BOR NİTRÜR KAPLANMIŞ İMPLANTLARIN ANTİBAKTERİYEL ETKİNLİĞİNİN İNCELENMESİ
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Implant-related infections aren’t a rare medical condition in orthopedics and traumatology practice. Infection resistant implants are used in the prevention and treatment of implant-related infections and new implant surfaces are being launched every day and new ones are being developed. In this study, four groups of titanium alloy implants with different coating parameters were covered with boron nitride and compared with the control group. For each group and control group, microbiological efficacy was investigated using disc diffusion and colony counting method. In addition, electron microscopy was used to examine the effect of boron nitride on prevention of biofilm production. Experiments for colony count and electron microscopy were performed with three different species of biofilm-forming bacteria. According to disc diffusion method and colony count, implants coated with boron nitride showed no difference in antibacterial activity compared with control group. While electron microscopy examination revealed bacterial clusters and biofilm formation on the control group implants, there was no biofilm formation in boron nitride covered implant groups. As a result, although boron nitride covered implants did not have antimicrobial activity, they showed an inhibitory effect on formation of biofilm.