Raynaud Fenomeni Olan Kişilerde Allerjik Hastalıkların Sıklığı
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The Raynaud phenomenon (RP) is an exaggerated vascular response to cold or emotional stress. Cold is also a trigger factor for allergic diseases like asthma, vasomotor rhinitis and urticaria (cold urticaria, idiopathic urticaria, dermographism). The aim of the present study was to investigate the prevalance of allergic diseases in patients with primary and secondary Raynaud's phenomenon. Consecutive 53 patients with Raynaud phenomenon who were followed in rheumotology department and volunteered for allergic evaluation, were evaluted between April 2013-September 2013. An additional 20 patients with rheumatic disease and without Raynaud phenomenon were included as control group. A questionnaire evaluating the presence of allergic diseases were applied to all patients. Depending on oral corticosteroid usage, either skin prick test or specific IgE(phadiatop) requested. Pulmonary function test and ice cube test were performed for all patients. Among the patients included in the study, 90.4%were women and 72.6%had RF. The most common rheumatic diseases were scleroderma and rheumatoid arthritis. Patients with vasomotor rhinitis (12.3%), dermographism (8.2%) and cold urticaria (4.1%) have had RF. Fifty three point four percent of all patients had at least one allergic disease. Having allergic diseases was associated with primary RF (OR 9.24, 95%CI 1.05-81.05). In conclusion, Raynaud's phenomenon has been shown to be associated with cold related allergic disaeses such as asthma, vasomotor rhinitis, cold urticaria and dermographism. In addition, the frequency of allergic diseases in patients with rheumatoid arthritis was not less than the normal population.