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An Automated Image Analysis System Can be Beneficial in Preclassification of Leucocytes in Children with Hematological Disease.
(WILEY, 2011)This study was aimed to evaluate the analytical performance of an automated image analysis system (a pilot model of Diff Master™ Octavia) for the preclassification of leucocytes in children with hematological disease. ... -
MÜFREDAT-I TIBBİYE (1290/HİCRİ) ADLI YAZMA ESERDE GEÇEN BAZI BİTKİLERİN TIP TARİHİ AÇISINDAN DEĞERLENDİRİLMESİ
(Sağlık Bilimleri Enstitüsü, 2020)The work titled “Müfredat-ı Tıbbiye” consists of lecturers written by Veterinarian İsmail Hilmi Bey. The only known copy is in the Koyunoğlu Museum. The date of writing is specified as 1290 Arabi by İsmail Hilmi Bey's ... -
Çocuk Yanık Yoğun Bakım Ünitesi Yatak Başı Klinik Ekip Vizitlerinde Çocuk Cerrahi Asistanlarının Vizit Yönetim Becerilerinin Değerlendirilmesi ve Klinik Vizit Sürecinin İncelenmesi.
(Sağlık Bilimleri Enstitüsü, 2020-09)The research was carried out in a mixed design in order to examine the process of (clinical) pediatric surgical physician visits performed in the Pediatric Burn Intensive Care Unit and to evaluate the bedside round management ... -
AEBP1/ACLP'nin Protein Etklileşim Ağının Proteomik ve Biyoinformatik Yöntemlerle Araştırılması
(Sağlık Bilimleri Enstitüsü, 2020)Extracellular Matrix (ECM) is the mechanical supportive structure for cells and tissues. Chronic damage may cause loss of ECM integrity that may result in fibrosis which is the progressive and irreversible accumulation of ... -
Spinal Müsküler Atrofi Hastalarının Fibroblast Kültürlerinde Mikrotübül Stabilitesinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2020)Spinal muscular atrophy (SMA), which is characterized by motor neuron loss and muscle atrophy, is a neurodegenerative disease primarily in childhood. In SMA, Survival of motor neuron 1 (SMN1) gene mutations lead to the ... -
Mikrodizi Gen İfade Verilerinde Farklı Öznitelik Seçim Yöntemleri ile Sınıflama Yöntemlerinin Performanslarının Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2020-08-07)Bioinformatics is an interdisciplinary branch of science that combines statistics, biology, computing, mathematics, and genetics, and thanks to the analysis in bioinformatics, it can be shown which abnormalities causes ... -
Determination of Lipid Metabolism Alterations and Their Association with Disease Pathogenesis in Sickle Cell Disease
(Sağlık Bilimleri Enstitüsü, 2020-07-07)Sickle cell disease (SCD) is a hemoglobinopathy that causes severe anemia and is characterized by lipid abnormalities, oxidative stress and chronic inflammation. It is caused by a single point-mutation in the beta globin ... -
Bisfenol A’nın Hepg2 Hücrelerine Olan Etkilerinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2020)Öz, E. Examination of the Effects of Bisphenol A on HepG2 Cells. Hacettepe University Graduate School of Health Sciences, Biochemistry Program, Master Thesis, Ankara, 2020. In this study, it was aimed to determine the ... -
Biyotıpta Gelişen Teknolojilerdeki Etik ve İnsan Hakları Sorunları
(Sağlık Bilimleri Enstitüsü, 2020)Close interaction between life and engineering sciences, emerging nanotechnologies, biotechnologies, information communication technologies, and the use of neurotechnology in medicine have led to the development of new ... -
Improvement of Germ Stem Cell Pool by Leptin Supplementation and Gene Editing for Male Infertility
(Sağlık Bilimleri Enstitüsü, 2020-06-12)Infertility affects up to 12-15% of sexually active couples, and male factors contribute about 30-55% of these cases. Infertility can be caused by injuries, genetic factors, exposure to toxicants, immune-suppressive and ... -
TROMBOSİTOPENİK HASTALARDA PLATELET YÜZEY ANTİJENLERİNİN AKIM SİTOMETRİ İLE İNCELENMESİ VE KANAMA DİYATEZİ İLE İLİŞKİSİNİN ARAŞTIRILMASI
(Tıp Fakültesi, 2019)Bleeding is mainly associated with low platelet counts and platelet dysfunctions. Although there are several methods to evaluate platelet function, they require large amount of blood and platelet counts more than 150.000/µl. ... -
Çocukluk Çağı Arterial İskemik İnmeleri Ve Sinövenöz Trombozlarında İlişkili Faktörler, Etiyolojinin Belirlenmesi ve Nörolojik Sonuçlar
(Tıp Fakültesi, 2017-09)Pediatric stroke is rare compared to adults, however causes long term morbidity and mortality. We retrospectively analysed children beyond newborn period, diagnosed with acute stroke and followed up at Hacettepe University ... -
Mycobacterium Tuberculosis Klinik İzolatlarında Yeni Antitüberküloz İlaçlar Olan Bedaquiline ve Delamanid'in MİK Değerlerinin ve Dirence Neden Olan Mutasyonların Saptanması
(Sağlık Bilimleri Enstitüsü, 2020)The purpose of this study is to detect the minimum inhibitory concentration (MIC) values of these novel drugs against to 101 resistant-M.tuberculosis clinical isolates with MGIT 960 automatized liquid culture system ... -
Fenilketonüride Öğrenme Bellek Mekanizmasının Dişi Ve Erkek Sıçanlarda cAMP/PKA/CREB/BDNF Yolağı Üzerinden İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2020)Phenylketonuria is a rare hereditary metabolic disease characterized by deficiency of phenylalanine hydroxylase. The absence of enzyme causes blood phenylalanine levels to rise. If patients are not treated, irreversible ... -
Twelve Years Of Fluconazole In Clinical Practice: Global-Trends In Species Distribution And Fluconazole Susceptibility Of Bloodstream Isolates Of Candida
(ESCMID, 2004)We determined the species distribution and in-vitro susceptibility of 6082 bloodstream infection (BSI)isolates ofCandidaspp. collected from 250 medical centres in 32 nations over a 10-year period from 1992through 2001. The ... -
The Role Of Reactive Oxygen Species And Oxidative Stress In Carbon Monoxide Toxicity: An In-Depth Analysis
(Maney Publishing, 2014)The underlying mechanism of the central nervous system (CNS) injury after acute carbon monoxide (CO) poisoning is interlaced with multiple factors including apoptosis, abnormal inflammatory responses, hypoxia, and ... -
Meta Analizinde Aykırı Değerlerin İncelenmesi Ve Aykırı Değerlerin Olduğu Durumda Kullanılan Yöntemlerin Karşılaştırılması
(Sağlık Bilimleri Enstitüsü, 2020)In this thesis, it is aimed to determine outliers in meta-analysis, and if there is an outlier, it is aimed to find out which method is more efficient in predicting effect size and variance among studies and better to ... -
Kistik Fibrozis Hastalarında Fenotipik Ciddiyeti Etkileyen Genlerin ve İlişkili Yolakların Araştırılması
(Sağlık Bilimleri Enstitüsü, 2020-03-02)Cystic fibrosis, the most common autosomal recessive disease, is caused by mutations in the Cystic Fibrosis Transmembrane Regulator (CFTR) gene. In addition to CFTR mutations, modifier genes and environmental factors play ... -
Kolestaz Hastalarında Safra Asitlerinin Lc-Ms/Ms ile Araştırılması ve Olası Biyobelirteçlerin Belirlenmesi
(Sağlık Bilimleri Enstitüsü, 2020-02-18)Inborn errors of bile acid synthesis (IEBAS) are autosomal recessively inherited disorders that are resulted from the deficiencies in the structure or function of the enzymes involved in the synthesis of bile acids, causing ... -
Rapid Determination of Rifampin Resistance in Clinical Isolates of Mycobacterium Tuberculosis by Real-Time Pcr
(Amer Soc Microbiology, 2005)Real-time PCR was used to determine rifampin resistance in clinical isolates of Mycobacterium tuberculosis. Ninety-six rifampin-resistant isolates and 23 rifampin-susceptible isolates were included in the study. A 305-bp ...
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