in the tumor microenvironment are the anti-inflammatory M2 type and anti-tumor type M1. Inflammatory cytokines, such as IL-1β, ...
• Vajinal Kaf Brakiterapi Uygulamaları için Yoğunluk Ayarlı Aplikatör Tasarımı: Dozimetrik Fizibilite Çalışması 

  Biltekin, Fatih (Kanser Enstitüsü, )

  Depending on technological advances in radiotherapy, the use of three-dimensional (3D) treatment planning in brachytherapy (BRT) applications has provided a great advantage in terms of efficacy of treatment in gynecological ...
• Mikozis Fungoides Mikroçevresinde Bulunan Dermal Fibroblastların Anti-Tümör İmmün Yanıta Etkisi 

  Beksaç, Burcu (Sağlık Bilimleri Enstitüsü, 2017-12)

  Mycosis fungoides (MF) is the most common primary cutaneous T-cell lymphoma. The interaction of the neoplastic lymphocytes with their microenvironment is of crucial importance in disease progression. Cancer associated ...
• 3 Boyutlu Baskı Teknolojisi Kullanılarak Hastaya Özgün Konturlarla Oluşturulan Fantom Tasarımı ve Üretimi ile Mikro-Çok Yapraklı Kolimatör Tabanlı Beyin ve Başboyun Yoğunluk Ayarlı Radyoterapi Planlarının Kalite Kontrolü 

  SUNEL, Sercan (Sağlık Bilimleri Enstitüsü, 2017)

  SUNEL, S. Quality control of micro-multileaf collimator based brain and head-and-neck intensity modulated radiotherapy plans with patient-specific phantom design and production using 3D printing technology. Hacettepe ...
• 3′End Maturation of Human Telomerase Rna Component (Terc) and Its Effects on Telomere Dynamics 

  BOYRAZ, BARIŞ (Sağlık Bilimleri Enstitüsü, 2017-09-15)

  Telomerase RNA Component (TERC) is the non-coding RNA template and scaffold of the telomerase holoenzyme. TERC level has been shown to be a limiting factor for telomerase activity, lower levels resulting in telomere diseases ...
• Modulation of Glucocorticoid Induced Tumor Necrosis Factor Receptor (GITR)-GITR Ligand (GITRL) Interaction in Breast Cancer Cells Under the Control of Ataxia Telangiectasia Mutated (ATM) Promoter 

  Uluata Dayanç, Bengisu (Kanser Enstitüsü, 2017-07-21)

  Treatment response for basal-like breast cancers (BLBC) is limited and this aggressive breast cancer sub-type has poor prognosis and high mortality. Our first aim is to investigate ATM activity in BLBC cell lines with ...
• The Effect of Acute Myeloid Leukemia Cells Expressing PD-L2 Co-Stimulatory Molecule on Helper T Cell Activation 

  Tavukçuoğlu, Ece (Sağlık Bilimleri Enstitüsü, 2017-07-25)

  The binding of PD-1 to its ligands (PD-L1 and PD-L2) inhibits and/or regulates T cell responses. Myeloid leukemia cells can express both co-activatory and co-inhibitory molecules simultaneously. The function of PD-L1 in ...
• Kronik Periodontiti Olan Hastalarda Kanser İnsidansının Değerlendirilmesi 

  ÖMER, DİZDAR (Kanser Enstitüsü, 2017)

  Previous studies have noted possible associations between periodontitis and the risk of various cancers, particularly head and neck cancers, esophageal cancer, lung cancer, pancreatic cancer, breast cancer and non-Hodgkin ...
• Gastrointestinal Sistem Kanserli Hastalarda Mide Doluluğunun Radyoterapiye Etkisi 

  Tuğlu, Özveri (Kanser Enstitüsü, 2017)

  In the treatment of gastrointestinal system (GIS) cancers, radiotherapy (RT) is frequently applied as three dimensional conformal RT (3BKRT) or intensity adjusted RT (YART). GIS tumors are very sensitive to environmental ...
• Cyberknife® X-Sight® Vertebra Takip Sisteminin Vertebra Dışı Lezyonlarda Uygulanabilirliğinin Araştırılması 

  Eken, Selami (Kanser Enstitüsü, 2017-03-25)

  One of devices which uses the ablative dose for the Stereotactik body radiation theraphy (SBRT) is CyberKnife® Stereotactic Radiosurgery System. This device, has different tracking system from other devices. This systems ...
• Vulva Kanserinde Elektron-YART Hibrit Tedavi Modalitesinin Tedavi Planlama Sistemi ve Dozimetrik Yöntemlerle İncelenmesi 

  Akmanlar, Melisa (Sağlık Bilimleri Enstitüsü, 2017-02-20)

  In recent years, in the treatment of vulvar cancer, intensity modulated radiation therapy (IMRT) have been used instead of 3 dimensional conformal radiotherapy (3DCRT). In this thesis study, 7 patients who were diagnosed ...
• Cyberknife Synchrony® Solunum Takip Sisteminin Polimer Jel Dozimetre ile Üç Boyutlu Performans Analizi 

  Şahin, Meryem Cansu (Kanser Enstitüsü, 2017-02-20)

  ŞAHİN, M. C. Three Dimensional Performance Analysis Of Cyberknife Synchrony® Respiratory Tracking System Using Polymer Gel Dosimeter. Hacettepe University Institute of Health Sciences, Thesis in Radiotherapy Physics ...

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