• Alx4 Dysfunction Disrupts Craniofacial and Epidermal Development 

      Kayserili, Hülya; Uz, Elif; Niessen, Carien; Vargel, İbrahim; Alanay, Yasemin; Tuncbilek, Gökhan; Yigit, Gokhan; Uyguner, Oya; Candan, Sukru; Okur, Hamza; Kaygin, Serkan; Balci, Sevim; Mavili, Emin; Alikasifoglu, Mehmet; Haase, Ingo; Wollnik, Bernd; Akarsu, Nurten Ayse (Oxford Univ Press, 2009)
      Genetic control of craniofacial morphogenesis requires a complex interaction of numerous genes encoding factors essential for patterning and differentiation. We present two Turkish families with a new autosomal recessive ...
    • Assessment Of Survival Rates Compared According To The Tamai And Yamano Classifications In Fingertip Replantations 

      Dadaci, Mehmet; Ince, Bilsev; Altuntas, Zeynep; Bitik, Ozan; Kamburoglu, Haldun Onuralp; Uzun, Hakan (2016)
      Background: The fingertip is the most frequently injured and amputated segment of the hand. There are controversies about defining clear indications for microsurgical replantation. Many classification systems have been ...
    • Auricular Cartilage Repair Using Cryogel Scaffolds Loaded With Bmp-7-Expressing Primary Chondrocytes 

      Odabas, S.; Feichtinger, G. A.; Korkusuz, P.; Inci, I.; Bilgic, E.; Yar, A. S.; Cavusoglu, T.; Menevse, S.; Vargel, I.; Piskin, E. (Wiley, 2013)
      The loss of cartilage tissue due to trauma, tumour surgery or congenital defects, such as microtia and anotia, is one of the major concerns in head and neck surgery. Recently tissue-engineering approaches, including gene ...
    • Congenital Breast Malformations 

      Lucas, Armand; Nasir, Serdar (Springer-Verlag London Ltd, 2010)
      Congenital breast deformities pose a challenging dilemma in plastic surgery. The expression of the abnormality maybe complete, and anatomic components are often missing, deformed, or weakened. Most breasts are naturally ...
    • De Novo Mutations In Smchd1 Cause Bosma Arhinia Microphthalmia Syndrome And Abrogate Nasal Development 

      Gordon, Christopher T.; Xue, Shifeng; Yigit, Goekhan; Filali, Hicham; Chen, Kelan; Rosins, Nadine; Yoshiura, Koh-ichiro; Oufadem, Myriam; Beck, Tamara J.; McGowan, Ruth; Magee, Alex C.; Altmueller, Janine; Dion, Camille; Thiele, Holger; Gurzau, Alexandra D.; Nuernberg, Peter; Meschede, Dieter; Muehlbauer, Wolfgang; Okamoto, Nobuhiko; Varghese, Vinod; Irving, Rachel; Sigaudy, Sabine; Williams, Denise; Ahmed, S. Faisal; Bonnard, Carine; Kong, Mung Kei; Ratbi, Ilham; Fejjal, Nawfal; Fikri, Meriem; Elalaoui, Siham Chafai; Reigstad, Hallvard; Bole-Feysot, Christine; Nitschke, Patrick; Ragge, Nicola; Levy, Nicolas; Tuncbilek, Goekhan; Teo, Audrey S. M.; Cunningham, Michael L.; Sefiani, Abdelaziz; Kayserili, Huelya; Murphy, James M.; Chatdokmaiprai, Chalermpong; Hillmer, Axel M.; Wattanasirichaigoon, Duangrurdee; Lyonnet, Stanislas; Magdinier, Frederique; Javed, Asif; Blewitt, Marnie E.; Amiel, Jeanne; Wollnik, Bernd; Reversade, Bruno (Nature Publishing Group, 2017)
      Bosma arhinia microphthalmia syndrome (BAMS) is an extremely rare and striking condition characterized by complete absence of the nose with or without ocular defects. We report here that missense mutations in the epigenetic ...
    • Differential Expression Patterns Of Metastasis Suppressor Proteins In Basal Cell Carcinoma 

      Bozdoğan, Önder; Yulug, Isık G.; Vargel, İbrahim; Çavuşoğlu, Tarık; Karabulut, Ayşe A.; Karahan, Gurbet; Sayar, Nilufer (Wiley, 2015)
      BackgroundBasal cell carcinomas (BCCs) are common malignant skin tumors. Despite having a significant invasion capacity, they metastasize only rarely. Our aim in this study was to detect the expression patterns of the ...
    • Embolization Of High-Flow Craniofacial Vascular Malformations With Onyx 

      Arat, A.; Cil, B. E.; Vargel, I.; Turkbey, B.; Canyigit, M.; Peynircioglu, B.; Arat, Y. O. (Amer Soc Neuroradiology, 2007)
      BACKGROUND AND PURPOSE: Various techniques and materials have been used for the endovascular treatment of craniofacial high-flow arteriovenous vascular malformations, because their rarity precludes standardization of their ...
    • Evaluation Of The Effectiveness Of Biodegradable Electrospun Caprolactone And Poly(Lactic Acid-E-Caprolactone) Nerve Conduits For Peripheral Nerve Regenerations In A Rat Sciatic Nerve Defect Model 

      Dadaci, Mehmet; Karagulle, Nimet; Sonmez, Erhan; Dadaci, Zeynep; Isci, Evren Tevfik; Ince, Bilsev; Vargel, Ibrahim; Piskin, Erhan; Erk, Ali Yucel (Tubitak Scientific & Technical Research Council Turkey, 2016)
      Background/aim: The aim of this study was to compare electrospun caprolactone (EC) and poly(lactic acid-epsilon-caprolactone) (PLCL) nerve conduits with nerve graft in a rat sciatic nerve defect model. Materials and methods: ...
    • Ewing'S Sarcoma Of The Mandible Misdiagnosed As Periodontal Inflammation: Report Of Three Cases 

      Balkaya, Eda; Bozkurt, Ceyhun; Aksu, Ali Emre; Ozmen, Selahattin; Incesoy-Ozdemir, Sonay; Sahin, Gurses (Turkish J Pediatrics, 2017)
      Ewing's sarcoma (ES) is the second most common childhood primary malignant tumor of the bone. The most popular locations of ES are long bones and pelvis. The involvement of the mandible is very rare in childhood. In last ...
    • Experimental Composite Tissue Transplantation Models 

      Siemionow, Maria; Nasir, Serdar (Springer-Verlag London Ltd, 2010)
      Advanced microsurgical techniques have allowed performing different composite tissue allotransplantations (CTA), although immunology and pharmacotherapy still have many unresolved questions. Different CTA models were ...
    • Focused Rf Hyperthermia Using Magnetic Fluids 

      Tasci, T. Onur; Vargel, Ibrahim; Arat, Anil; Guzel, Elif; Korkusuz, Petek; Atalar, Ergin (Wiley, 2009)
      Heat therapies such as hyperthermia and thermoablation are very promising approaches in the treatment of cancer. Compared with available hyperthermia modalities, magnetic fluid hyperthermia (MFH) yields better results in ...
    • Functional Outcomes Of Mandibular Distraction For The Relief Of Severe Airway Obstruction And Feeding Difficulties In Neonates With Pierre Robin Sequence 

      Konas, Ersoy; Calis, Mert; Bitik, Ozan; Yigit, Sule; Korkmaz, Ayse; Yurdakok, Murat; Tuncbilek, Gokhan (Turkish J Pediatrics, 2016)
      The purpose of this study was to review the application of mandibular distraction to relieve severe airway obstruction or feeding problems of neonates. Thirteen neonates with Pierre Robin sequence who underwent bilateral ...
    • Groin And Thigh Reconstructions With Pedicled Rectus Abdominis Myocutaneous Flaps 

      Uzun, Hakan; Bitik, Ozan; Baltu, Yahya; Dadaci, Mehmet; Kayikcioglu, Aycan Ugur (Tubitak Scientific & Technical Research Council Turkey, 2017)
      Background/aim: Resection of tumors from the groin and thigh regions with safe margins often results in significant soft tissue defects, which preclude primary closure. This study presents a series of rectus abdominis ...
    • Meta-Analysis Of 13 Genome Scans Reveals Multiple Cleft Lip/Palate Genes With Novel Loci On 9Q21 And 2Q32-35 

      Marazita, ML; Murray, JC; Lidral, AC; Arcos-Burgos, M; Cooper, ME; Goldstein, T; Maher, BS; Daack-Hirsch, S; Schultz, R; Mansilla, MA; Field, LL; Liu, Y; Prescott, N; Malcolm, S; Winter, R; Ray, A; Moreno, L; Valencia, C; Neiswanger, K; Wyszynski, DF; Bailey-Wilson, JE; Albacha-Hejazi, H; Beaty, TH; McIntosh, I; Hetmanski, JB; Tuncbilek, G; Edwards, M; Harkin, L; Scott, R; Roddick, LG (Univ Chicago Press, 2004)
      Isolated or nonsyndromic cleft lip with or without cleft palate (CL/P) is a common birth defect with a complex etiology. A 10-cM genome scan of 388 extended multiplex families with CL/P from seven diverse populations (2,551 ...
    • Metastasis Suppressor Proteins In Cutaneous Squamous Cell Carcinoma 

      Bozdogan, Onder; Vargel, Ibrahim; Cavusoglu, Tarik; Karabulut, Ayse A.; Karahan, Gurbet; Sayar, Nilufer; Atasoy, Pinar; Yulug, Isik G. (Elsevier Gmbh, Urban & Fischer Verlag, 2016)
      Cutaneous squamous cell carcinomas (cSCCs) are common human carcinomas. Despite having metastasizing capacities, they usually show less aggressive progression compared to squamous cell carcinoma (SCC) of other organs. ...
    • Microfat Grafting In Nasal Surgery 

      Erol, O. Onur (Oxford Univ Press Inc, 2014)
      Background: Injectable fillers are sometimes necessary to correct slight skin irregularities. However, there have been reports of necrosis after injection of alloplastic materials and heterogeneous transplants. On the other ...
    • Microvascular Tissue Transfers In The Elderly: Safety Analysis For A Challenging Area 

      Aksu, Ali Emre; Ustun, Galip Gencay; Bitik, Ozan; Kara, Murat; Sakarya, Ahmet Hamdi; Safak, Tunc (Tubitak Scientific & Technical Research Council Turkey, 2017)
      Background/Aim: Due to increased average life expectancy, the number of elderly patients requiring complex reconstructive microsurgical procedures is rising. Age, comorbid conditions, and location of operation are all ...
    • Mutations In The Interleukin Receptor Il11Ra Cause Autosomal Recessive Crouzon-Like Craniosynostosis 

      Keupp, Katharina; Li, Yun; Vargel, Ibrahim; Hoischen, Alexander; Richardson, Rebecca; Neveling, Kornelia; Alanay, Yasemin; Uz, Elif; Elcioğlu, Nursel; Rachwalski, Martin; Kamaci, Soner; Tunçbilek, Gökhan; Akin, Burcu; Grötzinger, Joachim; Konas, Ersoy; Mavili, Emin; Müller-Newen, Gerhard; Collmann, Hartmut; Roscioli, Tony; Buckley, Michael F; Yigit, Gökhan; Gilissen, Christian; Kress, Wolfram; Veltman, Joris; Hammerschmidt, Matthias; Akarsu, Nurten A; Wollnik, Bernd (2013)
      We have characterized a novel autosomal recessive Crouzon-like craniosynostosis syndrome in a 12-affected member family from Antakya, Turkey, the presenting features of which include: multiple suture synostosis, midface ...